Publications

Publication Highlights

The C-type lectin receptor MINCLE interferes with eosinophil function and protective intestinal immunity in Strongyloides ratti-infected mice
- Lara Linnemann, Jennifer Antwi-Ekwuruke, Vinayaga Gnanapragassam, Corinna Bang, Malte Rühlemann, Jürgen Ruland, Wiebke Hartmann, Lennart Heepmann, Sara Dörken, Saleh M. Yunus, Birte Viebrock, Annette Schlosser, Bernd Lepenies, Minka Breloer
- Mucosal Immunology
- 2025-02-01
Strongyloides ratti infection in mice: immune response and immune modulation
- Minka Breloer, Lara Linnemann
- Phil. Trans. R. Soc. B3792022044020220440 http://doi.org/10.1098/rstb.2022.0440
- 2023-11-27
Filarial infections compromise influenza vaccination efficacy: lessons from the mouse
- Breloer M, Hartmann W
- Immunology Letters. 2023 Mar:255:62-66. doi: 10.1016/j.imlet.2023.03.001
- 2023-03-06
Retinoic acid drives intestine-specific adaptation of effector ILC2s originating from distant sites
- Shaikh N, Waterhölter A, Gnirck AC, Becker M, Adamiak V, Henneken L, Wunderlich M, Hartmann W, Linnemann L, Huber TB, Krebs CF, Panzer U, Locksley RM, Wilhelm C, Breloer M, Turner JE
- J Exp Med. 2023 Dec 4;220(12):e20221015. doi: 10.1084/jem.20221015
- 2023-09-12
Eosinophils and neutrophils eliminate migrating Strongyloides ratti larvae at the site of infection in the context of extracellular DNA trap formation
- Ehrens A, Rüdiger N, Heepmann L, Linnemann L, Hartmann W, Hübner M, Breloer M
- Front. Immunol. 12 August 2021 | https://doi.org/10.3389/fimmu.2021.715766
- 2021-08-12
IL-33-facilitates rapid expulsion of the parasitic nematode Strongyloides ratti from the intestine via ILC2- and IL-9-driven mast cell activation
- Meiners J, Reitz M, Rüdiger N, Turner JE, Heepmann L, Rudolf L, Hartmann W. McSorley HJ, Breloer M
- PLoS Pathog. 2020 Dec 22;16(12):e1009121. doi: 10.1371/journal.ppat.1009121
- 2020-12-22
Helminth infections suppress the efficacy of vaccination against seasonal influenza
- Hartmann W, Brunn M-L, Stetter N, Gagliani N, Muskate F, Stanelle-Bertram S, Gabriel G, Breloer M
- Cell Reports. 2019 Nov 19;29(8):2243-2256.e4. doi: 10.1016/j.celrep.2019.10.051
- 2019-11-19
Rbpj expression in regulatory T cells is critical for restraining TH2 responses
- Delacher M, Schmidl C, Herzig Y, Breloer M, Hartman W, Brunk F, Kägebein D, Träger U, Hofer A-C, Weichenhan D, Imbusch C, Hotz-Wagenblatt A, Hielscher T, Breiling A, Federico G, Groene H-J, Schmid R, Rehli M, Abramson J, Feuerer M, Bittner S
- Nature Communications. 2019 Apr 8;10(1):1621. doi: 10.1038/s41467-019-09276-w
- 2019-04-08
Mucosal mast cells are indispensable for the timely termination of Strongyloides ratti infection
- Reitz M, Brunn ML, Rodewald HR, Feyerabend TB, Roers A, Dudeck A, Voehringer D, Jönsson F, Kühl AA, Breloer M
- Mucosal Immunol. 2017 Mar;10(2):481-492. doi: 10.1038/mi.2016.56
- 2016-05-25
Cutting Edge: The BTLA-HVEM Regulatory Pathway Interferes with Protective Immunity to Intestinal Helminth Infection
- Breloer M, Hartmann W, Blankenhaus B, Eschbach ML, Pfeffer K, Jacobs T
- Journal of Immunology. 2015 Feb 15;194(4):1413-6. doi: 10.4049/jimmunol.1402510
