Our publications
2025
Making the most of existing antimalarial medicines: a single dose cure with sulfadoxine-pyrimethamine plus artesunate-pyronaridine.
- Mombo-Ngoma G, Ramharter M, Zoleko Manego R, Lell B, Bassat Q, Aide P, Maiga Ascofare O, Wells TNC, Djimde A, Ntoumi F, Kremsner PG.
- Malar J. 2025 Sep 30;24(1):300. doi: 10.1186/s12936-025-05559-4.
Plasma Proteomics Reveals Distinct Signatures in Occult and Microfilaremic Loa loa Infections.
- Dierks C, Tober-Lau P, Veletzky L, Wang Z, Zühlke B, Ludwig D, Niewienda A, Freiwald A, Bardtke L, Kroneberg P, Stelzl D, Hergeth J, Manego RZ, Mombo-Ngoma G, Agnandji ST, Adegnika AA, Mülleder M, Ramharter M, Ralser M, Kurth F.
- J Infect Dis. 2025 Sep 15;232(3):e383-e392. doi: 10.1093/infdis/jiaf344.
Comparative Analysis of Initial Full Blood Count Parameters in Adults Infected With Plasmodium falciparum for Classification of Disease Severity and Previous Exposure Across Endemic (Gabon) and Nonendemic (Germany) Settings.
- von Wedel C, Matthies LC, Dierks C, Tober-Lau P, Bardtke L, Lingscheid T, Nordmann T, Jochum J, Huebl L, Tappe D, Zoller T, Pechmann K, Okwu DG, Malinga EG, Ralser M, Sander LE, Zoleko-Manego R, Ramharter M, Mombo-Ngoma G, Kurth F, Mischlinger J.
- Open Forum Infect Dis. 2025 Jul 17;12(8):ofaf421. doi: 10.1093/ofid/ofaf421. eCollection 2025 Aug.
A Metabolite-Based Resistance Mechanism Against Malaria.
- Figueiredo A, Rastogi ST, Ramos S, Nogueira F, De Villiers K, de Sousa AGG, Votborg-Novél L, von Wedel C, Tober-Lau P, Jentho E, Pagnotta S, Mesquita M, Cardoso S, Bortolussi G, Muro AF, Tranfield EM, Thibaud J, Duarte D, Sousa AL, Pinto SN, Kitoko J, Mombo-Ngoma G, Mischlinger J, Junttila S, Alenquer M, Amorim MJ, Vasavda C, Bosma PJ, Violante S, Drotleff B, Paixão T, Portugal S, Kurth F, Elo LL, Paul BD, Martins R, Soares MP.
- Science. 2025 Jun 12;388(6752):eadq6741. doi: 10.1126/science.adq6741. Epub 2025 Jun 12.
The Performance of a Rapid Coronavirus Disease 2019 Antigen Test in Rural Gabon.
- Davi SD, Okwu DG, Endamne LR, Hildebrandt TR, Zoleko-Manego R, Mombo-Ngoma G, Agbanrin MD, Adamou R, Adegnika AA, Agnandji ST, Ramharter M, Mischlinger J.
- Am J Trop Med Hyg. 2025 Feb 18;112(5):1052-1059. doi: 10.4269/ajtmh.24-0230. Print 2025 May 7.
The epidemiology of snakebites, treatment-seeking behaviour, and snakebite management in the department of Ogooué et des Lacs, Gabon, Central Africa: a cross-sectional community and health facility-based survey.
- Artus R, Rae J, Hunstig F, Mombo-Ngoma G, Zinsou AH, Okwu DG, Ndoumba WN, Manego RZ, Ramharter M, Lell B, Kremsner PG, Aron MB, Blessmann J, Kreuels B.
- J Glob Health. 2025 Apr 25;15:04062. doi: 10.7189/jogh.15.04062.
The non-artemisinin antimalarial drugs under development: a review.
- Okwu DG, Zoleko Manego R, Duparc S, Kremsner PG, Ramharter M, Mombo-Ngoma G.
- Clin Microbiol Infect. 2025 Jun;31(6):941-947. doi: 10.1016/j.cmi.2025.03.009. Epub 2025 Mar 20.
