Neglected Tropcial Diseases

[Translate to english:] [alle Inhalte aus dem Jahresbericht BNI 2010/2011]

Apart from Dengue fever, leishmaniasis presumably is the most important of the „neglected diseases“. In the past years, WHO made particular efforts to negotiate with the pharmaceutical industry price reductions for the most needed drugs. Of concern is the increasing drug resistance of leishmania.

Sickle cell disease in Hamburg

Sickle cell disease is an inherited disorder prevalent only in populations from malaria endemic areas. Affected children may suffer from pneumonias and other life-threatening complications early in life.

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How mycobacteria leave cells after infection

Mycobacteria like Mycobacterium tuberculosis reside and multiply inside our cells. While their invasion and survival are under intense investigation, it is largely unknown how they leave the cells – something they need to do to spread the infection.

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Chaperone safeguards Leishmania's survival

Although it is usually very hot in their homelands, parasites that are transmitted by insects must survive a heat shock when they encounter humans or other warm-blooded organisms. With temperatures exceeding 40°C, our bodies are much hotter than the insects’ or the tropics.

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Into the eye

In a survey in Central Africa, ophthalmologists found a series of eye infections by parasites. After surgical removal of suspicious material, DNA tests identified parasites of the genus Armillifer, also called pentastomes.

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Animal model for scrub typhus

Scrub typhus is prevalent in large areas of Asia and Oceania. It is caused by particularly small bacteria (Orientia tsutsugamushi), which are transmitted by the bites of mites.

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Effective short-term treatment of actinomycosis

A 30-year-old farmer from Savannakhet Province in Laos had developed on his right foot a large, brownish-coloured, painless swelling from which oozed a discharge containing bacteria of the Nocardia aobensis species.

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Confusing bacteremias and severe malaria

In sub-Saharan Africa, it is common practice to treat all children with fever for malaria. If they don’t get better within a few days, other causes for the disease are considered.

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Contact

Dr. Jessica Tiedke

Laura Zimmermann

Public Relations

Tel.: +49 40 42818-264

Fax: +49 40 42818-265

E-Mail:
presse@bnitm.de

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