- 2015-01-16
Foxp3+ regulatory T cells delay expulsion of intestinal nematodes by suppression of IL-9-driven mast cell activation in BALB/c but not in C57BL/6 mice
- Blankenhaus B, Reitz M, Brenz Y, Eschbach ML, Hartmann W, Haben I, Sparwasser T, Huehn J, Kühl A, Feyerabend TB, Rodewald HR, Breloer M
- PLoS pathogens. 2014 Feb 6;10(2):e1003913. doi: 10.1371/journal.ppat.1003913
- 2014-02-06

Scientific publications by year

2025
- Interdisciplinary symposium on challenges and opportunities for vaccines: A comprehensive approach of current and future vaccine strategies to improve vaccine effectiveness in complex chronic infectious contexts
  - Alex S. Siebner, Marrium Habib, Vanesa Osmani, Ayola Akim Adegnika, Christian Bogdan, Minka Breloer, Alison Elliott, Anahita Fathi, Greet Hendrickx, Justin Komguep Nono, Roland Lang, Johannes U. Mayer, Benjamin Mordmüller, Esther Ndungo, Ulrike Protzer, Maria Yazdanbakhsh, Stefanie J. Klug, Clarissa Prazeres da Costa, Meral Esen
  - Vaccine: X
  - 2025-03-01
- The C-type lectin receptor MINCLE interferes with eosinophil function and protective intestinal immunity in Strongyloides ratti-infected mice
  - Lara Linnemann, Jennifer Antwi-Ekwuruke, Vinayaga Gnanapragassam, Corinna Bang, Malte Rühlemann, Jürgen Ruland, Wiebke Hartmann, Lennart Heepmann, Sara Dörken, Saleh M. Yunus, Birte Viebrock, Annette Schlosser, Bernd Lepenies, Minka Breloer
  - Mucosal Immunology
  - 2025-02-01
- Experimental Infection of Mice with the Parasitic Nematode Strongyloides ratti
  - Sara Dörken, Kira Duhm, Birte Viebrock, Lara Linnemann, Lennart Heepmann, Wiebke Hartmann, Jennifer Antwi-Ekwuruke, M. Saleh Yunus, Minka Breloer
  - Immunology and Infection
  - 2025-01-17
2024
- Immunological clues to sex differences in parasitic diseases
  - Julie Sellau, Charlotte Sophie Hansen, Rosa Isela Gálvez, Lara Linnemann, Barbara Honecker, Hanna Lotter
  - Trends in Parasitology
  - 2024-11-01
- Evaluating alternative compounds for strongyloidiasis therapy: Novel insights from larval migration inhibition test
  - María Cambra-Pellejà, Elora Valderas-García, Rafael Balaña-Fouce, Jennifer de la Vega, Esther del Olmo, Jennifer Antwi-Ekwuruke, Lara Linnemann, Lennart Heepmann, Minka Breloer, María Martínez-Valladares
  - PLOS Neglected Tropical Diseases
  - 2024-10-07
2023
- Strongyloides ratti infection in mice: immune response and immune modulation
  - Minka Breloer, Lara Linnemann
  - Phil. Trans. R. Soc. B3792022044020220440 http://doi.org/10.1098/rstb.2022.0440
  - 2023-11-27
- Retinoic acid drives intestine-specific adaptation of effector ILC2s originating from distant sites
  - Shaikh N, Waterhölter A, Gnirck AC, Becker M, Adamiak V, Henneken L, Wunderlich M, Hartmann W, Linnemann L, Huber TB, Krebs CF, Panzer U, Locksley RM, Wilhelm C, Breloer M, Turner JE
  - J Exp Med. 2023 Dec 4;220(12):e20221015. doi: 10.1084/jem.20221015
  - 2023-09-12
- IRF4 is required for migration of CD4+ T cells to the intestine but not for Th2 and Th17 cell maintenance
  - Schmidt C, Harberts A, Reimers D, Bertram T, Voß LC, Schmid J, Lory NC, Spohn M, Koch-Nolte F, Huber S, Raczkowski F, Breloer M, Mittrücker HW