2024
TKK130 is a 3-Hydroxy-Propanamidine (HPA) with Potent Antimalarial In Vivo Activity and a High Barrier to Resistance
- Knaab TC, Moritz A, Pessanha de Carvalho L, Klein S, Lungerich B, Lohse K, Kruse L, Mombo-Ngoma G, Orta L, Thibaud JL, de Villiers KA, Fidock DA, Burckhardt BB, Held J, Wittlin S, Kurz T.
- J Med Chem. 2025 Jan 9;68(1):95-107. doi: 10.1021/acs.jmedchem.4c01465. Epub 2024 Dec 26.
Non-Invasive Malaria Detection in Sub-Saharan Africa Using a DNA-Based Sensor System.
- Juul-Kristensen T, Thiesen C, Wulff Haurum L, Keller JG, Lendamba RW, Zoleko Manego R, Betouke Ongwe ME, Knudsen BR, Pareja E, Pareja-Tobes E, Labouriau R, Mombo-Ngoma G, Tesauro C.
- Sensors (Basel). 2024 Dec 12;24(24):7947. doi: 10.3390/s24247947.
Undiagnosed AIDS in a 13-year-old boy in rural Gabon.
- Davi SD, Alabi A, Endamne LR, Hildebrandt TR, Lumeka A, Okwu DG, Zoleko-Manego R, Mombo-Ngoma G, Agnandji ST, Ramharter M.
- IDCases. 2024 Oct 23;38:e02103. doi: 10.1016/j.idcr.2024.e02103. eCollection 2024.
Pharmacokinetics of Ganaplacide and Lumefantrine in Adults, Adolescents, and Children with Plasmodium falciparum Malaria Treated with Ganaplacide Plus Lumefantrine Solid Dispersion Formulation: Analysis of Data from a Multinational Phase 2 Study.
- Sangana R, Ogutu B, Yeka A, Kusemererwa S, Tinto H, Toure AO, Kibuuka A, Lingani M, Lourenço C, Mombo-Ngoma G, Nduba V, Landry N'Guessan T, Nassa GJW, Nyantaro M, Tina LO, Anvikar A, Sinha A, Kaguthi G, Fofana B, Grobusch MP, Gaaloul ME, Marrast AC, Pathan R, Chikoto H, Csermak K, Risterucci C, Su G, Winnips C, Zhang J, Zack J.
- J Clin Pharmacol. 2025 Feb;65(2):179-189. doi: 10.1002/jcph.6138. Epub 2024 Sep 29.
Reported healthcare-seeking of loiasis patients and estimation of the associated monetary burden in Gabon: Data from a cross-sectional survey.
- Veletzky L, Schlicker V, Hergeth J, Stelzl DR, Zoleko Manego R, Mombo-Ngoma G, Eberhardt KA, McCall MBB, Adegnika AA, Lell B, Mordmüller B, Adegnika S, Ramharter M, Budke C.
- PLoS Negl Trop Dis. 2024 Aug 19;18(8):e0012389. doi: 10.1371/journal.pntd.0012389. eCollection 2024 Aug.
Recurring Transient Tooth Pain as Newly Described Symptom of Migratory Loiasis: A Mixed-Methods Study in Rural Gabon.
- Hildebrandt TR, Ramharter H, Lumeka Kabwende A, Endamne L, Davi SD, Adegnika AA, Mombo-Ngoma G, Agnandji ST, Mischlinger J, Manego Zoleko R, Ramharter M.
- Am J Trop Med Hyg. 2024 Jul 23;111(4):826-828. doi: 10.4269/ajtmh.24-0059. Print 2024 Oct 2.
Genetic diversity of Plasmodium malariae in sub-Saharan Africa: a two-marker genotyping approach for molecular epidemiological studies.
- Rodi M, Kawecka K, Stephan L, Berner L, Medina MS, Lalremruata A, Woldearegai TG, Matsiegui PB, Groger M, Manego RZ, Ekoka Mbassi D, Mombo-Ngoma G, Agnandji ST, Ramharter M, Mordmüller B, Inoue J, Held J.
- Front Cell Infect Microbiol. 2024 Jul 19;14:1405198. doi: 10.3389/fcimb.2024.1405198. eCollection 2024.
