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Prof. Dr. Jürgen MayAbteilung InfektionsepidemiologiePhone: +49 40 42818-369
Mail: may(at)bnitm.de

Dr. Eleonora SchönherrPresse- & ÖffentlichkeitsarbeitPhone: +49 40 42818-269
Mail: presse(at)bnitm.de

Julia HäberleinPresse- & ÖffentlichkeitsarbeitPhone: +49 40 42818-264
Mail: presse(at)bnitm.de

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New ANTICOV study platform for African doctors

Largest clinical trial for treatment of COVID-19 cases in Africa begins

Hamburg/Kumasi. Thirteen African countries and an international network of research institutions have jointly established a study platform to be able to conduct clinical trials for early treatment of COVID-19 disease. The Kumasi Centre for Collaborative Research (KCCR) in Ghana is also participating in the trial in cooperation with the Bernhard Nocht Institute for Tropical Medicine (BNITM).

“ANTICOV” is a large-scale trial designed to identify therapeutics that are able to prevent progression of COVID-19 to severe disease. An initial study is expected to enroll 2,000 to 3,000 COVID-19 patients from Burkina Faso, Cameroon, Côte d’Ivoir, the Democratic Republic of Congo (DRC), Equatorial Guinea, Ethiopia, Ghana, Guinea, Kenya, Mali, Mozambique, Sudan and Uganda.

“The number of COVID-19 cases and deaths in many African countries have turned out to be lower than initially predicted. But we need to prepare for a surge in cases and respond with potential therapeutic options that are suitable for African patients. We are therefore pleased to be among the institutions participating in this study,” said Dr. John Amuasi, Head of the Global Health and Infectious Disease Research Group at KCCR. The aim of the study is to treat patients with COVID-19 in the early stages of the disease to prevent hospitals from being overwhelmed, given the limited intensive care facilities in Africa.

Prof. Jürgen May, Head of the Department of Infectious Disease Epidemiology at BNITM, welcomes the launch of the study platform for African physicians. In cooperation with the German Centre for Infection Research (DZIF), the BNITM has taken over the responsible leadership of the study in Ghana. “There are only few clinical trials investigating treatments that can be administered early in the course of infection to prevent disease progression in African patients with COVID-19,” said May. The ANTICOV consortium is funded by the German Federal Ministry of Education and Research (BMBF) and the global health initiative “Unitaid”.

 


Press material (Englisch)

https://www.dropbox.com/sh/vdt9hypc8b4nopz/AAAhTL9sYJPdUYssNQv8jLwva?dl=0

  • Official ANTICOV press release of the DND initiative
  • ANTICOV Backgrounder
  • ANTICOV FAQs
  • Statements from ANTICOV consortium members, partners, and donors

Background information

The ANTIVCOV research project was developed with support from the African Vaccine Regulatory Forum (AVAREF). The AVAREF is a platform set up by the World Health Organisation in 2006, composed of representatives of African ethics committees and regulatory authorities, to simplify and accelerate the review of clinical trials for COVID-19 at country level.
The ANTICOV consortium has mobilised a broad network of different partners with extensive experience in clinical research, belonging to the "COVID-19 Coalition for Clinical Research", which was launched in April 2020:

  • Alliance for International Medical Action (ALIMA), France / Senega
  • Agence Nationale de Recherche sur le Sida et les Hépatites Virales (ANRS), France
  • Bahir Dar University, Ethiopia
  • Barcelona Institute for Global Health (ISGlobal), Spain
  • Bernhard-Nocht-Institut für Tropenmedizin (BNITM), Germany
  • Centre Muraz, Institut National de Santé Publique, Burkina Faso
  • Centre for Research in Therapeutic Sciences, Kenya
  • Centro de Investigação em Saúde de Manhiça, Mozambique
  • Centro de Investigação e Treino em Saúde da Polana Caniço (CISPOC), Instituto Nacional de Saúde, Mozambique
  • Centre Pasteur du Cameroun (CPC), Cameroon
  • Centre Pour Le Développement Des Vaccins, Ministry of Health, Mali
  • Centre Suisse de Recherches Scientifiques (CSRS), Côte d’Ivoire
  • Drugs for Neglected Diseases initiative (DNDi), Switzerland - (coordinating partner)
  • Epicentre, France
  • Foundation for Innovative New Diagnostics (FIND), Switzerland
  • Ifakara Health Institute, Tanzania
  • Infectious Diseases Data Observatory (IDDO), United Kingdom
  • Institute of Endemic Diseases, University of Khartoum, Sudan
  • Institute of Tropical Medicine, Antwerp (ITM), Belgium
  • Institut National de Recherche Biomédicale (INRB), Democratic Republic of Congo
  • The Kenya Medical Research Institute (KEMRI), Kenya
  • Kumasi Centre for Collaborative Research in Tropical Medicine (KCCR), Ghana
  • Medicines for Malaria Venture (MMV), Switzerland
  • Swiss Tropical and Public Health Institute (Swiss TPH), Switzerland
  • Université de Bordeaux - Institut National de la Santé et de la Recherche Médicale (INSERM), France
  • University of Gondar, Ethiopia

Press contacts

BNITM:

Prof. Jürgen May, Head of Department Infection Epidemiology, may(at)bnitm.de, Tel. 040 42818-369
Dr. Eleonora Schönherr, Press Office, presse(at)bnitm.de, Tel. 040 42818-269

KCCR:

Dr. John Amuasi, Head of Global Health and Infectious Diseases, amuasi(at)kccr.de , Tel. +233 3220 60351 Ext 230

DNDi:

Frédéric Ojardias (Geneva), fojardias(at)dndi.org, +41 79 431 62 16
Linet Otieno (Nairobi), latieno(at)dndi.org, +254 733 624 206
Ilan Moss (New York), imoss(at)dndi.org, +1 646 266 5216
Francine Ngalula (Kinshasa), francinengal(at)gmail.com, +243 816 402 389


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