  - Front. Immunol. 2023 Jul 3;14:1182502. doi: 10.3389/fimmu.2023.1182502
  - 2023-07-03
- Filarial infections compromise influenza vaccination efficacy: lessons from the mouse
  - Breloer M, Hartmann W
  - Immunology Letters. 2023 Mar:255:62-66. doi: 10.1016/j.imlet.2023.03.001
  - 2023-03-06
2022
- Pre-existing helminth infection impairs the efficacy of adjuvanted influenza vaccination in mice
  - Hartmann W, Brunn ML, Stetter N, Gabriel G, Breloer M
  - PLoS One. 2022 Mar 31;17(3):e0266456. doi: 10.1371/journal.pone.0266456
  - 2022-03-31
2021
- A combination of deworming and prime-boost vaccination regimen restores efficacy of vaccination against influenza in helminth-infected mice
  - Stetter N, Hartmann W, Brunn ML, Stanelle-Bertram S, Gabriel G, Breloer M
  - Front. Immunol., 21 December 2021 | https://doi.org/10.3389/fimmu.2021.784141
  - 2021-12-21
- Eosinophils and neutrophils eliminate migrating Strongyloides ratti larvae at the site of infection in the context of extracellular DNA trap formation
  - Ehrens A, Rüdiger N, Heepmann L, Linnemann L, Hartmann W, Hübner M, Breloer M
  - Front. Immunol. 12 August 2021 | https://doi.org/10.3389/fimmu.2021.715766
  - 2021-08-12
- Elucidating different pattern of immunoregulation in BALB/c and C57BL/6 mice and their F1 progeny
  - Hartmann W, Blankenhaus B, Brunn ML, Meiners J, Breloer M
  - Sci Rep. 2021 Jan 15;11(1):1536. doi: 10.1038/s41598-020-79477-7
  - 2021-01-15
2020
- IL-33-facilitates rapid expulsion of the parasitic nematode Strongyloides ratti from the intestine via ILC2- and IL-9-driven mast cell activation
  - Meiners J, Reitz M, Rüdiger N, Turner JE, Heepmann L, Rudolf L, Hartmann W. McSorley HJ, Breloer M
  - PLoS Pathog. 2020 Dec 22;16(12):e1009121. doi: 10.1371/journal.ppat.1009121
  - 2020-12-22
- Limited role of mast cells during infection with the parasitic nematode Litomosoides sigmodontis
  - Linnemann LC, Reitz M, Feyerabend TB, Breloer M, Hartmann W
  - PLoS Neglected Tropical Diseases. 2020 Jul 31;14(7):e0008534. doi: 10.1371/journal.pntd.0008534
  - 2020-07-31
2019
- Helminth infections suppress the efficacy of vaccination against seasonal influenza
  - Hartmann W, Brunn M-L, Stetter N, Gagliani N, Muskate F, Stanelle-Bertram S, Gabriel G, Breloer M
  - Cell Reports. 2019 Nov 19;29(8):2243-2256.e4. doi: 10.1016/j.celrep.2019.10.051
  - 2019-11-19
- Rbpj expression in regulatory T cells is critical for restraining TH2 responses
  - Delacher M, Schmidl C, Herzig Y, Breloer M, Hartman W, Brunk F, Kägebein D, Träger U, Hofer A-C, Weichenhan D, Imbusch C, Hotz-Wagenblatt A, Hielscher T, Breiling A, Federico G, Groene H-J, Schmid R, Rehli M, Abramson J, Feuerer M, Bittner S
  - Nature Communications. 2019 Apr 8;10(1):1621. doi: 10.1038/s41467-019-09276-w
  - 2019-04-08
2018
- Basophils are dispensable for the establishment of protective adaptive immunity against primary and challenge infection with the intestinal helminth parasite Strongyloides ratti
  - Reitz M, Brunn M-L, Voehringer D, M Breloer
  - PLoS Neglected Tropical Diseases. 2018 12(11):e0006992. doi: 10.1371/journal.pntd.0006992.
