• Mosquito trapping site "Weinheim" in southwest Germany. Origin of the first German Usutu virus and Sindbis virus isolates.

Overview

Interessenkonflikte Corona-Pressearbeit

Die Pressearbeit ist Ergebnis des Bemühens um größtmögliche Objektivität und Unabhängigkeit. Ich versichere, dass in Bezug auf den Inhalt der Pressearbeit bezüglich der Coronavirus-Pandemie (SARS-CoV-2 und der damit zusammenhängen Krankheit COVID-19) folgende Interessenkonflikte bestehen können, die sich aus einem Beschäftigungsverhältnis, einer Teilhabe, einer Beratertätigkeit oder Zuwendungen für Forschungsvorhaben, Vorträge oder andere Tätigkeiten ergeben oder in den letzten fünf Jahren ergeben haben:

Prof. Jonas Schmidt-Chanasit

  • Euroimmun - Perkin Elmer
  • BASF
  • Siemens
  • Roche
  • Sonic Healthcare
  • Wynn Macau
  • Bangkok Bank
  • China Construction Bank
  • Deutsche Bank
  • Diasorin
  • Sanofi
  • Mikrogen
  • Blusense Diagnostics
  • Mahidol University
  • Vietnam Military Medical University
  • Generali
  • Pfizer
  • DFG
  • BMBF
  • BMG
  • BMEL
  • INSTAND e.V.
  • Auswärtiges Amt
  • QCMD

We investigate how arboviruses interact with their mosquito vectors and how these interactions affect virus evolution and transmissibility. We are studying the biotic and abiotic factors of arbovirus emergence and are involved in arbovirus outbreak response. In addition, we provide specific support for outbreak response to the WHO Collaborating Centre for Arbovirus and Haemorrhagic Fever Reference and Research including on-the-spot investigations, confirmation of diagnosis, handling of dangerous (biosafety level III) pathogens, case detection, and provision of logistics in the form of staff and supplies.

Currently, there are 4 study groups within the department that are performing arbovirus research worldwide.

Research Projects

Publication Highlights

Arbeitsgruppe Schmidt-Chanasit (Arbovirologie)

Fatal Encephalitic Borna Disease Virus 1 in Solid-Organ Transplant Recipients.
Schlottau K, Forth L, Angstwurm K, Höper D, Zecher D, Liesche F, Hoffmann B, Kegel V, Seehofer D, Platen S, Salzberger B, Liebert UG, Niller HH, Schmidt B, Matiasek K, Riemenschneider MJ, Brochhausen C, Banas B, Renders L, Moog P, Wunderlich S, Seifert CL, Barreiros A, Rahmel A, Weiss J, Tappe D, Herden C, Schmidt-Chanasit J, Schwemmle M, Rubbenstroth D, Schlegel J, Pietsch C, Hoffmann D, Jantsch J, Beer M.
N Engl J Med. 2018 Oct 4;379(14):1377-1379. doi: 10.1056/NEJMc1803115.

Autochthonous Crimean–Congo Hemorrhagic Fever in Spain
Negredo A, de la Calle-Prieto F, Palencia-Herrejón E, Mora-Rillo M, Astray-Mochales J, Sánchez-Seco MP, Bermejo Lopez E, Menárguez J, Fernández-Cruz A, Sánchez-Artola B, Keough-Delgado E, Ramírez de Arellano E, Lasala F, Milla J, Fraile JL, Ordobás Gavín M, Martinez de la Gándara A, López Perez L, Diaz-Diaz D, López-García MA, Delgado-Jimenez P, Martín-Quirós A, Trigo E, Figueira JC, Manzanares J, Rodriguez-Baena E, Garcia-Comas L, Rodríguez-Fraga O, García-Arenzana N, Fernández-Díaz MV, Cornejo VM, Emmerich P, Schmidt-Chanasit J, Arribas JR
N Engl J Med. 2017 Jul 13;377(2):154-161. doi: 10.1056/NEJMoa1615162.

Phase 1 Trials of rVSV Ebola Vaccine in Africa and Europe.
Agnandji ST, Huttner A, Zinser ME, Njuguna P, Dahlke C, Fernandes JF, Yerly S, Dayer JA, Kraehling V, Kasonta R, Adegnika AA, Altfeld M, Auderset F, Bache EB, Biedenkopf N, Borregaard S, Brosnahan JS, Burrow R, Combescure C, Desmeules J, Eickmann M, Fehling SK, Finckh A, Goncalves AR, Grobusch MP, Hooper J, Jambrecina A, Kabwende AL, Kaya G, Kimani D, Lell B, Lemaître B, Lohse AW, Massinga-Loembe M, Matthey A, Mordmüller B, Nolting A, Ogwang C, Ramharter M, Schmidt-Chanasit J, Schmiedel S, Silvera P, Stahl FR, Staines HM, Strecker T, Stubbe HC, Tsofa B, Zaki S, Fast P, Moorthy V, Kaiser L, Krishna S, Becker S, Kieny MP, Bejon P, Kremsner PG, Addo MM, Siegrist CA.
N Engl J Med. 2016 Apr 28;374(17):1647-60. doi: 10.1056/NEJMoa1502924.

Bornavirus Associated with Fatal Human Encephalitis.
Tappe D, Schmidt-Chanasit J, Beer M.
N Engl J Med. 2015 Nov 5;373(19):1880-1. doi: 10.1056/NEJMc1510342.

A Variegated Squirrel Bornavirus Associated with Fatal Human Encephalitis.
Hoffmann B, Tappe D, Höper D, Herden C, Boldt A, Mawrin C, Niederstraßer O, Müller T, Jenckel M, van der Grinten E, Lutter C, Abendroth B, Teifke JP, Cadar D, Schmidt-Chanasit J, Ulrich RG, Beer M.
N Engl J Med. 2015 Jul 9;373(2):154-62. doi: 10.1056/NEJMoa1415627.

