Our Publications

• Neutralizing and interfering human antibodies define the structural and mechanistic basis for antigenic diversion

  • Patel PN, Dickey TH, Hopp CS, Diouf A, Tang WK, Long CA, Miura K, Crompton PD, Tolia NH
  • Nat Commun. 2022 Oct 6;13(1):5888. doi: 10.1038/s41467-022-33336-3
  • 2022-10-06

• Atypical B cells up-regulate costimulatory molecules during malaria and secrete antibodies with T follicular helper cell support

  • Hopp CS, Skinner J, Anzick SL, Tipton CM, Peterson ME, Li S, Doumbo S, Kayentao K, Ongoiba A, Martens C, Traore B, Crompton PD
  • Sci Immunol. 2022 May 13;7(71):eabn1250. doi: 10.1126/sciimmunol.abn1250
  • 2022-05-13

• Assessment of Plasmodium falciparum Antigen-Specific B Cells

  • Hopp CS, Taylor JJ, Crompton PD
  • Methods Mol Biol. 2022;2470:689-713. doi: 10.1007/978-1-0716-2189-9_52
  • 2022-07-27

• Application of B cell immortalization for the isolation of antibodies and B cell clones from vaccine and infection settings

  • Boswell KL, Watkins TA, Cale EM, Samsel J, Andrews SF, Ambrozak DR, Driscoll JI, Messina MA, Narpala S, Hopp CS, Cagigi A, Casazza JP, Yamamoto T, Zhou T, Schief WR, Crompton PD, Ledgerwood JE, Connors M, Gama L, Kwong PD, McDermott A, Mascola JR, Koup RA
  • Front Immunol. 2022 Dec 13;13:1087018. doi: 10.3389/fimmu.2022.1087018
  • 2022-12-13

• Plasmodium falciparum-specific IgM B cells dominate in children, expand with malaria, and produce functional IgM

  • Hopp CS, Sekar P, Diouf A, Miura K, Boswell K, Skinner J, Tipton CM, Peterson ME, Chambers MJ, Andrews S, Lu J, Tan J, Li S, Doumbo S, Kayentao K, Ongoiba A, Traore B, Portugal S, Sun PD, Long C, Koup RA, Long EO, McDermott AB, Crompton PD
  • J Exp Med. 2021 Apr 5;218(4):e20200901. doi: 10.1084/jem.20200901
  • 2021-04-05

• Comparative intravital imaging of human and rodent malaria sporozoites reveals the skin is not a species-specific barrier

  • Hopp CS, Kanatani S, Archer NK, Miller RJ, Liu H, Chiou KK, Miller LS, Sinnis P
  • EMBO Mol Med. 2021 Apr 9;13(4):e11796. doi: 10.15252/emmm.201911796
  • 2021-04-09

• Increased circulation time of Plasmodium falciparum underlies persistent asymptomatic infection in the dry season

  • Andrade CM, Fleckenstein H, Thomson-Luque R, Doumbo S, Lima NF, Anderson C, Hibbert J, Hopp CS, Tran TM, Li S, Niangaly M, Cisse H, Doumtabe D, Skinner J, Sturdevant D, Ricklefs S, Virtaneva K, Asghar M, Homann MV, Turner L, Martins J, Allman EL, N'Dri ME, Winkler V, Llinás M, Lavazec C, Martens C, Färnert A, Kayentao K, Ongoiba A, Lavstsen T, Osório NS, Otto TD, Recker M, Traore B, Crompton PD, Portugal S
  • Nat Med. 2020 Dec;26(12):1929-1940. doi: 10.1038/s41591-020-1084-0
  • 2020-10-26

• Deletion of the rodent malaria ortholog for falcipain-1 highlights differences between hepatic and blood stage merozoites

  • Hopp CS, Bennett BL, Mishra S, Lehmann C, Hanson KK, Lin JW, Rousseau K, Carvalho FA, van der Linden WA, Santos NC, Bogyo M, Khan SM, Heussler V, Sinnis P
  • PLoS Pathog. 2017 Sep 18;13(9):e1006586. doi: 10.1371/journal.ppat.1006586
  • 2017-09-18

• Palmitoyl transferases have critical roles in the development of mosquito and liver stages of Plasmodium

  • Hopp CS, Balaban AE, Bushell ES, Billker O, Rayner JC, Sinnis P
  • Cell Microbiol. 2016 Nov;18(11):1625-1641. doi: 10.1111/cmi.12601
  • 2016-04-16

• Longitudinal analysis of Plasmodium sporozoite motility in the dermis reveals component of blood vessel recognition

  • Hopp CS, Chiou K, Ragheb DR, Salman AM, Khan SM, Liu AJ, Sinnis P
  • Elife. 2015 Aug 13;4:e07789. doi: 10.7554/eLife.07789
  • 2015-08-13

• The innate and adaptive response to mosquito saliva and Plasmodium sporozoites in the skin

  • Hopp CS, Sinnis P
  • Ann N Y Acad Sci. 2015 Apr;1342(1):37-43. doi: 10.1111/nyas.12661
  • 2015-02-18

• Spatiotemporal and functional characterisation of the Plasmodium falciparum cGMP-dependent protein kinase

  • Hopp CS, Flueck C, Solyakov L, Tobin A, Baker DA
  • PLoS One. 2012;7(11):e48206. doi: 10.1371/journal.pone.0048206
  • 2012-11-05