  - 2018-11-29
- Basophils are dispensable for the control of a filarial infection
  - Hartmann W, Linnemann L C, Reitz M, Specht S, Voehringer D, M Breloer
  - ImmunoHorizons. 2018 Sep 26;2(8):296-304. doi: 10.4049/immunohorizons.1800018
  - 2018-09-01
- Interleukin-9 promotes early mast cell-mediated expulsion of Strongyloides ratti but is dispensable for generation of protective memory
  - Reitz M, Hartmann W, Rüdiger N, Orinska Z, Brunn ML, Minka Breloer
  - Scientific Reports. 2018 Jun 5;8(1):8636. doi: 10.1038/s41598-018-26907-2
  - 2018-06-05
2017
- Th2/1 Hybrid Cells Occurring in Murine and Human Strongyloidiasis Share Effector Functions of Th1 Cells
  - Bock CN, Babu S, Breloer M, Rajamanickam A, Boothra Y, Brunn ML, Kühl AA, Merle R, Löhning M, Hartmann S, Rausch S
  - Front Cell Infect Microbiol. 2017 Jun 20:7:261. doi: 10.3389/fcimb.2017.00261
  - 2017-06-20
2016
- Filariae-retrovirus co-infection in mice is associated with suppressed virus-specific IgG immune response and higher viral loads
  - Dietze KK, Dittmer U, Koudaimi DK, Schimmer S, Reitz M, Breloer M*, Hartmann W*
  - PLoS Neglected Tropical Diseases. 2016 Dec 6;10(12):e0005170. doi: 10.1371/journal.pntd.0005170
  - 2016-12-06
- Mucosal mast cells are indispensable for the timely termination of Strongyloides ratti infection
  - Reitz M, Brunn ML, Rodewald HR, Feyerabend TB, Roers A, Dudeck A, Voehringer D, Jönsson F, Kühl AA, Breloer M
  - Mucosal Immunol. 2017 Mar;10(2):481-492. doi: 10.1038/mi.2016.56
  - 2016-05-25
- Strongyloides infection in rodents: immune response and immune regulation
  - Breloer M, Abraham D
  - Parasitology. 2017 Mar;144(3):295-315. doi: 10.1017/S0031182016000111
  - 2016-01-15
2015
- Anti-CD83 promotes IgG1 isotype switch in marginal zone B cells in response to TI-2 antigen
  - Kretschmer B, Weber J, Hutloff A, Fleischer B, Breloer M, Osterloh A
  - Immunobiology 2015 Aug;220(8):964-75. doi: 10.1016/j.imbio.2015.02.008
  - 2015-08-15
- Litomosoides sigmodontis induces TGF-beta receptor responsive, IL-10-producing T cells that suppress bystander T-cell proliferation in mice
  - Hartmann W, Schramm C, Breloer, M
  - European Journal of Immunology. 2015 Sep;45(9):2568-81. doi: 10.1002/eji.201545503.
  - 2015-07-03
- Protein kinase CK2 enables regulatory T cells to suppress excessive T2 responses in vivo
  - Ulges A, Klein M, Reuter S, Gerlitzki B, Hoffmann M, Grebe N, Staudt V, Stergiou N, Bohn T, Brühl TJ, Muth S, Yurugi H, Rajalingam K, Bellinghausen I, Tuettenberg A, Hahn S, Reißig S, Haben I, Zipp F, Waisman A, Probst HC, Beilhack A, Buchou T, Filhol-Cochet O, Boldyreff B, Breloer M, Jonuleit H, Schild H, Schmitt E, Bopp T
  - Nature immunology. 2015 Mar;16(3):267-75. doi: 10.1038/ni.3083
  - 2015-01-19
- Cutting Edge: The BTLA-HVEM Regulatory Pathway Interferes with Protective Immunity to Intestinal Helminth Infection
  - Breloer M, Hartmann W, Blankenhaus B, Eschbach ML, Pfeffer K, Jacobs T
  - Journal of Immunology. 2015 Feb 15;194(4):1413-6. doi: 10.4049/jimmunol.1402510
  - 2015-01-16
2014
- Nematode-Induced Interference with Vaccination Efficacy Targets Follicular T Helper Cell Induction and is Preserved after Termination of Infection
  - Haben I, Hartmann W, Breloer M