A case of severe Ebola virus infection complicated by gram-negative septicemia.
Kreuels B, Wichmann D, Emmerich P, Schmidt-Chanasit J, de Heer G, Kluge S, Sow A, Renné T, Günther S, Lohse AW, Addo MM, Schmiedel S.
N Engl J Med. 2014 Dec 18;371(25):2394-401. doi: 10.1056/NEJMoa1411677.

Emergence of Zaire Ebola virus disease in Guinea.
Baize S, Pannetier D, Oestereich L, Rieger T, Koivogui L, Magassouba N, Soropogui B, Sow MS, Keïta S, De Clerck H, Tiffany A, Dominguez G, Loua M, Traoré A, Kolié M, Malano ER, Heleze E, Bocquin A, Mély S, Raoul H, Caro V, Cadar D, Gabriel M, Pahlmann M, Tappe D, Schmidt-Chanasit J, Impouma B, Diallo AK, Formenty P, Van Herp M, Günther S.
N Engl J Med. 2014 Oct 9;371(15):1418-25. doi: 10.1056/NEJMoa1404505.

All Publications

2019 (selected)

Serum cytokine and chemokine changes during Toscana virus meningitis.
Rauch J, Zammarchi L, Corti G, Bartoloni A, Schlaphof A, Schmidt-Chanasit J, Tappe D.
Med Microbiol Immunol. 2019 Dec;208(6):727-730. doi: 10.1007/s00430-019-00611-y.

Detection of novel tick-borne pathogen, Alongshan virus, in Ixodes ricinus ticks, south-eastern Finland, 2019.
Kuivanen S, Levanov L, Kareinen L, Sironen T, Jääskeläinen AJ, Plyusnin I, Zakham F, Emmerich P, Schmidt-Chanasit J, Hepojoki J, Smura T, Vapalahti O.
Euro Surveill. 2019 Jul;24(27). doi: 10.2807/1560-7917.ES.2019.24.27.1900394.

Immunoassay for serodiagnosis of Zika virus infection based on time-resolved Förster resonance energy transfer.
Kareinen L, Hepojoki S, Huhtamo E, Korhonen EM, Schmidt-Chanasit J, Hedman K, Hepojoki J, Vapalahti O.
PLoS One. 2019 Jul 23;14(7):e0219474. doi: 10.1371/journal.pone.0219474.

A novel group of avian astroviruses from Neotropical passerine birds broaden the diversity and host range of Astroviridae.
Fernández-Correa I, Truchado DA, Gomez-Lucia E, Doménech A, Pérez-Tris J, Schmidt-Chanasit J, Cadar D, Benítez L.
Sci Rep. 2019 Jul 2;9(1):9513. doi: 10.1038/s41598-019-45889-3.

Culex torrentium: A Potent Vector for the Transmission of West Nile Virus in Central Europe.
Jansen S, Heitmann A, Lühken R, Leggewie M, Helms M, Badusche M, Rossini G, Schmidt-Chanasit J, Tannich E.
Viruses. 2019 May 29;11(6). pii: E492. doi: 10.3390/v11060492.

Immunopathology of Fatal Human Variegated Squirrel Bornavirus 1 Encephalitis, Germany, 2011-2013.
Tappe D, Schmidt-Chanasit J, Rauch J, Allartz P, Herden C.
Emerg Infect Dis. 2019 Jun;25(6):1058-1065. doi: 10.3201/eid2506.181082.

Diagnosing Zika virus infection against a background of other flaviviruses: Studies in high resolution serological analysis.
Hansen S, Hotop SK, Faye O, Ndiaye O, Böhlken-Fascher S, Pessôa R, Hufert F, Stahl-Hennig C, Frank R, Czerny CP, Schmidt-Chanasit J, Sanabani SS, Sall AA, Niedrig M, Brönstrup M, Fritz HJ, Abd El Wahed A.
Sci Rep. 2019 Mar 6;9(1):3648. doi: 10.1038/s41598-019-40224-2.

Immunoglobulin-like Domain of HsFcμR as a Capture Molecule for Detection of Crimean-Congo Hemorrhagic Fever Virus- and Zika Virus-Specific IgM Antibodies.
Rackow A, Ehmen C, von Possel R, Medialdea-Carrera R, Brown D, Bispo de Filippis AM, Carvalho de Sequeira P, Ribeiro Nogueira RM, Halili B, Jakupi X, Berisha L, Ahmeti S, Sherifi K, Schmidt-Chanasit J, Schmitz H, Mika A, Emmerich P, Deschermeier C.
Clin Chem. 2019 Mar;65(3):451-461. doi: 10.1373/clinchem.2018.294819.

West Nile virus epizootic in Germany, 2018.
Ziegler U, Lühken R, Keller M, Cadar D, van der Grinten E, Michel F, Albrecht K, Eiden M, Rinder M, Lachmann L, Höper D, Vina-Rodriguez A, Gaede W, Pohl A, Schmidt-Chanasit J, Groschup MH.
Antiviral Res. 2019 Feb;162:39-43. doi: 10.1016/j.antiviral.2018.12.005.

Analysis of exotic squirrel trade and detection of human infections with variegated squirrel bornavirus 1, Germany, 2005 to 2018.
Tappe D, Frank C, Homeier-Bachmann T, Wilking H, Allendorf V, Schlottau K, Muñoz-Fontela C, Rottstegge M, Port JR, Rissland J, Eisermann P, Beer M, Schmidt-Chanasit J.
Euro Surveill. 2019 Feb;24(8). doi: 10.2807/1560-7917.ES.2019.24.8.1800483.

Dengue Virus IgM Serotyping by ELISA with Recombinant Mutant Envelope Proteins.
Rockstroh A, Barzon L, Kumbukgolla W, Su HX, Lizarazo E, Vincenti-Gonzalez MF, Tami A, Ornelas AMM, Aguiar RS, Cadar D, Schmidt-Chanasit J, Ulbert S.
Emerg Infect Dis. 2019 Jan;25(1):1111-1115. doi: 10.3201/eid2501.180605.