Factors associated with skilled birth attendance in 37 low-income and middle-income countries: a secondary analysis of nationally representative, individual-level data.
- Priebe J, Amuasi J, Dartanto T, Mombo-Ngoma G, Guigas M.
- Lancet Glob Health. 2024 Jul;12(7):e1104-e1110. doi: 10.1016/S2214-109X(24)00145-1.
Dynamics of Plasmodium species and genotype diversity in adults with asymptomatic infection in Gabon.
- Inoue J, Galys A, Rodi M, Ekoka Mbassi D, Mombo-Ngoma G, Adegnika AA, Ramharter M, Zoleko-Manego R, Kremsner PG, Mordmüller B, Held J.
- Int J Infect Dis. 2024 Jun;143:107013. doi: 10.1016/j.ijid.2024.107013. Epub 2024 Mar 16.
Evaluation of knowledge, attitude and practices towards loiasis in the rural community of Sindara, in central African Gabon.
- Hildebrandt TR, Davi SD, Kabwende AL, Endamne LR, Mehmel E, Rakotonirinalalao M, Alabi A, Manego RZ, Kremsner PG, Lell B, Adegnika AA, Mombo-Ngoma G, Mischlinger J, Agnandji ST, Ramharter M.
- PLoS Negl Trop Dis. 2024 May 23;18(5):e0012109. doi: 10.1371/journal.pntd.0012109. eCollection 2024 May.
Eosinophils, basophils and myeloid-derived suppressor cells in chronic Loa loa infection and its treatment in an endemic setting.
- Burger G, Adamou R, Kreuzmair R, Ndoumba WN, Mbassi DE, Mouima AMN, Tabopda CM, Adegnika RM, More A, Okwu DG, Mbadinga LD, Calle CL, Veletzky L, Metzger WG, Mordmüller B, Ramharter M, Mombo-Ngoma G, Adegnika AA, Zoleko-Manego R, McCall MBB.
- PLoS Negl Trop Dis. 2024 May 21;18(5):e0012203. doi: 10.1371/journal.pntd.0012203. eCollection 2024 May.
Plasmodium ovale spp dhfr mutations associated with reduced susceptibility to pyrimethamine in sub-Saharan Africa: a retrospective genetic epidemiology and functional study.
- Joste V, Coppée R, Bailly J, Rakotoarivony Y, Toko Tchokoteu FG, Achache S, Pradines B, Cottrell G, Ariey F, Khim N, Popovici J, Mita T, Groger M, Ramharter M, Egbo T, Juma DW, Akala H, Houzé S, Clain J; Investigation Study Group.
- Lancet Microbe. 2024 Jul;5(7):669-678. doi: 10.1016/S2666-5247(24)00054-5. Epub 2024 May 15.
Assessing the Incidence of Snakebites in Rural Gabon-A Community-Based, Cross-Sectional Pilot Survey.
- Davi SD, Lumeka A, Hildebrandt TR, Endamne LR, Otchague C, Okwu DG, Artus R, Hunstig F, Manego RZ, Blessmann J, Kremsner PG, Lell B, Mombo-Ngoma G, Agnandji ST, Ramharter M, Kreuels B.
- Trop Med Infect Dis. 2024 Mar 23;9(4):68. doi: 10.3390/tropicalmed9040068.
Analysis of diagnostic test outcomes in a large loiasis cohort from an endemic region: Serological tests are often false negative in hyper-microfilaremic infections.
- Veletzky L, Eberhardt KA, Hergeth J, Stelzl DR, Zoleko Manego R, Kreuzmair R, Burger G, Mischlinger J, McCall MBB, Mombo-Ngoma G, Adegnika AA, Agnandji ST, Matsiegui PB, Lell B, Kremsner P, Mordmüller B, Tappe D, Ramharter M.
- PLoS Negl Trop Dis. 2024 Mar 14;18(3):e0012054. doi: 10.1371/journal.pntd.0012054. eCollection 2024 Mar.
The African eye worm: current understanding of the epidemiology, clinical disease, and treatment of loiasis.
- Ramharter M, Butler J, Mombo-Ngoma G, Nordmann T, Davi SD, Zoleko Manego R.
