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Apart from Dengue fever, leishmaniasis presumably is the most important of the „neglected diseases“. In the past years, WHO made particular efforts to negotiate with the pharmaceutical industry price reductions for the most needed drugs. Of concern is the increasing drug resistance of leishmania.
For many decades, compounds containing antimony have been the most important drugs to treat leishmaniasis. Antimony is related to arsenic.
As in almost all infectious diseases drug resistances cause increasing problems in the treatment of leishmaniases.