Unsere Publikationen auf einen Blick
2023
Structural and functional characterization of the Sin Nombre virus L protein
- Meier K, Thorkelsson SR, Durieux Trouilleton Q, Vogel D, Yu D, Kosinski J, Cusack S, Malet H, Grünewald K, Quemin ERJ, Rosenthal M.
- PLoS Pathog. 2023 Aug 7;19(8):e1011533. doi: 10.1371/journal.ppat.1011533. eCollection 2023 Aug.
A validated protocol to UV-inactivate SARS-CoV-2 and herpesvirus-infected cells.
- Soh TK, Pfefferle S, Wurr S, von Possel R, Oestereich L, Rieger T, Uetrecht C, Rosenthal M*, Bosse JB*.
- PLoS One. 2023 May 10;18(5):e0274065. doi: 10.1371/journal.pone.0274065. eCollection 2023.
Structural insights into viral genome replication by the severe fever with thrombocytopenia syndrome virus L protein
- Williams HM, Thorkelsson SR, Vogel D, Milewski M, Busch C, Cusack S, Grünewald K, Quemin ERJ, Rosenthal M.
- Nucleic Acids Res. 51(3):1424-1442
An RNA to rule them all: Critical steps in Lassa virus ribonucleoparticle assembly and recruitment
- Sänger L, Williams HM, Yu D, Vogel D, Kosinski J, Rosenthal M*, Uetrecht C*
- BioRxiv Preprint
The mechanism of genome replication and transcription in bunyaviruses.
- Malet H, Williams HM, Cusack S, Rosenthal M.
- PLoS Pathog. 2023 Jan 12;19(1):e1011060. doi: 10.1371/journal.ppat.1011060.
AlphaPulldown – a Python package for protein-protein interaction screens using AlphaFold-Multimer.
- Yu D, Chojnowski G, Rosenthal M, Kosinski J.
- Bioinformatics. 2023 Jan 1;39(1):btac749. doi: 10.1093/bioinformatics/btac749.
2021
Conformational changes in Lassa virus L protein associated with promoter binding and RNA synthesis activity.
- Kouba T*, Vogel D*, Thorkelsson SR*, Quemin ERJ, Williams HM, Milewski M, Busch C, Günther S, Grünewald K, Rosenthal M#, Cusack S#. |Note: * equal contributing first authors, # equal contributing senior authors & co-corresponding authors
- Nat Commun. 2021 Dec 2;12(1):7018. doi: 10.1038/s41467-021-27305-5.
Hantavirus Replication Cycle – An Updated Structural Virology Perspective.
- Meier K, Thorkelsson SR, Quemin E*, Rosenthal M*
- Viruses
Errors in the deposited SFTSV L protein structure.
- Cusack S, Rosenthal M.
- Nat Microbiol. 2021 May;6(5):549-550. doi: 10.1038/s41564-021-00901-3.
Reduced Nucleoprotein Availability Impairs Negative-Sense RNA Virus Replication and Promotes Host Recognition.
- Nilsson-Payant BE, Blanco-Melo D, Uhl S, Escudero-Pérez B, Olschewski S, Thibault P, Panis M, Rosenthal M, Muñoz-Fontela C, Lee B, tenOever BR.
- J Virol. 2021 Apr 12;95(9):e02274-20. doi: 10.1128/JVI.02274-20.
2020
Structural and functional characterization of the severe fever with thrombocytopenia syndrome virus L protein
- Vogel D, Thorkelsson SR, Quemin ERJ, Meier K, Kouba T, Gogrefe N, Busch C, Reindl S, Günther S, Cusack S, Grünewald K, Rosenthal M
- Nucleic Acids Res. 48(10):5749-5765
The Cap-Snatching Mechanism of Bunyaviruses
- Olschewski S, Cusack S, Rosenthal M
- Trends Microbiol. 28(4):293-303
2019
Structure and function of the Toscana virus cap-snatching endonuclease.
- Jones R, Lessoued S, Meier K, Devignot S, Barata-García S, Mate M, Bragagnolo G, Weber F, Rosenthal M, Reguera J.
- Nucleic Acids Res. 2019 Oct 4. pii: gkz838. doi: 10.1093/nar/gkz838. [Epub ahead of print] PubMed PMID: 31584100.
Rift Valley fever virus minigenome system for investigating the role of L protein residues in viral transcription and replication.