- Lancet Infect Dis. 2024 Mar;24(3):e165-e178. doi: 10.1016/S1473-3099(23)00438-3. Epub 2023 Oct 16.
Safety and efficacy of dihydroartemisinin-piperaquine for intermittent preventive treatment of malaria in pregnant women with HIV from Gabon and Mozambique: a randomised, double-blind, placebo-controlled trial
- González R, Nhampossa T, Mombo-Ngoma G, Mischlinger J, Esen M, Tchouatieu AM, Mendes A, Figueroa-Romero A, Zoleko-Manego R, Lell B, Lagler H, Stoeger L, Dimessa LB, El Gaaloul M, Sanz S, Méndez S, Piqueras M, Sevene E, Ramharter M, Saúte F, Menendez C; MAMAH study group.
- Lancet Infect Dis. 2024 May;24(5):476-487. doi: 10.1016/S1473-3099(23)00738-7. Epub 2024 Jan 12.
2023
Efficacy and safety of ivermectin for the treatment of Plasmodium falciparum infections in asymptomatic male and female Gabonese adults - a pilot randomized, double-blind, placebo-controlled single-centre phase Ib/IIa clinical trial.
- Ekoka Mbassi D, Mombo-Ngoma G, Held J, Okwu DG, Ndzebe-Ndoumba W, Kalkman LC, Ekoka Mbassi FA, Pessanha de Carvalho L, Inoue J, Akinosho MA, Dimessa Mbadinga LB, Yovo EK, Mordmüller B, Kremsner PG, Adegnika AA, Ramharter M, Zoleko-Manego R.
- EBioMedicine. 97:104814.
Community health workers in clinical research at the example of a phase IIIb/ IV antimalarial drug trial conducted in five African countries.
- Groger M, Lutete GT, Assi SB, Bigoga JD, Ntamabyaliro NY, Arbe-Barnes S, Shin J, Adegnika AA, Ntoumi F, Kremsner PG, Ramharter M, Duparc S, Borghini-Fuhrer I, Mombo-Ngoma G.
- Int J Infect Dis. 2023 Dec;137:114-117. doi: 10.1016/j.ijid.2023.10.016. Epub 2023 Oct 21.
The African eye worm: current understanding of the epidemiology, clinical disease, and treatment of loiasis.
- Ramharter M, Butler J, Mombo-Ngoma G, Nordmann T, Davi SD, Zoleko Manego R.
- Lancet Infect Dis. 24(3):e165-e178
Efficacy, safety, and tolerability of albendazole and ivermectin based regimens for the treatment of microfilaraemic loiasis in adult patients in Gabon: A randomized controlled assessor blinded clinical trial
- Zoleko-Manego R, Kreuzmair R, Veletzky L, Ndzebe-Ndoumba W, Ekoka Mbassi D, Okwu DG, Dimessa-Mbadinga-Weyat LB, Houtsa-Temgoua RD, Mischlinger J, McCall MBB, Kresmner PG, Agnandji ST, Lell B, Adegnika AA, Mombo-Ngoma G, Ramharter M
- PLoS Negl Trop Dis. 2023 Aug 28;17(8):e0011584. doi: 10.1371/journal.pntd.0011584
Epidemiology of co-infections in pregnant women living with human immunodeficiency virus 1 in rural Gabon: a cross-sectional study
- Davi SD, Okwu DG, Luetgehetmann M, Abba FM, Aepfelbacher M, Endamne LR, Alabi A, Zoleko-Manego R, Mombo-Ngoma G, Mahmoudou S, Addo MM, Ramharter M, Mischlinger J
- Infect Dis Poverty. 2023 Jul 6;12(1):64. doi: 10.1186/s40249-023-01114-y
Real-life effectiveness of anti-malarial treatment regimens: what are we aiming for?