Inhibition by Marine Algae of Chikungunya Virus Isolated From Patients in a Recent Disease Outbreak in Rio de Janeiro.
Cirne-Santos CC, Barros CS, Nogueira CCR, Azevedo RC, Yamamoto KA, Meira GLS, de Vasconcelos ZFM, Ratcliffe NA, Teixeira VL, Schmidt-Chanasit J, Ferreira DF, Paixão ICNP.
Front Microbiol. 2019 Oct 24;10:2426. doi: 10.3389/fmicb.2019.02426.

Comparative analysis of subsampling methods for large mosquito samples.
Jaworski L, Jansen S, Pfitzner WP, Beck M, Becker N, Schmidt-Chanasit J, Kiel E, Lühken R.
Parasit Vectors. 2019 Jul 16;12(1):354. doi: 10.1186/s13071-019-3606-5.

2018 (selected)

Experimental risk assessment for chikungunya virus transmission based on vector competence, distribution and temperature suitability in Europe, 2018.
Heitmann A, Jansen S, Lühken R, Helms M, Pluskota B, Becker N, Kuhn C, Schmidt-Chanasit J, Tannich E.
Euro Surveill. 2018 Jul;23(29). doi: 10.2807/1560-7917.ES.2018.23.29.1800033.

Host-feeding patterns of Culex mosquitoes in Iran.
Shahhosseini N, Friedrich J, Moosa-Kazemi SH, Sedaghat MM, Kayedi MH, Tannich E, Schmidt-Chanasit J, Lühken R.
Parasit Vectors. 2018 Dec 27;11(1):669. doi: 10.1186/s13071-018-3237-2.

Male offspring born to mildly ZIKV-infected mice are at risk of developing neurocognitive disorders in adulthood.
Stanelle-Bertram S, Walendy-Gnirß K, Speiseder T, Thiele S, Asante IA, Dreier C, Kouassi NM, Preuß A, Pilnitz-Stolze G, Müller U, Thanisch S, Richter M, Scharrenberg R, Kraus V, Dörk R, Schau L, Herder V, Gerhauser I, Pfankuche VM, Käufer C, Waltl I, Moraes T, Sellau J, Hoenow S, Schmidt-Chanasit J, Jansen S, Schattling B, Ittrich H, Bartsch U, Renné T, Bartenschlager R, Arck P, Cadar D, Friese MA, Vapalahti O, Lotter H, Benites S, Rolling L, Gabriel M, Baumgärtner W, Morellini F, Hölter SM, Amarie O, Fuchs H, Hrabe de Angelis M, Löscher W, Calderon de Anda F, Gabriel G.
Nat Microbiol. 2018 Oct;3(10):1161-1174. doi: 10.1038/s41564-018-0236-1.

Forced Salivation As a Method to Analyze Vector Competence of Mosquitoes.
Heitmann A, Jansen S, Lühken R, Leggewie M, Schmidt-Chanasit J, Tannich E.
J Vis Exp. 2018 Aug 7;(138). doi: 10.3791/57980.

Experimental transmission of Zika virus by Aedes japonicus japonicus from southwestern Germany.
Jansen S, Heitmann A, Lühken R, Jöst H, Helms M, Vapalahti O, Schmidt-Chanasit J, Tannich E
Emerg Microbes Infect. 2018 Nov 28;7(1):192. doi: 10.1038/s41426-018-0195-x.

Viral metagenomics, genetic and evolutionary characteristics of Crimean-Congo hemorrhagic fever orthonairovirus in humans, Kosovo.
Emmerich P, Jakupi X, von Possel R, Berisha L, Halili B, Günther S, Cadar D, Ahmeti S, Schmidt-Chanasit J.
Infect Genet Evol. 2018 Jul 11;65:6-11. doi: 10.1016/j.meegid.2018.07.010.

Yellow fever in the diagnostic laboratory.
Domingo C, Charrel RN, Schmidt-Chanasit J, Zeller H, Reusken C.
Emerg Microbes Infect. 2018 Jul 12;7(1):129. doi: 10.1038/s41426-018-0128-8.

Circulation of Dirofilaria immitis and Dirofilaria repens in the Danube Delta Biosphere Reserve, Romania.
Tomazatos A, Cadar D, Török E, Maranda I, Horváth C, Keresztes L, Spinu M, Jansen S, Jöst H, Schmidt-Chanasit J, Tannich E, Lühken R.
Parasit Vectors. 2018 Jul 4;11(1):392. doi: 10.1186/s13071-018-2980-8.

Semen inhibits Zika virus infection of cells and tissues from the anogenital region.
Müller JA, Harms M, Krüger F, Groß R, Joas S, Hayn M, Dietz AN, Lippold S, von Einem J, Schubert A, Michel M, Mayer B, Cortese M, Jang KS, Sandi-Monroy N, Deniz M, Ebner F, Vapalahti O, Otto M, Bartenschlager R, Herbeuval JP, Schmidt-Chanasit J, Roan NR, Münch J.
Nat Commun. 2018 Jun 7;9(1):2207. doi: 10.1038/s41467-018-04442-y.

Occupation-Associated Fatal Limbic Encephalitis Caused by Variegated Squirrel Bornavirus 1, Germany, 2013.
Tappe D, Schlottau K, Cadar D, Hoffmann B, Balke L, Bewig B, Hoffmann D, Eisermann P, Fickenscher H, Krumbholz A, Laufs H, Huhndorf M, Rosenthal M, Schulz-Schaeffer W, Ismer G, Hotop SK, Brönstrup M, Ott A, Schmidt-Chanasit J, Beer M.
Emerg Infect Dis. 2018 Jun;24(6):978-987. doi: 10.3201/eid2406.172027.

The molecular tweezer CLR01 inhibits Ebola and Zika virus infection.
Röcker AE, Müller JA, Dietzel E, Harms M, Krüger F, Heid C, Sowislok A, Riber CF, Kupke A, Lippold S, von Einem J, Beer J, Knöll B, Becker S, Schmidt-Chanasit J, Otto M, Vapalahti O, Zelikin AN, Bitan G, Schrader T, Münch J.
Antiviral Res. 2018 Apr;152:26-35. doi: 10.1016/j.antiviral.2018.02.003.

