Unsere Publikationen auf einen Blick

• 2023

  • Structural and functional characterization of the Sin Nombre virus L protein

    • Meier K, Thorkelsson SR, Durieux Trouilleton Q, Vogel D, Yu D, Kosinski J, Cusack S, Malet H, Grünewald K, Quemin ERJ, Rosenthal M.
    • PLoS Pathog. 2023 Aug 7;19(8):e1011533. doi: 10.1371/journal.ppat.1011533. eCollection 2023 Aug.
    • 2023-08-07

  • A validated protocol to UV-inactivate SARS-CoV-2 and herpesvirus-infected cells.

    • Soh TK, Pfefferle S, Wurr S, von Possel R, Oestereich L, Rieger T, Uetrecht C, Rosenthal M*, Bosse JB*.
    • PLoS One. 2023 May 10;18(5):e0274065. doi: 10.1371/journal.pone.0274065. eCollection 2023.
    • 2023-05-10

  • Structural insights into viral genome replication by the severe fever with thrombocytopenia syndrome virus L protein

    • Williams HM, Thorkelsson SR, Vogel D, Milewski M, Busch C, Cusack S, Grünewald K, Quemin ERJ, Rosenthal M.
    • Nucleic Acids Res. 51(3):1424-1442
    • 2023-02-22

  • An RNA to rule them all: Critical steps in Lassa virus ribonucleoparticle assembly and recruitment

    • Sänger L, Williams HM, Yu D, Vogel D, Kosinski J, Rosenthal M*, Uetrecht C*
    • BioRxiv Preprint
    • 2023-02-09

  • The mechanism of genome replication and transcription in bunyaviruses.

    • Malet H, Williams HM, Cusack S, Rosenthal M.
    • PLoS Pathog. 2023 Jan 12;19(1):e1011060. doi: 10.1371/journal.ppat.1011060.
    • 2023-01-12

  • AlphaPulldown – a Python package for protein-protein interaction screens using AlphaFold-Multimer.

    • Yu D, Chojnowski G, Rosenthal M, Kosinski J.
    • Bioinformatics. 2023 Jan 1;39(1):btac749. doi: 10.1093/bioinformatics/btac749.
    • 2023-01-01

• 2021

  • Conformational changes in Lassa virus L protein associated with promoter binding and RNA synthesis activity.

    • Kouba T*, Vogel D*, Thorkelsson SR*, Quemin ERJ, Williams HM, Milewski M, Busch C, Günther S, Grünewald K, Rosenthal M#, Cusack S#. |Note: * equal contributing first authors, # equal contributing senior authors & co-corresponding authors
    • Nat Commun. 2021 Dec 2;12(1):7018. doi: 10.1038/s41467-021-27305-5.
    • 2021-12-02

  • Hantavirus Replication Cycle – An Updated Structural Virology Perspective.

    • Meier K, Thorkelsson SR, Quemin E*, Rosenthal M*
    • Viruses
    • 2021-08-06

  • Errors in the deposited SFTSV L protein structure.

    • Cusack S, Rosenthal M.
    • Nat Microbiol. 2021 May;6(5):549-550. doi: 10.1038/s41564-021-00901-3.
    • 2021-05-06

  • Reduced Nucleoprotein Availability Impairs Negative-Sense RNA Virus Replication and Promotes Host Recognition.

    • Nilsson-Payant BE, Blanco-Melo D, Uhl S, Escudero-Pérez B, Olschewski S, Thibault P, Panis M, Rosenthal M, Muñoz-Fontela C, Lee B, tenOever BR.
    • J Virol. 2021 Apr 12;95(9):e02274-20. doi: 10.1128/JVI.02274-20.
    • 2021-04-12

• 2020

  • Structural and functional characterization of the severe fever with thrombocytopenia syndrome virus L protein

    • Vogel D, Thorkelsson SR, Quemin ERJ, Meier K, Kouba T, Gogrefe N, Busch C, Reindl S, Günther S, Cusack S, Grünewald K, Rosenthal M
    • Nucleic Acids Res. 48(10):5749-5765
    • 2020-06-04

  • The Cap-Snatching Mechanism of Bunyaviruses

    • Olschewski S, Cusack S, Rosenthal M
    • Trends Microbiol. 28(4):293-303
    • 2020-04-01

• 2019

  • Structure and function of the Toscana virus cap-snatching endonuclease.

    • Jones R, Lessoued S, Meier K, Devignot S, Barata-García S, Mate M, Bragagnolo G, Weber F, Rosenthal M, Reguera J.
    • Nucleic Acids Res. 2019 Oct 4. pii: gkz838. doi: 10.1093/nar/gkz838. [Epub ahead of print] PubMed PMID: 31584100.
    • 2019-10-04

  • Rift Valley fever virus minigenome system for investigating the role of L protein residues in viral transcription and replication.