- Mbassi DE, Pfaffendorf C, Mombo-Ngoma G, Kreuels B, Ramharter M
- Malar J. 2023 Jun 20;22(1):189. doi: 10.1186/s12936-023-04606-2
Ganaplacide (KAF156) plus lumefantrine solid dispersion formulation combination for uncomplicated Plasmodium falciparum malaria: an open-label, multicentre, parallel-group, randomised, controlled, phase 2 trial
- Ogutu B, Yeka A, Kusemererwa S, Thompson R, Tinto H, Toure AO, Uthaisin C, Verma A, Kibuuka A, Lingani M, Lourenço C, Mombo-Ngoma G, Nduba V, N'Guessan TL, Nassa GJW, Nyantaro M, Tina LO, Singh PK, El Gaaloul M, Marrast AC, Chikoto H, Csermak K, Demin I, Mehta D, Pathan R, Risterucci C, Su G, Winnips C, Kaguthi G, Fofana B, Grobusch MP
- Lancet Infect Dis. 2023 Sep;23(9):1051-1061. doi: 10.1016/S1473-3099(23)00209-8
Prevalence of and risk factors for microscopic and submicroscopic malaria infections in pregnancy: a systematic review and meta-analysis
- van Eijk AM, Stepniewska K, Hill J, Taylor SM, Rogerson SJ, Cottrell G, Chico RM, Gutman JR, Tinto H, Unger HW, Yanow SK, Meshnick SR, Ter Kuile FO, Mayor A
- Lancet Glob Health. 2023 Jul;11(7):e1061-e1074. doi: 10.1016/S2214-109X(23)00194-8
Prevalence and impact of SARS-CoV-2 infection on maternal and infant health in African populations: protocol of a multicentre prospective cohort study (MA-CoV project)
- Figueroa-Romero A, Mendes A, Mombo-Ngoma G, Mischlinger J, Esen M, Vogler M, Mazuze M, Mombo-Nzamba L, Mbadinga B, Sanz S, Ramharter M, Saute F, Nhampossa T, Menendez C, González R
- BMJ Open. 2023 May 22;13(5):e067083. doi: 10.1136/bmjopen-2022-067083
Randomized, open-label, phase 2a study to evaluate the contribution of artefenomel to the clinical and parasiticidal activity of artefenomel plus ferroquine in African patients with uncomplicated Plasmodium falciparum malaria
- Gansane A, Lingani M, Yeka A, Nahum A, Bouyou-Akotet M, Mombo-Ngoma G, Kaguthi G, Barceló C, Laurijssens B, Cantalloube C, Macintyre F, Djeriou E, Jessel A, Bejuit R, Demarest H, Marrast AC, Debe S, Tinto H, Kibuuka A, Nahum D, Mawili-Mboumba DP, Zoleko-Manego R, Mugenya I, Olewe F, Duparc S, Ogutu B
- Malar J. 2023 Jan 3;22(1):2. doi: 10.1186/s12936-022-04420-2
2022
Malaria-associated adhesion molecule activation facilitates the destruction of uninfected red blood cells
- Dalimot JJ, Klei TRL, Beuger BM, Dikmen Z, Bouwman SAM, Mombo-Ngoma G, Zoleko-Manego R, Ndzebe-Ndoumba WF, Egée S, Kuijpers TW, Grobusch MP, van Bruggen R
- Blood Adv. 2022 Nov 8;6(21):5798-5810. doi: 10.1182/bloodadvances.2021006171
Erratum to 'In vitro activity of eravacycline, a novel synthetic halogenated tetracycline, against the malaria parasite Plasmodium falciparum' [Journal of Global Antimicrobial Resistance 24 (2021) 93-97]
- Koehne E, Kreidenweiss A, Adegbite BR, Manego RZ, McCall MBB, Mombo-Ngoma G, Adegnika AA, Agnandji ST, Mordmüller B, Held J
- J Glob Antimicrob Resist. 2022 Dec;31:395. doi: 10.1016/j.jgar.2022.10.012
Effectiveness of antimalarial drug combinations in treating concomitant urogenital schistosomiasis in malaria patients in Lambaréné, Gabon: A non-randomised event-monitoring study
- Zoleko-Manego R, Okwu DG, Handrich C, Dimessa-Mbadinga LB, Akinosho MA, Ndzebe-Ndoumba WF, Davi SD, Stelzl D, Veletzky L, Kreidenweiss A, Nordmann T, Adegnika AA, Lell B, Kremsner PG, Ramharter M, Mombo-Ngoma G
- PLoS Negl Trop Dis. 2022 Oct 31;16(10):e0010899. doi: 10.1371/journal.pntd.0010899
Distinct loiasis infection states and associated clinical and hematological manifestations in patients from Gabon