  - PLoS Negl Trop Dis. 2014 Sep 25;8(9):e3170. doi: 10.1371/journal.pntd.0003170
  - 2014-12-25
- Heat shock protein 60: an endogenous inducer of dopaminergic cell death in Parkinson disease
  - Noelker C, More L, Osterloh A, Alvarez-Fischer D, Lescot T, Breloer M, Gold M, Oertel W H, Henze C, Michel PP, Dodel RC, Lu L, Hirsch EC, Hunot E, Hartmann A
  - Journal of Neuroinflammation. 2014, 11:86 doi:10.1186/1742-2094-11-86
  - 2014-05-08
- Immune recognition of Onchocerca volvulus proteins in the human host and animal models of onchocerciasis
  - Manchang K, Ajonina-Ekoti I, Ndjonka D, Eisenbarth A, Achukwi M, Renz A, Brattig NW, Liebau E, Breloer M
  - J Helminthol. 2015 May;89(3):375-86. doi: 10.1017/S0022149X14000224
  - 2014-04-10
- Foxp3+ regulatory T cells delay expulsion of intestinal nematodes by suppression of IL-9-driven mast cell activation in BALB/c but not in C57BL/6 mice
  - Blankenhaus B, Reitz M, Brenz Y, Eschbach ML, Hartmann W, Haben I, Sparwasser T, Huehn J, Kühl A, Feyerabend TB, Rodewald HR, Breloer M
  - PLoS pathogens. 2014 Feb 6;10(2):e1003913. doi: 10.1371/journal.ppat.1003913
  - 2014-02-06
2013
- Immunization with Brugia malayi Hsp70 protects mice against Litomosoides sigmodontis challenge infection
  - Hartmann W, Singh N, Rathaur S, Brenz Y, Liebau E, Fleischer B, Breloer M
  - Parasite Immunol. 2014. 36: 141-149. doi: 10.1111/pim.12093
  - 2013-12-11
- Comparative analysis of macrophage migration inhibitory factors (MIFs) from the parasitic nematode Onchocerca volvulus and the free-living nematode Caenorhabditis elegans
  - Ajonina-Ekoti I, Kurosinski MA, Younis AE, Ndjonka D, Tanyi MK, Achukwi M, Eisenbarth A, Ajonina C, Lüersen K, Breloer M, Brattig, NW and Liebau E
  - Parasitology Research. 2013 Sep;112(9):3335-46. doi: 10.1007/s00436-013-3513-1
  - 2013-07-03
- T-cell-derived, but not B-cell-derived, IL-10 suppresses antigen-specific T-cell responses in Litomosoides sigmodontis-infected mice
  - Haben I, Hartmann W, Specht S, Hoerauf A, Roers A, Müller W, Breloer M
  - European Journal of Immunology. 2013 Jul;43(7):1799-805. doi: 10.1002/eji.201242929
  - 2013-07-01
- Nematode-derived proteins suppress proliferation and cytokine production of antigen-specific T Cells via induction of cell death
  - Hartmann W, Brenz Y, Kingsley MT, Ajonina-Ekoti I, Brattig NW, Liebau E, Breloer M
  - PLoS One. 2013 Jun 21;8(6):e68380. doi: 10.1371/journal.pone.0068380
  - 2013-06-21
- Toll like receptor 4 mediates cell death in a mouse MPTP model of Parkinson disease
  - Noelker C, Morel L, Lescot T, Osterloh A, Alvarez-Fischer D, Breloer M, Henze C, Depboylu C, Skrzydelski D, Michel PP, Dodel RC, Lu L, Hirsch EC, Hunot S, Hartmann A
  - Scientific Reports. 2013:3:1393. doi: 10.1038/srep01393
  - 2013-03-06
2012
- Functional characterization and immune recognition of the extracellular superoxide dismutase from the human pathogenic parasite Onchocerca volvulus (OvEC-SOD)
  - Ajonina-Ekoti I, Ndjonka D, Tanyi MK, Wilbertz M, Younis AE, Boursou D, Kurosinski MA, Eberle R, Lüersen K, Perbandt M, Breloer, M, Brattig NW, Liebau E
  - Acta Tropica. 2012 Oct;124(1):15-26. doi: 10.1016/j.actatropica.2012.05.013
  - 2012-10-01
- Efficient control of Plasmodium yoelii infection in BALB/c and C57BL/6 mice with pre-existing Strongyloides ratti infection