    • Jérôme H, Rudolf M, Lelke M, Pahlmann M, Busch C, Bockholt S, Wurr S, Günther S, Rosenthal M, Kerber R.
    • J Gen Virol. 2019 Jun 6. doi: 10.1099/jgv.0.001281.
    • 2019-06-06

  • Structure of a functional cap-binding domain in Rift Valley fever virus L protein.

    • Gogrefe N, Reindl S, Günther S, Rosenthal M.
    • PLoS Pathog. 2019 May 28;15(5):e1007829. doi: 10.1371/journal.ppat.1007829.
    • 2019-05-28

  • Biochemical characterization of the Lassa virus L protein.

    • Vogel D, Rosenthal M, Gogrefe N, Reindl S, Günther S.
    • J Biol Chem. 2019 Mar 29. pii: jbc.RA118.006973. doi: 10.1074/jbc.RA118.006973. [Epub ahead of print]
    • 2019-03-29

• 2018

  • Biochemical and structural studies reveal differences and commonalities among cap-snatching endonucleases from segmented negative-strand RNA viruses.

    • Holm T, Kopicki JD, Busch C, Olschewski S, Rosenthal M, Uetrecht C, Günther S, Reindl S.
    • J Biol Chem. 2018 Oct 22. pii: jbc.RA118.004373. doi: 10.1074/jbc.RA118.004373.
    • 2018-10-22

  • Role of the C Terminus of Lassa Virus L Protein in Viral mRNA Synthesis.

    • Lehmann M, Pahlmann M, Jerome H, Busch C, Lelke M, Günther S.
    • J Virol. 2014 Aug;88(15):8713-7. doi: 10.1128/JVI.00652-14.
    • 2018-08-15

  • Occupation-Associated Fatal Limbic Encephalitis Caused by Variegated Squirrel Bornavirus 1, Germany, 2013.

    • Tappe D, Schlottau K, Cadar D, Hoffmann B, Balke L, Bewig B, Hoffmann D, Eisermann P, Fickenscher H, Krumbholz A, Laufs H, Huhndorf M, Rosenthal M, Schulz-Schaeffer W, Ismer G, Hotop SK, Brönstrup M, Ott A, Schmidt-Chanasit J, Beer M.
    • Emerg Infect Dis. 2018 Jun;24(6):978-987. doi: 10.3201/eid2406.172027.
    • 2018-06-24

• 2017

  • Structural insights into reptarenavirus cap-snatching machinery

    • Rosenthal M, Gogrefe N, Vogel D, Reguera J, Rauschenberger B, Cusack S, Günther S, Reindl S
    • PLoS Pathog. 13(5):e1006400
    • 2017-05-15

• 2016

  • Comparative Structural and Functional Analysis of Bunyavirus and Arenavirus Cap-Snatching Endonucleases.

    • Reguera J, Gerlach P, Rosenthal M, Gaudon S, Coscia F, Günther S, Cusack S.
    • PLoS Pathog. 2016 Jun 15;12(6):e1005636.
    • 2016-06-15

  • Atomic Structure and Biochemical Characterization of an RNA Endonuclease in the N Terminus of Andes Virus L Protein.

    • Fernández-García Y, Reguera J, Busch C, Witte G, Sánchez-Ramos O, Betzel C, Cusack S, Günther S, Reindl S.
    • PLoS Pathog. 2016 Jun 14;12(6):e1005635.
    • 2016-06-14

• 2015

  • Surveillance of Batai virus in bovines from Germany.

    • Hofmann M, Wiethölter A, Blaha I, Jöst H, Heinemann P, Lehmann M, Miller T, Cadar D, Yanase T, Kley N, Eiden M, Groschup M, Schmidt-Chanasit J.
    • Clin Vaccine Immunol. 2015 Jun;22(6):672-3. doi: 10.1128/CVI.00082-15.
    • 2015-06-22

• 2014

  • Evaluation of antiviral efficacy of ribavirin, arbidol, and T-705 (favipiravir) in a mouse model for Crimean-Congo hemorrhagic fever.

    • Oestereich L, Rieger T, Neumann M, Bernreuther C, Lehmann M, Krasemann S, Wurr S, Emmerich P, de Lamballerie X, Ölschläger S, Günther S.
    • PLoS Negl Trop Dis. 2014 May 1;8(5):e2804. doi: 10.1371/journal.pntd.0002804.
    • 2014-05-01

• 2013

  • The role of oligomerization for the biological functions of the arenavirus nucleoprotein.

    • Lennartz F, Hoenen T, Lehmann M, Groseth A, Garten W.
    • Arch Virol. 2013 Sep;158(9):1895-905. doi: 10.1007/s00705-013-1684-9.
    • 2013-06-15