Our publications at a glance
2021
X-ray screening identifies active site and allosteric inhibitors of SARS-CoV-2 main protease
- Günther S†*, Reinke PYA†, Fernández-García Y, Lieske J, Lane TJ, Ginn HM, Koua FHM, Ehrt C, Ewert W, Oberthuer D, Yefanov O, Meier S, Lorenzen K, Krichel B, Kopicki JD, Gelisio L, Brehm W, Dunkel I, Seychell B, Gieseler H, Norton-Baker B, Escudero-Pérez B, Domaracky M, Saouane S, Tolstikova A, White TA, Hänle A, Groessler M, Fleckenstein H, Trost F, Galchenkova M, Gevorkov Y, Li C, Awel S, Peck A, Barthelmess M, Schlünzen F, Lourdu Xavier P, Werner N, Andaleeb H, Ullah N, Falke S, Srinivasan V, França BA, Schwinzer M, Brognaro H, Rogers C, Melo D, Zaitseva-Doyle JJ, Knoska J, Peña-Murillo GE, Mashhour AR, Hennicke V, Fischer P, Hakanpää J, Meyer J, Gribbon P, Ellinger B, Kuzikov M, Wolf M, Beccari AR, Bourenkov G, von Stetten D, Pompidor G, Bento I, Panneerselvam S, Karpics I, Schneider TR, Garcia-Alai MM, Niebling S, Günther C, Schmidt C, Schubert R, Han H, Boger J, Monteiro DCF, Zhang L, Sun X, Pletzer-Zelgert J, Wollenhaupt J, Feiler CG, Weiss MS, Schulz EC, Mehrabi P, Karničar K, Usenik A, Loboda J, Tidow H, Chari A, Hilgenfeld R, Uetrecht C, Cox R, Zaliani A, Beck T, Rarey M, Günther S, Turk D, Hinrichs W, Chapman HN, Pearson AR, Betzel C, Meents A* |Note: † equal contributing first authors, * equal contributing corresponding authors
- Science. 372(6542): 642-646. doi:10.1126/science.abf7945
2020
Diketo acids inhibit the cap-snatching endonuclease of several Bunyavirales
- Fernández-García Y†*, Ter Horst S†, Bassetto M, Brancale A, Neyts J, Rogolino D, Sechi M, Carcelli M, Günther S, Rocha-Pereira J* |Note: † equal contributing first authors, * equal contributing corresponding authors
- Antiviral Research. 183: 104947. doi:10.1016/j.antiviral.2020.104947
Enhanced efficacy of endonuclease inhibitor baloxavir acid against orthobunyaviruses when used in combination with ribavirin
- Ter Horst S†, Fernandez-Garcia Y†*, Bassetto M, Günther S, Brancale A, Neyts J, Rocha-Pereira J* |Note: † equal contributing first authors, * equal contributing corresponding authors
- Journal of Antimicrobial Chemotherapy. 75(11): 3189–3193. doi:10.1093/jac/dkaa337
2017
Expression and purification of the surface proteins from Andes virus
- Beltrán-Ortiz CE, Starck-Mendez MF, Fernández Y, Farnós O, González EE, Rivas CI, Camacho F, Zuñiga FA, Toledo JR, Sánchez O
- Protein Expression and Purification. 139: 63-70. doi:10.1016/j.pep.2015.09.013
2016
Atomic structure and biochemical characterization of an RNA endonuclease in the N terminus of Andes virus L protein
- Fernández-García Y, Reguera J, Busch C, Witte G, Sánchez-Ramos O, Betzel C, Cusack S, Günther S, Reindl S
- PLoS Pathogens. 12(6): e1005635. doi:10.1371/journal.ppat.1005635