  - Kolbaum J, Eschbach ML, Steeg C, Jacobs T, Fleischer B, Breloer M
  - Parasite Immunology. 2012 Jul;34(7):388-93. doi: 10.1111/j.1365-3024.2012.01369.x
  - 2012-05-03
- Vaccination with Strongyloides ratti heat shock protein 60 increases susceptibility to challenge infection by induction of Th1 response
  - Nouir NB, Eschbach ML, Piédavent, M, Osterloh A, Kingsley MT, Erttmann K, Brattig N, Liebau E, Fleischer B, Breloer M
  - Vaccine. 2012 Jan 20;30(5):862-71. doi: 10.1016/j.vaccine.2011.11.110
  - 2012-01-22
2011
- Nematode-induced interference with the anti-Plasmodium CD8+ T-cell response can be overcome by optimizing antigen administration
  - Kolbaum J, Tartz S, Hartmann W, Helm S, Nagel A, Heussler V, Sebo P, Fleischer B, Jacobs T, Breloer M
  - European Journal of Immunology. 2012 Apr;42(4):890-900. doi: 10.1002/eji.201141955
  - 2011-12-12
- Pathogenic nematodes suppress humoral responses to third-party antigens in vivo by IL-10-mediated interference with Th cell function
  - Hartmann W, Haben I, Fleischer B, Breloer M
  - Journal of Immunology. 2011 Oct 15;187(8):4088-99. doi: 10.4049/jimmunol.1004136
  - 2011-10-15
- Strongyloides ratti infection modulates B and T cell responses to third party antigens
  - Hartmann W, Eschbach ML, Breloer M
  - Experimental Parasitology. 2012 Sep;132(1):69-75. doi: 10.1016/j.exppara.2011.06.001
  - 2011-06-23
- Activated T cells induce rapid CD83 expression on B cells by engagement of CD40
  - Kretschmer B, Kühl S, Fleischer B, Breloer M
  - Immunology Letters. 2011 May;136(2):221-7. doi: 10.1016/j.imlet.2011.01.013
  - 2011-05-01
- Strongyloides ratti infection induces expansion of Foxp3+ regulatory T cells that interfere with immune response and parasite clearance in BALB/c mice
  - Blankenhaus B, Klemm U, Eschbach ML, Sparwasser T, Huehn J, Kühl AA, Loddenkemper C, Jacobs T, Breloer M
  - Journal of Immunology. 2011 Apr 1;186(7):4295-305. doi: 10.4049/jimmunol.1001920
  - 2011-04-01
2010
- Efficient control of Leishmania and Strongyloides despite partial suppression of nematode-induced Th2 response in co-infected mice
  - Kolbaum J, Ritter U, Zimara N, Brewig N, Eschbach ML, Breloer M
  - Parasite Immunology. 2011 Apr;33(4):226-35. doi: 10.1111/j.1365-3024.2010.01273.x
  - 2010-11-09
- Strongyloides ratti infection induces transient nematode-specific Th2 response and reciprocal suppression of IFN-gamma production in mice
  - Eschbach ML, Klemm U, Kolbaum J, Blankenhaus B, Brattig N, Breloer M
  - Parasite Immunology. 2010 May;32(5):370-83. doi: 10.1111/j.1365-3024.2010.01199.x
  - 2010-04-08
2009
- Heat shock protein 60 (HSP60) stimulates neutrophil effector functions
  - Osterloh A, Geisinger F, Piédavent M, Fleischer B, Brattig N and Breloer M
  - Journal of Leukocyte Biology. 2009 Aug;86(2):423-34. doi: 10.1189/jlb.0109011
  - 2009-05-15
- Engagement of CD83 on B cells modulates B cell function in vivo
  - Kretschmer B, Lüthje K, Schneider S, Fleischer B, Breloer M
  - Journal of Immunology. 2009 Mar 1;182(5):2827-34. doi: 10.4049/jimmunol.0803153
  - 2009-03-01
2008
- CD83 on murine APC does not function as a costimulatory receptor for T cells
  - Kretschmer B, Lüthje K, Ehrlich S, Osterloh A, Piédavent M, Fleischer B, Breloer M
