Neglected Tropcial Diseases

[Translate to english:] [alle Inhalte aus dem Jahresbericht BNI 2010/2011]

Apart from Dengue fever, leishmaniasis presumably is the most important of the „neglected diseases“. In the past years, WHO made particular efforts to negotiate with the pharmaceutical industry price reductions for the most needed drugs. Of concern is the increasing drug resistance of leishmania.

Sickle cell disease in Hamburg

Sickle cell disease is an inherited disorder prevalent only in populations from malaria endemic areas. Affected children may suffer from pneumonias and other life-threatening complications early in life.

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How mycobacteria leave cells after infection

Mycobacteria like Mycobacterium tuberculosis reside and multiply inside our cells. While their invasion and survival are under intense investigation, it is largely unknown how they leave the cells – something they need to do to spread the infection.

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Chaperone safeguards Leishmania's survival

Although it is usually very hot in their homelands, parasites that are transmitted by insects must survive a heat shock when they encounter humans or other warm-blooded organisms. With temperatures exceeding 40°C, our bodies are much hotter than the insects’ or the tropics.

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Into the eye

In a survey in Central Africa, o