- Veletzky L, Eberhardt KA, Hergeth J, Stelzl DR, Zoleko Manego R, Mombo-Ngoma G, Kreuzmair R, Burger G, Adegnika AA, Agnandji ST, Matsiegui PB, Boussinesq M, Mordmüller B, Ramharter M
- PLoS Negl Trop Dis. 2022 Sep 19;16(9):e0010793. doi: 10.1371/journal.pntd.0010793
Burden of malaria in pregnancy among adolescent girls compared to adult women in 5 sub-Saharan African countries: A secondary individual participant data meta-analysis of 2 clinical trials
- Pons-Duran C, Mombo-Ngoma G, Macete E, Desai M, Kakolwa MA, Zoleko-Manego R, Ouédragou S, Briand V, Valá A, Kabanywanyi AM, Ouma P, Massougbodji A, Sevene E, Cot M, Aponte JJ, Mayor A, Slutsker L, Ramharter M, Menéndez C, González R
- PLoS Med. 2022 Sep 2;19(9):e1004084. doi: 10.1371/journal.pmed.1004084
Performance of Field's Stain Compared with Conventional Giemsa Stain for the Rapid Detection of Blood Microfilariae in Gabon
- Ekoka Mbassi FA, Mombo-Ngoma G, Ndoumba WN, Yovo EK, Eberhardt KA, Ekoka Mbassi D, Adegnika AA, Agnandji ST, Bouyou-Akotet MK, Ramharter M, Zoleko-Manego R
- Am J Trop Med Hyg. 2022 Jul 5;107(2):383-387. doi: 10.4269/ajtmh.22-0061
Correction: Evidence for in vitro and in vivo activity of the antimalarial pyronaridine against Schistosoma
- Koehne E, Zander N, Rodi M, Held J, Hoffmann W, Zoleko-Manego R, Ramharter M, Mombo-Ngoma G, Kremsner PG, Kreidenweiss A
- PLoS Negl Trop Dis. 2022 Jun 2;16(6):e0010512. doi: 10.1371/journal.pntd.0010512
Effectiveness of pyronaridine-artesunate against Plasmodium malariae, Plasmodium ovale spp, and mixed-Plasmodium infections: a post-hoc analysis of the CANTAM-Pyramax trial
- Groger M, Tona Lutete G, Mombo-Ngoma G, Ntamabyaliro NY, Kahunu Mesia G, Muena Mujobu TB, Dimessa Mbadinga LB, Zoleko Manego R, Egger-Adam D, Borghini-Fuhrer I, Shin J, Miller R, Arbe-Barnes S, Duparc S, Ramharter M
- Lancet Microbe. 2022 Aug;3(8):e598-e605. doi: 10.1016/S2666-5247(22)00092-1
Challenges in the clinical development pathway for triple and multiple drug combinations in the treatment of uncomplicated falciparum malaria
- Bassat Q, Maïga-Ascofaré O, May J, Clain J, Mombo-Ngoma G, Groger M, Adegnika AA, Agobé JD, Djimde A, Mischlinger J, Ramharter M
- Malar J. 2022 Feb 22;21(1):61. doi: 10.1186/s12936-022-04079-9
Assessing fetal growth in Africa: Application of the international WHO and INTERGROWTH-21st standards in a Beninese pregnancy cohort
- Yovo E, Accrombessi M, Agbota G, Hocquette A, Atade W, Ladikpo OT, Mehoba M, Degbe A, Mombo-Ngoma G, Massougbodji A, Jackson N, Fievet N, Heude B, Zeitlin J, Briand V
- PLoS One. 2022 Jan 21;17(1):e0262760. doi: 10.1371/journal.pone.0262760
2021
Evaluation of the safety and efficacy of dihydroartemisinin-piperaquine for intermittent preventive treatment of malaria in HIV-infected pregnant women: protocol of a multicentre, two-arm, randomised, placebo-controlled, superiority clinical trial (MAMAH project)
- González R, Nhampossa T, Mombo-Ngoma G, Mischlinger J, Esen M, Tchouatieu AM, Pons-Duran C, Dimessa LB, Lell B, Lagler H, Garcia-Otero L, Zoleko Manego R, El Gaaloul M, Sanz S, Piqueras M, Sevene E, Ramharter M, Saute F, Menendez C
- BMJ Open. 2021 Nov 23;11(11):e053197. doi: 10.1136/bmjopen-2021-053197
A comparison of different scores for diagnosis and mortality prediction of adults with sepsis in Low-and-Middle-Income Countries: a systematic review and meta-analysis
- Adegbite BR, Edoa JR, Ndzebe Ndoumba WF, Dimessa Mbadinga LB, Mombo-Ngoma G, Jacob ST, Rylance J, Hänscheid T, Adegnika AA, Grobusch MP
- EClinicalMedicine. 2021 Oct 30;42:101184. doi: 10.1016/j.eclinm.2021.101184
The Supposedly Innocuous Eye Worm: Or, What Could Make You Put Chili in Your Eye?