  - Immunology Letters. 2008 Oct 30;120(1-2):87-95. doi: 10.1016/j.imlet.2008.07.004
  - 2008-09-30
- CD83 regulates splenic B cell maturation and peripheral B cell homeostasis
  - Lüthje K, Kretschmer B, Fleischer B, Breloer M
  - International Immunology. 2008 Aug;20(8):949-60. doi: 10.1093/intimm/dxn054
  - 2008-06-10
- CD83 expression in CD4+ T cells modulates inflammation and autoimmunity
  - Reinwald S, Wiethe C, Westendorf AM, Breloer M, Probst-Kepper M, Fleischer B, Steinkasserer A, Buer J, Hansen W
  - Journal of Immunology. 2008 May 1;180(9):5890-7. doi: 10.4049/jimmunol.180.9.5890
  - 2008-05-01
- CD83 regulates lymphocyte maturation, activation and homeostasis
  - Breloer M, Fleischer B
  - Trends in Immunology. 2008 Apr;29(4):186-94. doi: 10.1016/j.it.2008.01.009
  - 2008-04-01
- Heat shock proteins: linking danger and pathogen recognition
  - Osterloh A, Breloer M
  - Medical Microbiology and Immunology. 2008 Mar;197(1):1-8. doi: 10.1007/s00430-007-0055-0
  - 2008-03-01
- Hsp60-mediated T cell stimulation is independent of TLR4 and IL-12
  - Osterloh A, Veit A, Gessner A, Fleischer B, Breloer M
  - International Immunology. 2008 Mar;20(3):433-43. doi: 10.1093/intimm/dxn003
  - 2008-02-05
- CD83: regulator of central T cell maturation and peripheral immune response
  - Breloer M
  - Immunology Letters. 2008 Jan 15;115(1):16-7. doi: 10.1016/j.imlet.2007.10.007
  - 2008-01-15
2007
- CD83 modulates B cell function in vitro: increased IL-10 and reduced Ig secretion by CD83Tg B cells
  - Kretschmer B, Lüthje K, Guse AH, Ehrlich S, Koch-Nolte F, Haag F, Fleischer B, Breloer M
  - PLoS One. 2007 Aug 15;2(8):e755. doi: 10.1371/journal.pone.0000755
  - 2007-08-15
- CD83 is a regulator of murine B cell function in vivo
  - Breloer M, Kretschmer B, Lüthje K, Ehrlich S, Ritter U, Bickert T, Steeg C, Fillatreau S, Hoehlig K, Lampropoulou V, Fleischer B
  - European Journal of Immunology. 2007 Mar;37(3):634-48. doi: 10.1002/eji.200636852
  - 2007-02-23
- Synergistic and differential modulation of immune responses by Hsp60 and lipopolysaccharide
  - Osterloh A, Kalinke U, Weiss S, Fleischer B, Breloer M
  - The Journal of Biological Chemistry. 2007 Feb 16;282(7):4669-4680. doi: 10.1074/jbc.M608666200
  - 2007-02-16
2006
- Transgenic expression of a CD83-immunoglobulin fusion protein impairs the development of immune-competent CD4-positive T cells
  - Lüthje K, Cramer SO, Ehrlich S, Veit A, Steeg C, Fleischer B, Bonin Av and Breloer M
  - European Journal of Immunology. 2006 Aug;36(8):2035-45. doi: 10.1002/eji.200636068
  - 2006-07-27
2005
- Heat shock protein 60 is released in immune-mediated glomerulonephritis and aggravates disease: in vivo evidence for an immunologic danger signal
  - Lang A, Benke D, Eitner F, Engel D, Ehrlich S, Breloer M, Hamilton-Williams E, Specht S, Hoerauf A, Floege J, von Bonin A, Kurts C
  - Journal of the American Society of Nephrology. 2005 Feb;16(2):383-91. doi: 10.1681/ASN.2004040276
  - 2005-02-01
2004
- Lipopolysaccharide-free heat shock protein 60 activates T cells
  - Osterloh A, Meier-Stiegen F, Veit A, Fleischer B, von Bonin A and Breloer M
  - The Journal of Biological Chemistry. 2004 Nov 12;279(46):47906-11. doi: 10.1074/jbc.M408440200