- Jérôme H, Rudolf M, Lelke M, Pahlmann M, Busch C, Bockholt S, Wurr S, Günther S, Rosenthal M, Kerber R.
- J Gen Virol. 2019 Jun 6. doi: 10.1099/jgv.0.001281.
Structure of a functional cap-binding domain in Rift Valley fever virus L protein.
- Gogrefe N, Reindl S, Günther S, Rosenthal M.
- PLoS Pathog. 2019 May 28;15(5):e1007829. doi: 10.1371/journal.ppat.1007829.
Biochemical characterization of the Lassa virus L protein.
- Vogel D, Rosenthal M, Gogrefe N, Reindl S, Günther S.
- J Biol Chem. 2019 Mar 29. pii: jbc.RA118.006973. doi: 10.1074/jbc.RA118.006973. [Epub ahead of print]
2018
Biochemical and structural studies reveal differences and commonalities among cap-snatching endonucleases from segmented negative-strand RNA viruses.
- Holm T, Kopicki JD, Busch C, Olschewski S, Rosenthal M, Uetrecht C, Günther S, Reindl S.
- J Biol Chem. 2018 Oct 22. pii: jbc.RA118.004373. doi: 10.1074/jbc.RA118.004373.
Role of the C Terminus of Lassa Virus L Protein in Viral mRNA Synthesis.
- Lehmann M, Pahlmann M, Jerome H, Busch C, Lelke M, Günther S.
- J Virol. 2014 Aug;88(15):8713-7. doi: 10.1128/JVI.00652-14.
Occupation-Associated Fatal Limbic Encephalitis Caused by Variegated Squirrel Bornavirus 1, Germany, 2013.
- Tappe D, Schlottau K, Cadar D, Hoffmann B, Balke L, Bewig B, Hoffmann D, Eisermann P, Fickenscher H, Krumbholz A, Laufs H, Huhndorf M, Rosenthal M, Schulz-Schaeffer W, Ismer G, Hotop SK, Brönstrup M, Ott A, Schmidt-Chanasit J, Beer M.
- Emerg Infect Dis. 2018 Jun;24(6):978-987. doi: 10.3201/eid2406.172027.
2017
Structural insights into reptarenavirus cap-snatching machinery
- Rosenthal M, Gogrefe N, Vogel D, Reguera J, Rauschenberger B, Cusack S, Günther S, Reindl S
- PLoS Pathog. 13(5):e1006400
2016
Comparative Structural and Functional Analysis of Bunyavirus and Arenavirus Cap-Snatching Endonucleases.
- Reguera J, Gerlach P, Rosenthal M, Gaudon S, Coscia F, Günther S, Cusack S.
- PLoS Pathog. 2016 Jun 15;12(6):e1005636.
Atomic Structure and Biochemical Characterization of an RNA Endonuclease in the N Terminus of Andes Virus L Protein.
- Fernández-García Y, Reguera J, Busch C, Witte G, Sánchez-Ramos O, Betzel C, Cusack S, Günther S, Reindl S.
- PLoS Pathog. 2016 Jun 14;12(6):e1005635.
2015
Surveillance of Batai virus in bovines from Germany.
- Hofmann M, Wiethölter A, Blaha I, Jöst H, Heinemann P, Lehmann M, Miller T, Cadar D, Yanase T, Kley N, Eiden M, Groschup M, Schmidt-Chanasit J.
- Clin Vaccine Immunol. 2015 Jun;22(6):672-3. doi: 10.1128/CVI.00082-15.
2014
Evaluation of antiviral efficacy of ribavirin, arbidol, and T-705 (favipiravir) in a mouse model for Crimean-Congo hemorrhagic fever.
- Oestereich L, Rieger T, Neumann M, Bernreuther C, Lehmann M, Krasemann S, Wurr S, Emmerich P, de Lamballerie X, Ölschläger S, Günther S.
- PLoS Negl Trop Dis. 2014 May 1;8(5):e2804. doi: 10.1371/journal.pntd.0002804.
2013
The role of oligomerization for the biological functions of the arenavirus nucleoprotein.
- Lennartz F, Hoenen T, Lehmann M, Groseth A, Garten W.
- Arch Virol. 2013 Sep;158(9):1895-905. doi: 10.1007/s00705-013-1684-9.