Culex torrentium mosquitoes from Germany are negative for Wolbachia.
Leggewie M, Krumkamp R, Badusche M, Heitmann A, Jansen S, Schmidt-Chanasit J, Tannich E, Becker SC.
Med Vet Entomol. 2018 Mar;32(1):115-120. doi: 10.1111/mve.12270.

Vector competence of field populations of the mosquito species Aedes japonicus japonicus and Culex pipiens from Switzerland for two West Nile virus strains.
Wagner S, Mathis A, Schönenberger AC, Becker S, Schmidt-Chanasit J, Silaghi C, Veronesi E.
Med Vet Entomol. 2018 Mar;32(1):121-124. doi: 10.1111/mve.12273.

2017 (selected)

Distribution of Usutu Virus in Germany and Its Effect on Breeding Bird Populations.
Lühken R, Jöst H, Cadar D, Thomas SM, Bosch S, Tannich E, Becker N, Ziegler U, Lachmann L, Schmidt-Chanasit J.
Emerg Infect Dis. 2017 Dec;23(12):1994-2001. doi: 10.3201/eid2312.171257

Specific detection of dengue and Zika virus antibodies using envelope proteins with mutations in the conserved fusion loop.
Rockstroh A, Moges B, Barzon L, Sinigaglia A, Palù G, Kumbukgolla W, Schmidt-Chanasit J, Sarno M, Brites C, Moreira-Soto A, Drexler JF, Ferreira OC, Ulbert S.
Emerg Microbes Infect. 2017 Nov 8;6(11):e99. doi: 10.1038/emi.2017.87

Detection and characterization of a novel rhabdovirus in Aedes cantans mosquitoes and evidence for a mosquito-associated new genus in the family Rhabdoviridae.
Shahhosseini N, Lühken R, Jöst H, Jansen S, Börstler J, Rieger T, Krüger A, Yadouleton A, de Mendonça Campos R, Cirne-Santos CC, Ferreira DF, Garms R, Becker N, Tannich E, Cadar D, Schmidt-Chanasit J.
Infect Genet Evol. 2017 Sep 21;55:260-268. doi: 10.1016/j.meegid.2017.09.026.

Compensating for cross-reactions using avidity and computation in a suspension multiplex immunoassay for serotyping of Zika versus other flavivirus infections.
Rönnberg B, Gustafsson Å, Vapalahti O, Emmerich P, Lundkvist Å, Schmidt-Chanasit J, Blomberg J.
Med Microbiol Immunol. 2017 Aug 29. doi: 10.1007/s00430-017-0517-y.

West Nile Virus lineage-2 in Culex specimens from Iran.
Shahhosseini N, Chinikar S, Moosa-Kazemi SH, Sedaghat MM, Kayedi MH, Lühken R, Schmidt-Chanasit J.
Trop Med Int Health. 2017 Jul 26. doi: 10.1111/tmi.12935.

Early Evidence for Zika Virus Circulation among Aedes aegypti Mosquitoes, Rio de Janeiro, Brazil.
Ayllón T, Campos RM, Brasil P, Morone FC, Câmara DCP, Meira GLS, Tannich E, Yamamoto KA, Carvalho MS, Pedro RS, Schmidt-Chanasit J, Cadar D, Ferreira DF, Honório NA.
Emerg Infect Dis. 2017 Aug 15;23(8). doi: 10.3201/eid2308.162007.

Blood donor screening for West Nile virus (WNV) revealed acute Usutu virus (USUV) infection, Germany, September 2016.
Cadar D, Maier P, Müller S, Kress J, Chudy M, Bialonski A, Schlaphof A, Jansen S, Jöst H, Tannich E, Runkel S, Hitzler WE, Hutschenreuter G, Wessiepe M, Schmidt-Chanasit J.
Euro Surveill. 2017;22(14):pii=30501. DOI: http://dx.doi.org/10.2807/1560-7917.

No serological evidence for Zika virus infection and low specificity for anti-Zika virus ELISA in malaria positive individuals among pregnant women from Madagascar in 2010.
Schwarz NG, Mertens E, Winter D, Maiga-Ascofaré O, Dekker D, Jansen S, Tappe D, Randriamampionona N, May J, Rakotozandrindrainy R, Schmidt-Chanasit J.
PLoS One. 2017 May 16;12(5):e0176708. doi: 10.1371/journal.pone.0176708.

Increased Proinflammatory Cytokine Levels in Prolonged Arthralgia in Ross River Virus Infection.
Tappe D, Pérez-Girón JV, Gómez-Medina S, Günther S, Muñoz-Fontela C, Schmidt-Chanasit J.
Emerg Infect Dis. 2017 Apr;23(4):702-704. doi: 10.3201/eid2304.160466.

Widespread activity of multiple lineages of Usutu virus, western Europe, 2016.
Cadar D, Lühken R, van der Jeugd H, Garigliany M, Ziegler U, Keller M, Lahoreau J, Lachmann L, Becker N, Kik M, Oude Munnink BB, Bosch S, Tannich E, Linden A, Schmidt V, Koopmans MP, Rijks J, Desmecht D, Groschup MH, Reusken C, Schmidt-Chanasit J.
Euro Surveill. 2017 Jan 26;22(4). pii: 30452. doi: 10.2807/1560-7917.ES.2017.22.4.30452.

Genetic Diversity and New Lineages of Dengue Virus Serotypes 3 and 4 in Returning Travelers, Germany, 2006-2015.
Shihada S, Emmerich P, Thomé-Bolduan C, Jansen S, Günther S, Frank C, Schmidt-Chanasit J, Cadar D.
Emerg Infect Dis. 2017 Feb;23(2):272-275. doi: 10.3201/eid2302.160751.