  - 2004-11-01
2003
- Purification of the eucaryotic heat-shock proteins Hsp70 and gp96
  - von Bonin A, Moré SH, Breloer M
  - Methods in Molecular Biology. 2003:215:193-200. doi: 10.1385/1-59259-345-3:193
  - 2003-01-01
2002
- Macrophages as main inducers of IFN-gamma in T cells following administration of human and mouse heat shock protein 60
  - Breloer M, Moré SH, Osterloh A, Stelter F, Jack RS, Bonin Av
  - International Immunology. 2002 Nov;14(11):1247-53. doi: 10.1093/intimm/dxf090
  - 2002-11-01
- 'Ignorance' of antigen-specific murine CD4+ and CD8+ T cells is overruled by lipopolysaccharide and leads to specific induction of IFN-gamma
  - Moré SH, Breloer M, Fentz AK, Fleischer B, von Bonin A
  - Scandinavian Journal of Immunology 2002 Apr;55(4):329-35. doi: 10.1046/j.1365-3083.2002.01061.x
  - 2002-04-25
2001
- Eukaryotic heat shock proteins as molecular links in innate and adaptive immune responses: Hsp60-mediated activation of cytotoxic T cells
  - Moré SH, Breloer M, von Bonin A
  - International Immunology. 2001 Sep;13(9):1121-7. doi: 10.1093/intimm/13.9.1121
  - 2001-09-01
- Heat shock proteins as "danger signals": eukaryotic Hsp60 enhances and accelerates antigen-specific IFN-gamma production in T cells
  - Breloer M, Dorner B, Moré SH, Roderian T, Fleischer B, von Bonin A
  - European Journal of Immunology. 2001 Jul;31(7):2051-9. doi: 10.1002/1521-4141(200107)31:7<2051::aid-immu2051>3.0.co;2-h
  - 2001-06-27
1999
- Activation of cytotoxic T cells in vitro by recombinant gp96 fusion proteins irrespective of the 'fused' antigenic peptide sequence
  - Moré S, Breloer M, Fleischer B, von Bonin A
  - Immunology Letters. 1999 Aug 3;69(2):275-82. doi: 10.1016/s0165-2478(99)00100-5.
  - 1999-08-03
- In vivo and in vitro activation of T cells after administration of Ag-negative heat shock proteins
  - Breloer M, Fleischer B, von Bonin A
  - Journal of Immunology. 1999 Mar 15;162(6):3141-7
  - 1999-03-15
1998
- Partial agonism and independent modulation of T cell receptor and CD8 in hapten-specific cytotoxic T cells
  - Preckel T, Breloer M, Kohler H, von Bonin A, Weltzien HU
  - European Journal of Immunology. 1998 Nov;28(11):3706-18. doi: 10.1002/(SICI)1521-4141(199811)28:11<3706::AID-IMMU3706>3.0.CO;2-7
  - 1998-12-14
- Amino acid sequence of the D-galactose binding lectin II from the sponge Axinella polypoides (Schmidt) and identification of the carbohydrate binding site in lectin II and related lectin I
  - Buck F, Schulze C, Breloer M, Strupat K, Bretting H
  - Comparative Biochemistry and Physiology. 1998 Oct;121(2):153-60. doi: 10.1016/s0305-0491(98)10083-
  - 1998-10-01
- Isolation of processed, H-2Kb-binding ovalbumin-derived peptides associated with the stress proteins HSP70 and gp96
  - Breloer M, Marti T, Fleischer B, von Bonin A
  - European Journal of Immunology. 1998 Mar;28(3):1016-21. doi: 10.1002/(SICI)1521-4141(199803)28:03<1016::AID-IMMU1016>3.0.CO;2-G
  - 1998-01-16
1996
- A biological function for the XP motif within the N terminus of major histocompatibility complex class II-associated peptides
  - Breloer M, Ehrlich S, Fleischer B, von Bonin A
  - European Journal of Immunology. 1996 Aug;26(8):1825-9. doi: 10.1002/eji.1830260824
  - 1996-08-01