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The Ross River virus, endemic in Australia and the Pacific region, is transmitted by mosquitoes. It causes flu-like symptoms, but often also joint inflammation, which may persist over surprisingly long periods and may repeatedly recur over years.
In the blood of such patients, we found certain inflammatory proteins (so called cytokines) even prolonged times after the acute infection. They are signs of an uncured and persistent inflammatory reaction, which may even cause a loss of bone substance and subsequent fractures.
Dennis Tappe, Stephan Günther, Jonas Schmidt-Chanasit and external co-operation partners (see publication)