©Minka Breloer Overview One quarter of the world population is infected with parasitic worms that are called helminths. To avoid being eliminated these parasites actively dampen the immune response of [...] ns. We use the parasitic nematode Strongyloides ratti to investigate this in the mouse system. We are interested in (i) the mechanisms of protective anti-helminth immunity, (ii) the mechanisms of helm [...] actively penetrate the skin of their rodent host and migrate within 2 days via the tissue to the head. L3 are swallowed, moult via a 4 th larval stage to parasitic adults and embed into the mucosa of the small

immune signaling pathways, need to be fine-tuned during infection, and some of these are regulated by miRNAs. miRNAs are non-coding RNAs of ~20 nucleotides in length that occur in mammals, plants and viruses [...] human miRNA profiles in the different cells that are involved during the major events of severe P. falciparum infection and cerebral malaria. The experiments are designed to monitor the first steps and role [...] Endothelial cells (ECs) maintain about 60000 miles of blood vessels in human body. They are heterogenous group of cells that are responsive to signals from microenvironment. ECs line the blood and lymphatic vessels

Functional characterization of novel drug targets Plasmodium -specific proteins that are essential for blood stage survival are attractive targets for therapeutic intervention. Their inhibition will only harm [...] century. Owing to the rapid emergence and spread of drug resistance, innovative intervention strategies are urgently needed and strictly depend on our improved understanding of the complex biology underlying [...] molecular machinery of the parasite’s digestive vacuole as well as other parasite adaptations that are essential for blood stage survival. By combining Cas9-mediated genetic engineering with a variety of

of mistrust. We are interested explore how the lack of trust gives rise to alternatives modes of institutionalizing mistrust in everyday practices of care and survival. Finally, we are interested in novel [...] lity, or participation — repeatedly called upon in public health recommendations to build trust — are emblematic examples for the institutionalization of mistrust. Instead of fighting mistrust, they support [...] articulation of doubt and suspicion, which paradoxically begets voluntary trust. More specifically, we are interested in how mistrust is institutionalized in global health research and interventions; how we

Sheet (.pdf) ↗ Preparation: Resources for Teaching and Capacity Strengthening Ensure that students are able to access the EDDi Serious Game (Windows / Web Player) and that devices fulfill the game's system [...] printout of the EDDi Reporting Sheet . Headphones can be recommended to students, though game sounds are not essential for completing the assignment. Beware: The game contains text and visuals only and does [...] Requirements: The EDDi Serious Game is available for Windows (.exe, all files from the zip folder are required for the game to run! ) and via web browser (Unity WebGL Player). ​Please note that no macOS

for schistosomiasis and epidemiology -SCHISDIMA Diagnostic tools adapted for poor resources settings are often lacking, especially for diseases of poverty such as schistosomiasis. For this reason, schistosomiasis [...] Madagascar, where schistosomiasis is highly endemic and no data regarding the performances of the test are available. Partners: University of Fianarantsoa , University of Antananarivo , Centre d’Infectiologie

Anmeldung. Diploma Course in Tropical Medicine & Hygiene 2026 The course dates for the coming year are 30 March - 26 June 2026 . The diploma course is a full-time, on-site course at the Bernhard Nocht Institute [...] HEALTH IN RESOURCE-LIMITED SETTINGS (LAB-SPHERE) Well-functioning and sustainable laboratory services are at the basis of strong health systems and crucial for improving public health and research capacities [...] efficient management. Moreover, areas where laboratory systems overlap and/or complement health systems are being considered. The course uses interactive, simulation-based exercises, as well as practical sessions

diagnostics was established in 2008. Since then, more than 3,000 suspected samples are tested every year, of which about 20% are positive for Lassa virus. New laboratory wings were built in 2014 and 2018 and [...] and ISTH happen every year to carry out projects and reinforce capacities. The activities in Nigeria are supported by the German Federal Foreign Office, the German Research Foundation (DFG), the German Ministry [...] Virales de l’Hôpital Régional de N’Zérékoré” (HRNZE) located in N’Zérékoré. All three laboratories are part of GHPP and contribute to the surveillance system of the country and to field studies on viral

infections Contact: Nicole Gilberger , Johanna Brinkel Worldwide, approximately 216 million people are infected with malaria resulting in 445,000 deaths each year. 91% of which occur in Africa and affect [...] method to make sure the infection is cleared. The aim of this project is to identify biomarkers that are specific for malaria and bacterial bloodstream infections in order to develop a point-of-care test

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