- Veletzky L, Mombo-Ngoma G, Ramharter M
- Am J Trop Med Hyg. 2021 Sep 13;105(6):1448-1449. doi: 10.4269/ajtmh.21-0319
Diagnostic performance of capillary and venous blood samples in the detection of Loa loa and Mansonella perstans microfilaraemia using light microscopy
- Mischlinger J, Manego RZ, Mombo-Ngoma G, Ekoka Mbassi D, Hackbarth N, Ekoka Mbassi FA, Davi SD, Kreuzmair R, Veletzky L, Hergeth J, Ndoumba WN, Pitzinger P, Groger M, Matsiegui PB, Adegnika AA, Agnandji ST, Lell B, Ramharter M
- PLoS Negl Trop Dis. 2021 Aug 16;15(8):e0009623. doi: 10.1371/journal.pntd.0009623
Evidence for in vitro and in vivo activity of the antimalarial pyronaridine against Schistosoma
- Koehne E, Zander N, Rodi M, Held J, Hoffmann W, Zoleko-Manego R, Ramharter M, Mombo-Ngoma G, Kremsner PG, Kreidenweiss A
- PLoS Negl Trop Dis. 2021 Jun 24;15(6):e0009511. doi: 10.1371/journal.pntd.0009511
Pyronaridine-artesunate real-world safety, tolerability, and effectiveness in malaria patients in 5 African countries: A single-arm, open-label, cohort event monitoring study
- Tona Lutete G, Mombo-Ngoma G, Assi SB, Bigoga JD, Koukouikila-Koussounda F, Ntamabyaliro NY, Ntoumi F, Agnandji ST, Groger M, Shin J, Borghini-Fuhrer I, Arbe-Barnes S, Allen SJ, Kremsner PG, Miller R, Duparc S, Ramharter M
- PLoS Med. 2021 Jun 15;18(6):e1003669. doi: 10.1371/journal.pmed.1003669
Point-of-care ultrasound to assess volume status and pulmonary oedema in malaria patients
- Pugliese CM, Adegbite BR, Edoa JR, Mombo-Ngoma G, Obone-Atome FA, Heuvelings CC, Bélard S, Kalkman LC, Leopold SJ, Hänscheid T, Adegnika AA, Huson MA, Grobusch MP
- Infection. 2022 Feb;50(1):65-82. doi: 10.1007/s15010-021-01637-2
Exploratory analysis of the effect of helminth infection on the immunogenicity and efficacy of the asexual blood-stage malaria vaccine candidate GMZ2
- Nouatin O, Mengue JB, Dejon-Agobé JC, Fendel R, Ibáñez J, Ngoa UA, Edoa JR, Adégbité BR, Honkpéhédji YJ, Zinsou JF, Hounkpatin AB, Moutairou K, Homoet A, Esen M, Kreidenweiss A, Hoffman SL, Theisen M, Luty AJF, Lell B, Agnandji ST, Mombo-Ngoma G, Ramharter M, Kremsner P, Mordmüller B, Adegnika AA
- PLoS Negl Trop Dis. 2021 Jun 1;15(6):e0009361. doi: 10.1371/journal.pntd.0009361
A randomized, double-blind, phase 2b study to investigate the efficacy, safety, tolerability and pharmacokinetics of a single-dose regimen of ferroquine with artefenomel in adults and children with uncomplicated Plasmodium falciparum malaria
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