Recent Zika Virus Isolates Induce Premature Differentiation of Neural Progenitors in Human Brain Organoids.
Gabriel E, Ramani A, Karow U, Gottardo M, Natarajan K, Gooi LM, Goranci-Buzhala G, Krut O, Peters F, Nikolic M, Kuivanen S, Korhonen E, Smura T, Vapalahti O, Papantonis A, Schmidt-Chanasit J, Riparbelli M, Callaini G, Krönke M, Utermöhlen O, Gopalakrishnan J.
Cell Stem Cell. 2017 Jan 23. pii: S1934-5909(16)30461-1. doi: 10.1016/j.stem.2016.12.005.

Experimental transmission of Zika virus by mosquitoes from central Europe.
Heitmann A, Jansen S, Lühken R, Leggewie M, Badusche M, Pluskota B, Becker N, Vapalahti O, Schmidt-Chanasit J, Tannich E.
Euro Surveill. 2017 Jan 12;22(2). pii: 30437. doi: 10.2807/1560-7917.ES.2017.22.2.30437.

Development of a high-throughput colorimetric Zika virus infection assay.
Müller JA, Harms M, Schubert A, Mayer B, Jansen S, Herbeuval JP, Michel D, Mertens T, Vapalahti O, Schmidt-Chanasit J, Münch J.
Med Microbiol Immunol. 2017 Feb 7. doi: 10.1007/s00430-017-0493-2.

Yellow fever in a traveller returning from Suriname to the Netherlands, March 2017.
Wouthuyzen-Bakker M, Knoester M, van den Berg AP, GeurtsvanKessel CH, Koopmans MP, Van Leer-Buter C, Oude Velthuis B, Pas SD, Ruijs WL, Schmidt-Chanasit J, Vreden SG, van der Werf TS, Reusken CB, Bierman WF.
Euro Surveill. 2017;22(11):pii=30488. DOI: http://dx.doi.org/10.2807/1560-7917.ES.2017.22.11.30488

Variegated Squirrel Bornavirus 1 in Squirrels, Germany and the Netherlands.
Schlottau K, Jenckel M, van den Brand J, Fast C, Herden C, Höper D, Homeier-Bachmann T, Thielebein J, Mensing N, Diender B, Hoffmann D, Ulrich RG, Mettenleiter TC, Koopmans M, Tappe D, Schmidt-Chanasit J, Reusken CB, Beer M, Hoffmann B.
Emerg Infect Dis. 2017 Mar;23(3):477-481. doi: 10.3201/eid2303.161061.

2016 (selected)

Serodiagnosis of Zika virus (ZIKV) infections by a novel NS1-based ELISA devoid of cross-reactivity with dengue virus antibodies: a multicohort study of assay performance, 2015 to 2016.
Steinhagen K, Probst C, Radzimski C, Schmidt-Chanasit J, Emmerich P, van Esbroeck M, Schinkel J, Grobusch MP, Goorhuis A, Warnecke JM, Lattwein E, Komorowski L, Deerberg A, Saschenbrecker S, Stöcker W, Schlumberger W.
Euro Surveill. 2016 Dec 15;21(50). pii: 30426. doi: 10.2807/1560-7917.ES.2016.21.50.30426.

High specificity of a novel Zika virus ELISA in European patients after exposure to different flaviviruses.
Huzly D, Hanselmann I, Schmidt-Chanasit J, Panning M.
Euro Surveill. 2016 Apr 21;21(16). doi: 10.2807/1560-7917.ES.2016.21.16.30203.

Assay optimization for molecular detection of Zika virus.
Corman VM, Rasche A, Baronti C, Aldabbagh S, Cadar D, Reusken CB, Pas SD, Goorhuis A, Schinkel J, Molenkamp R, Kümmerer BM, Bleicker T, Brünink S, Eschbach-Bludau M, Eis-Hübinger AM, Koopmans MP, Schmidt-Chanasit J, Grobusch MP, de Lamballerie X, Drosten C, Drexler JF.
Bull World Health Organ. 2016 Dec 1;94(12):880-892.

Inactivation and Environmental Stability of Zika Virus.
Müller JA, Harms M, Schubert A, Jansen S, Michel D, Mertens T, Schmidt-Chanasit J, Münch J.
Emerg Infect Dis. 2016 Sep 15;22(9). doi: 10.3201/eid2209.160664

Sexual transmission of Zika virus in Germany, April 2016.
Frank C, Cadar D, Schlaphof A, Neddersen N, Günther S, Schmidt-Chanasit J, Tappe D.
Euro Surveill. 2016 Jun 9;21(23). doi: 10.2807/1560-7917.ES.2016.21.23.30252.

Cytokine kinetics of Zika virus-infected patients from acute to reconvalescent phase.
Tappe D, Pérez-Girón JV, Zammarchi L, Rissland J, Ferreira DF, Jaenisch T, Gómez-Medina S, Günther S, Bartoloni A, Muñoz-Fontela C, Schmidt-Chanasit J.
Med Microbiol Immunol. 2016 10.1007/s00430-015-0445-7

Confirmed Zika virus infection in a Belgian traveler returning from Guatemala, and the diagnostic challenges of imported cases into Europe.
De Smet B, Van den Bossche D, van de Werve C, Mairesse J, Schmidt-Chanasit J, Michiels J, Ariën KK, Van Esbroeck M, Cnops L.
J Clin Virol. 2016 Jul;80:8-11. doi: 10.1016/j.jcv.2016.04.009

Prolonged detection of Zika virus RNA in urine samples during the ongoing Zika virus epidemic in Brazil.
de M Campos R, Cirne-Santos C, Meira GL, Santos LL, de Meneses MD, Friedrich J, Jansen S, Ribeiro MS, da Cruz IC, Schmidt-Chanasit J, Ferreira DF.
J Clin Virol. 2016 Feb 16;77:69-70. doi: 10.1016/j.jcv.2016.02.009.

Zika without symptoms in returning travellers: What are the implications?
Ginier M, Neumayr A, Günther S, Schmidt-Chanasit J, Blum J.
Travel Med Infect Dis. 2016 Jan-Feb;14(1):16-20. doi: 10.1016/j.tmaid.2016.01.012.

