Overview

Lassa Fever in Guinea and Sierra Leone: rodent control, and seasonality of human exposure to rodents (LAROCS)

The LAROCS consortium involves 4 partners; BNI, Charité in Berlin, the university of Conakry in Guinea, and the university of Sierra Leone. It is multidisciplinary gathering epidemiology, anthropology, ecology and virology. In Guinea, the project will tempt to reduce the abundance of the Mastomys rodents in the view to decrease the occurrence of Lassa fever in humans. We will explore whether rodent trapping could be complemented by other means of rodent control like environmental hygiene. In Sierra Leone, the project will investigate whether the seasonal variation in Mastomys population occurs in rural villages.

All Publications

Department of Virology

No measurable adverse effects of Lassa, Morogoro and Gairo arenaviruses on their rodent reservoir host in natural conditions.
Mariën J, Borremans B, Gryseels S, Soropogui B, De Bruyn L, Bongo GN, Becker-Ziaja B, de Bellocq JG, Günther S, Magassouba N, Leirs H, Fichet-Calvet E
Parasit Vectors. 2017 Apr 27;10(1):210. doi: 10.1186/s13071-017-2146-0.

Rat-atouille: a mixed method study to characterize rodent hunting and consumption in the context of Lassa fever.
Bonwitt, J., Kelly, A., Ansumana, R., Sahr, F., Mari Saez, A., Borchert, M., Kock, R., Fichet-Calvet, E.
Ecohealth. 2016 Feb 19.

Evolutionary origins of hepatitis A virus in small mammals.
Drexler JF, Corman VM, Lukashev AN, van den Brand JM, Gmyl AP, Brünink S, Rasche A, Seggewiβ N, Feng H, Leijten LM, Vallo P, Kuiken T, Dotzauer A, Ulrich RG, Lemon SM, Drosten C; Hepatovirus Ecology Consortium.
Proc Natl Acad Sci U S A. 2015 Dec 8;112(49):15190-5. doi: 10.1073/pnas.1516992112.

Extending the "social": anthropological contributions to the study of viral haemorrhagic fevers.
Brown H, Kelly AH, Mari Saez A, Fichet-Calvet E, Ansumana R, Bonwitt J, Magassouba N, Sahr F, Borchert M.
PLoS Negl Trop Dis. 2015 Apr 16;9(4):e0003651. doi: 10.1371/journal.pntd.0003651. eCollection 2015 Apr.

Using modelling to disentangle the relative contributions of zoonotic and anthroponotic transmission: the case of lassa fever.
Lo Iacono G, Cunningham AA, Fichet-Calvet E, Garry RF, Grant DS, Khan SH, Leach M, Moses LM, Schieffelin JS, Shaffer JG, Webb CT, Wood JL.
PLoS Negl Trop Dis. 2015 Jan 8;9(1):e3398. doi: 10.1371/journal.pntd.0003398.

Lassa serology in natural populations of rodents and horizontal transmission.
Fichet-Calvet E, Becker-Ziaja B, Koivogui L, Günther S.
Vector Borne Zoonotic Dis. 2014 Sep;14(9):665-74. doi: 10.1089/vbz.2013.1484.

Seroepidemiological study reveals regional co-occurrence of Lassa- and Hantavirus antibodies in Upper Guinea, West Africa.
Klempa B, Koulemou K, Auste B, Emmerich P, Thomé-Bolduan C, Günther S, Koivogui L, Krüger DH, Fichet-Calvet E.
Trop Med Int Health. 2013 Mar;18(3):366-71. doi: 10.1111/tmi.12045.

Funding

Contact

Dr. Elisabeth Fichet-Calvet

Phone: +49 40 42818-932
Fax: +49 40 42818-941
E-Mail: fichet-calvet@bnitm.de


Technical staff

Beate Becker-Ziaja (-934)