Clinical evaluation of AntimalarialS tri-therapy with AtovAquone Proguanil for malaria treatment in African children

ASAAP is a 48-month lasting clinical trial research to evaluate the efficacy, safety, tolerability and pharmacokinetics of a new antimalarial drug combination, with particular focus on its successful application in one of the largest and most vulnerable demographics of Africa – i.e. children 0-5 years old. The overall aim is to develop new antimalarial treatments by combining existing, efficacious medicines for treatment of malaria in African children by promoting African and European research collaboration and strengthening the capacity of African institutions to conduct clinical research.

The project is being led and coordinated by Dr. Oumou Maïga-Ascofaré of the BNITM in Hamburg, Germany and the KCCR in Kumasi, Ghana under the authority of the Kwame Nkrumah University of Science and Technology (KNUST), in collaboration with:


France Dr. Jerome Clain and Dr. Michel Cot at MERIT (Paris) and Dr. Anna Cohuet at MIVEGEC (Montpellier) from the Institut de Recherche pour le Développement (IRD)
Mali Prof. Abdoulaye Djimde from the Université des Sciences, des Techniques et des Technologies de Bamako (USTTB) in Bamako, Mali
Benin Prof. Achille Massougbodji from the Institut de Recherche Clinique du Bénin (IRCB) in Abomey-Calavi, Benin
Gabon Dr. Ghyslain Mombo-Ngoma from the Center de Recherches Médicales de Lambaréné (CERMEL) in Lambaréné, Gabon
Burkina Faso Dr. Serge Yerbanga from the Institut des Sciences et Techniques (INSTech) in Bobo-Dioulasso, Burkina Faso
Germany Prof. Jürgen May and Prof. Michael Ramharter from the Bernhard-Nocht-Institut für Tropenmedizin (BNITM) in Hamburg, Germany
Ghana Dr. John Amuasi from KCCR and the department of Global Health at the KNUST School of Public Health in Kumasi, Ghana


ASAAP is part of the European and Developing Countries Clinical Trials Partnership 2 (EDCTP2) program supported by the European Union (EU) and receives funding from the German Federal Ministry of Education and Research (BMBF) and the National Institut of Health and Medical Research in France (INSERM).

Further information can be found on the ASAAP-project website and the EDCTP webpage.

Funding Period 2019-2023
Funding Body EDCTP (Grant agreement: RIA2017MC-2022)

Department of Infectious Disease Epidemiology

Porträtfoto von Prof. Dr. Jürgen May, eines erfahrenen freundlich blickenden Forschers
Head of Dept Infectious Diseases Epidemiology

Prof. Dr. Jürgen May

Telefon: +49 40 285380-402


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