False positive dengue NS1 antigen test in a traveller with an acute Zika virus infection imported into Switzerland.
Gyurech D, Schilling J, Schmidt-Chanasit J, Cassinotti P, Kaeppeli F, Dobec M.
Swiss Med Wkly. 2016 Feb 9;146:w14296. doi: 10.4414/smw.2016.14296.

Reconstruction of the Evolutionary History and Dispersal of Usutu Virus, a Neglected Emerging Arbovirus in Europe and Africa.
Engel D, Jöst H, Wink M, Börstler J, Bosch S, Garigliany MM, Jöst A, Czajka C, Lühken R, Ziegler U, Groschup MH, Pfeffer M, Becker N, Cadar D, Schmidt-Chanasit J.
MBio. 2016 Feb 2;7(1). pii: e01938-15. doi: 10.1128/mBio.01938-15.

Pilot longitudinal mosquito surveillance study in the Danube Delta Biosphere Reserve and the first reports of Anopheles algeriensis Theobald, 1903 and Aedes hungaricus Mihályi, 1955 for Romania.
Török E, Tomazatos A, Cadar D, Horváth C, Keresztes L, Jansen S, Becker N, Kaiser A, Popescu O, Schmidt-Chanasit J, Jöst H, Lühken R.
Parasit Vectors. 2016 Apr 11;9(1):196. doi: 10.1186/s13071-016-1484-7.

Sustained Elevated Cytokine Levels during Recovery Phase of Mayaro Virus Infection.
Tappe D, Pérez-Girón JV, Just-Nübling G, Schuster G, Gómez-Medina S, Günther S, Muñoz-Fontela C, Schmidt-Chanasit J.
Emerg Infect Dis. 2016 Apr;22(4):750-2. doi: 10.3201/eid2204.151502.

Host-feeding patterns of mosquito species in Germany.
Börstler J, Jöst H, Garms R, Krüger A, Tannich E, Becker N, Schmidt-Chanasit J, Lühken R.
Parasit Vectors. 2016 Jun 3;9(1):318. doi: 10.1186/s13071-016-1597-z.

Surveillance of maternal antibodies against West Nile virus in chicken eggs in South-West Germany.
Börstler J, Engel D, Petersen M, Poggensee C, Jansen S, Schmidt-Chanasit J, Lühken R.
Trop Med Int Health. 2016 May;21(5):687-90. doi: 10.1111/tmi.12676.

Distribution of individual members of the mosquito Anopheles maculipennis complex in Germany identified by newly developed real-time PCR assays.
Lühken R, Czajka C, Steinke S, Jöst H, Schmidt-Chanasit J, Pfitzner W, Becker N, Kiel E, Krüger A, Tannich E.
Med Vet Entomol. 2016 Jun;30(2):144-54. doi: 10.1111/mve.12161.

New Hosts of The Lassa Virus.
Olayemi A, Cadar D, Magassouba N, Obadare A, Kourouma F, Oyeyiola A, Fasogbon S, Igbokwe J, Rieger T, Bockholt S, Jérôme H, Schmidt-Chanasit J, Garigliany M, Lorenzen S, Igbahenah F, Fichet JN, Ortsega D, Omilabu S, Günther S, Fichet-Calvet E.
Sci Rep. 2016 May 3;6:25280. doi: 10.1038/srep25280.

Indoor development of Aedes aegypti in Germany, 2016.
Kampen H, Jansen S, Schmidt-Chanasit J, Walther D.
Euro Surveill. 2016 Nov 24;21(47). pii: 30407. doi: 10.2807/1560-7917.ES.2016.21.47.30407.

Evidence for an independent third Usutu virus introduction into Germany.
Ziegler U, Fast C, Eiden M, Bock S, Schulze C, Hoeper D, Ochs A, Schlieben P, Keller M, Zielke DE, Luehken R, Cadar D, Walther D, Schmidt-Chanasit J, Groschup MH.
Vet Microbiol. 2016 Aug 30;192:60-6. doi: 10.1016/j.vetmic.2016.06.007.

2015 (selected)

Co-circulation of a novel phlebovirus and Massilia virus in sandflies, Portugal.
Amaro F, Zé-Zé L, Alves MJ, Börstler J, Clos J, Lorenzen S, Becker SC, Schmidt-Chanasit J, Cadar D.
Virol J. 2015 Oct 24;12:174. doi: 10.1186/s12985-015-0407-0.

Putative Lineage of Novel African Usutu Virus, Central Europe.
Cadar D, Bosch S, Jöst H, Börstler J, Garigliany MM, Becker N, Schmidt-Chanasit J.
Emerg Infect Dis. 2015 Sep [date cited]. http://dx.doi.org/10.3201/eid2109.142026

Zika virus infection in a traveller returning to Europe from Brazil, March 2015.
Zammarchi L, Tappe D, Fortuna C, Remoli ME, Gunther S, Venturi G, Bartoloni A, Schmidt-Chanasit J.
Euro Surveill. 2015 Jun 11;20(23). pii: 21153.

Acute Zika virus infection after travel to Malaysian Borneo, September 2014.
Tappe D, Nachtigall S, Kapaun A, Schnitzler P, Günther S, Schmidt-Chanasit J.
Emerg Infect Dis. 2015 May;21(5):911-3. doi: 10.3201/eid2105.141960.

Zika virus infections imported to Italy: clinical, immunological and virological findings, and public health implications.
Zammarchi L, Stella G, Mantella A, Bartolozzi D, Tappe D, Günther S, Oestereich L, Cadar D, Muñoz-Fontela C, Bartoloni A, Schmidt-Chanasit J.
J Clin Virol. 2015 Feb;63:32-5. doi: 10.1016/j.jcv.2014.12.005.

Surveillance of Batai virus in bovines from Germany.
Hofmann M, Wiethölter A, Blaha I, Jöst H, Heinemann P, Lehmann M, Miller T, Cadar D, Yanase T, Kley N, Eiden M, Groschup M, Schmidt-Chanasit J.
Clin Vaccine Immunol. 2015 Jun;22(6):672-3. doi: 10.1128/CVI.00082-15.

West Nile virus lineage 2 infection in a blood donor from Vienna, Austria, August 2014.
Jungbauer C, Hourfar MK, Stiasny K, Aberle SW, Cadar D, Schmidt-Chanasit J, Mayr WR.
J Clin Virol. 2015 Mar;64:16-9. doi: 10.1016/j.jcv.2015.01.003.

Characterization of a novel circo-like virus in Aedes vexans mosquitoes from Germany: evidence for a new genus within the family Circoviridae.
Garigliany MM, Börstler J, Jöst H, Badusche M, Desmecht D, Schmidt-Chanasit J, Cadar D.
J Gen Virol. 2015 Apr;96(Pt 4):915-20. doi: 10.1099/vir.0.000036.

Health care response to CCHF in US soldier and nosocomial transmission to health care providers, Germany, 2009.
Conger NG, Paolino KM, Osborn EC, Rusnak JM, Günther S, Pool J, Rollin PE, Allan PF, Schmidt-Chanasit J, Rieger T, Kortepeter MG.
Emerg Infect Dis. 2015 Jan;21(1):23-31. doi: 10.3201/eid2101.141413.

2014 (selected)

Usutu virus in bats, Germany, 2013.
Cadar D, Becker N, Campos Rde M, Börstler J, Jöst H, Schmidt-Chanasit J.
Emerg Infect Dis. 2014 Oct;20(10):1771-3. doi: 10.3201/eid2010.140909.

O'nyong-nyong virus infection imported to Europe from Kenya by a traveler.
Tappe D, Kapaun A, Emmerich P, Campos Rde M, Cadar D, Günther S, Schmidt-Chanasit J.
Emerg Infect Dis. 2014 Oct;20(10):1766-7. doi: 10.3201/eid2010.140823.

Zika virus infection after travel to Tahiti, December 2013.
Wæhre T, Maagard A, Tappe D, Cadar D, Schmidt-Chanasit J.
Emerg Infect Dis. 2014 Aug;20(8):1412-4. doi: 10.3201/eid2008.140302.

Dengue virus transmission by blood stem cell donor after travel to Sri Lanka; Germany, 2013.
Punzel M, Korukluoğlu G, Caglayik DY, Menemenlioglu D, Bozdag SC, Tekgündüz E, Altuntaş F, Campos Rde M, Burde B, Günther S, Tappe D, Cadar D, Schmidt-Chanasit J.
Emerg Infect Dis. 2014 Aug;20(8):1366-9. doi: 10.3201/eid2008.140508.

Genome analysis of Mayaro virus imported to Germany from French Guiana.
Friedrich-Jänicke B, Emmerich P, Tappe D, Günther S, Cadar D, Schmidt-Chanasit J.
Emerg Infect Dis. 2014 Jul;20(7):1255-7. doi: 10.3201/eid2007.140043.

First case of laboratory-confirmed Zika virus infection imported into Europe, November 2013.
Tappe D, Rissland J, Gabriel M, Emmerich P, Gunther S, Held G, Smola S, Schmidt-Chanasit J.
Euro Surveill. 2014 Jan 30;19(4). pii: 20685.

Autochthonous dengue virus infection in Japan imported into Germany, September 2013.
Schmidt-Chanasit J, Emmerich P, Tappe D, Gunther S, Schmidt S, Wolff D, Hentschel K, Sagebiel D, Schoneberg I, Stark K, Frank C.
Euro Surveill. 2014 Jan 23;19(3). pii: 20681.

Detection of Usutu virus in a bullfinch (Pyrrhula pyrrhula) and a great spotted woodpecker (Dendrocopos major) in north-west Europe.
Garigliany MM, Marlier D, Tenner-Racz K, Eiden M, Cassart D, Gandar F, Beer M, Schmidt-Chanasit J, Desmecht D.
Vet J. 2014 Jan;199(1):191-3. doi: 10.1016/j.tvjl.2013.10.017.

Dengue virus & co: are mosquito-borne viral diseases on the rise?
Cramer JP, Schmidt-Chanasit J.
Dtsch Med Wochenschr. 2014 Feb;139(6):247-50. doi: 10.1055/s-0033-1359968.

Cyclovirus CyCV-VN species distribution is not limited to Vietnam and extends to Africa.
Garigliany MM, Hagen RM, Frickmann H, May J, Schwarz NG, Perse A, Jöst H, Börstler J, Shahhosseini N, Desmecht D, Mbunkah HA, Daniel AM, Kingsley MT, de Mendonca Campos R, de Paula VS, Randriamampionona N, Poppert S, Tannich E, Rakotozandrindrainy R, Cadar D, Schmidt-Chanasit J.
Sci Rep. 2014 Dec 18;4:7552. doi: 10.1038/srep07552.

Lack of evidence for the presence of Schmallenberg virus in mosquitoes in Germany, 2011.
Wernike K, Jöst H, Becker N, Schmidt-Chanasit J, Beer M
Parasit Vectors. 2014 Aug 29;7:402. doi: 10.1186/1756-3305-7-402.

Arbeitsgruppe Schmidt-Chanasit (Arbovirologie)
2013 (selected)

Increase in West Nile virus infections imported to Germany in 2012.
Gabriel M, Emmerich P, Frank C, Fiedler M, Rashidi-Alavijeh J, Jochum C, Günther S, Auerhammer K, Rupprecht HJ, Blank RT, Sacher N, Pertzborn L, Stark K, Schrauzer T, Schmidt-Chanasit J.
J Clin Virol. 2013 Nov;58(3):587-9. doi: 10.1016/j.jcv.2013.08.027.

Emergence of Dengue virus 4 genotypes II b and I in the city of Rio de Janeiro.
Campos Rde M, Veiga CS, Meneses MD, de Souza LM, Fernandes CA, Malirat V, Albuquerque JP, Tanuri A, Schmidt-Chanasit J, Ferreira DF.
J Clin Virol. 2013 Jan;56(1):86-8. doi: 10.1016/j.jcv.2012.10.006.

Arbeitsgruppe Schmidt-Chanasit (Arbovirologie)
2012 (selected)

Epizootic emergence of Usutu virus in wild and captive birds in Germany.
Becker N, Jöst H, Ziegler U, Eiden M, Höper D, Emmerich P, Fichet-Calvet E, Ehichioya DU, Czajka C, Gabriel M, Hoffmann B, Beer M, Tenner-Racz K, Racz P, Günther S, Wink M, Bosch S, Konrad A, Pfeffer M, Groschup MH, Schmidt-Chanasit J.
PLoS One. 2012;7(2):e32604. doi: 10.1371/journal.pone.0032604.

West Nile virus meningoencephalitis imported into Germany.
Schultze-Amberger J, Emmerich P, Günther S, Schmidt-Chanasit J.
Emerg Infect Dis. 2012 Oct;18(10):1698-700. doi: 10.3201/eid1810.120204.

Two laboratory-confirmed cases of Japanese encephalitis imported to Germany by travelers returning from Southeast Asia.
Tappe D, Nemecek A, Zipp F, Emmerich P, Gabriel M, Günther S, Dobler G, Schmidt-Chanasit J, Stich A.
J Clin Virol. 2012 Jul;54(3):282-5. doi: 10.1016/j.jcv.2012.03.004.

Fatal dengue hemorrhagic fever imported into Germany.
Schmidt-Chanasit J, Tenner-Racz K, Poppert D, Emmerich P, Frank C, Dinges C, Penning R, Nerlich A, Racz P, Günther S.
Infection. 2012 Aug;40(4):441-3. doi: 10.1007/s15010-011-0208-3.

Detection of Usutu virus infection in a healthy blood donor from south-west Germany, 2012.
Allering L, Jöst H, Emmerich P, Günther S, Lattwein E, Schmidt M, Seifried E, Sambri V, Hourfar K, Schmidt-Chanasit J.
Euro Surveill. 2012 Dec 13;17(50). pii: 20341.

Seroprevalence of antibodies against Chikungunya, Dengue, and Rift Valley fever viruses after febrile illness outbreak, Madagascar.
Schwarz NG, Girmann M, Randriamampionona N, Bialonski A, Maus D, Krefis AC, Njarasoa C, Rajanalison JF, Ramandrisoa HD, Randriarison ML, May J, Schmidt-Chanasit J, Rakotozandrindrainy R.
Emerg Infect Dis. 2012 Nov;18(11):1780-6. doi: 10.3201/eid1811.111036.

Arbeitsgruppe Schmidt-Chanasit (Arbovirologie)
2011 (selected)

Isolation of usutu virus in Germany.
Jöst H, Bialonski A, Maus D, Sambri V, Eiden M, Groschup MH, Günther S, Becker N, Schmidt-Chanasit J.
Am J Trop Med Hyg. 2011 Sep;85(3):551-3. doi: 10.4269/ajtmh.2011.11-0248.

Medical importance of Sindbis virus in south-west Germany.
Jöst H, Bürck-Kammerer S, Hütter G, Lattwein E, Lederer S, Litzba N, Bock-Hensley O, Emmerich P, Günther S, Becker N, Niedrig M, Schmidt-Chanasit J.
J Clin Virol. 2011 Nov;52(3):278-9. doi: 10.1016/j.jcv.2011.08.002.

Isolation and phylogenetic analysis of Batai virus, Germany.
Jöst H, Bialonski A, Schmetz C, Günther S, Becker N, Schmidt-Chanasit J.
Am J Trop Med Hyg. 2011 Feb;84(2):241-3. doi: 10.4269/ajtmh.2011.10-0483.

Arbeitsgruppe Schmidt-Chanasit (Arbovirologie)
2010 (selected)

Isolation and phylogenetic analysis of Sindbis viruses from mosquitoes in Germany.
Jöst H, Bialonski A, Storch V, Günther S, Becker N, Schmidt-Chanasit J.
J Clin Microbiol. 2010 May;48(5):1900-3. doi: 10.1128/JCM.00037-10.

Alumni

Doctoral Thesis

Dr. med. Johannes Maximilian Friedrich (2019) : Host-feeding patterns of mosquito species in Iran. cum laude, University Medical Center Hamburg-Eppendorf

Dr. med. Sami Shihada (2018) : High genetic diversity and emergence of new lineages of dengue virus type 3 and 4 detected in german travellers, 2006-2015. magna cum laude, University Medical Center Hamburg-Eppendorf

Dr. rer. nat. Nariman Shahhosseini (2017) : Mosquito surveillance in Iran and Germany reveals new insights into arbovirus ecology and evolution. cum laude, University of Hamburg

Dr. med. Dimitri Engel (2017) : Reconstruction of the evolutionary history and dispersal of Usutu virus, a neglected emerging arbovirus in Europe and Africa. magna cum laude, University Medical Center Hamburg-Eppendorf

Dr. rer. nat. Jessica Börstler (2016) : Arboviruses in Germany: geographical distribution and the interaction between mosquitoes and vertebrates. magna cum laude, University of Hamburg

Dr. med. Ludger Allering (2016) : Detection of Usutu virus infection in a healthy blood donor from south-west Germany, 2012. magna cum laude, University Medical Center Hamburg-Eppendorf

Dr. rer. nat. Hanna Jöst (2013) : Surveillance of arboviruses in mosquitoes of Germany. magna cum laude, Heidelberg University, Ruperto Carola

Dr. rer. nat. Patrick Heinemann (2013) : The N terminus of Andes virus L protein suppresses mRNA and protein expression in mammalian cells. magna cum laude, University of Bremen

Dr. med. Karoline Bleymehl (2011) : Phenotypic and genetic characterization of varicella-zoster virus mutants resistant to acyclovir, brivudine and/or foscarnet. summa cum laude, Goethe University Frankfurt

Dr. med. Stefanie Mikolajczak (2010) : Nephropathia epidemica outbreak in Lower Franconia and the Eifel: molecular biological studies on the causative hantavirus species in summer/autumn 2007. magna cum laude, Goethe University Frankfurt