Our highlights

• Detection of Marburg Virus Disease in Guinea

  • Koundouno FR, Kafetzopoulou LE, Faye M, Renevey A, Soropogui B, Ifono K, Nelson EV, Kamano AA, Tolno C, Annibaldis G, Millimono SL, Camara J, Kourouma K, Doré A, Millimouno TE, Tolno FMB, Hinzmann J, Soubrier H, Hinrichs M, Thielebein A, Herzer G, Pahlmann M, Ki-Zerbo GA, Formenty P, Legand A, Wiley MR, Faye O, Diagne MM, Sall AA, Lemey P, Bah A, Günther S, Keita S, Duraffour S, Magassouba N. doi: 10.1056/NEJMc2120183. PMID: 35767445; PMCID: PMC7613962.
  • N Engl J Med. 386(26):2528-2530
  • 2022-06-30

• Virus persistence after recovery from acute Lassa fever in Nigeria: a 2-year interim analysis of a prospective longitudinal cohort study

  • Thielebein A, Ighodalo Y, Taju A, Olokor T, Omiunu R, Esumeh R, Ebhodaghe P, Ekanem A, Igenegbale G, Giwa R, Renevey A, Hinzmann J, Müller J, Pallasch E, Pahlmann M, Guedj J, Nwatuzor J, Femi Babatunde O, Adomeh DI, Asogun D, Akpede N, Okogbenin S, Günther S, Oestereich L, Duraffour S, Ogbaini-Emovon E. . . doi: 10.1016/S2666-5247(21)00178-6. Epub 2021 Nov 8. PMID: 35544114.
  • Lancet Microbe. 3(1):e32-e40
  • 2022-01-01

• Conformational changes in Lassa virus L protein associated with promoter binding and RNA synthesis activity.

  • Kouba T*, Vogel D*, Thorkelsson SR*, Quemin ERJ, Williams HM, Milewski M, Busch C, Günther S, Grünewald K, Rosenthal M#, Cusack S#. |Note: * equal contributing first authors, # equal contributing senior authors & co-corresponding authors
  • Nat Commun. 2021 Dec 2;12(1):7018. doi: 10.1038/s41467-021-27305-5.
  • 2021-12-02

• Factors associated with progression to death in patients with Lassa fever in Nigeria: an observational study

  • Strampe J, Asogun DA, Speranza E, Pahlmann M, Soucy A, Bockholt S, Pallasch E, Becker-Ziaja B, Duraffour S, Bhadelia N, Ighodalo Y, Oyakhilome J, Omomoh EO, Olokor T, Adomeh DI, Ikponwonsa O, Aire C, Tobin E, Akpede N, Okokhere PO, Okogbenin SA, Akpede GO, Muñoz-Fontela C, Ogbaini-Emovon E, Günther S, Connor JH, Oestereich L.
  • Lancet Infect Dis. 21(6):876-886
  • 2021-06-01

• Structure of a functional cap-binding domain in Rift Valley fever virus L protein.

  • Gogrefe N, Reindl S, Günther S, Rosenthal M.
  • PLoS Pathog. 2019 May 28;15(5):e1007829. doi: 10.1371/journal.ppat.1007829.
  • 2019-05-28

• Metagenomic sequencing at the epicenter of the Nigeria 2018 Lassa fever outbreak

  • Kafetzopoulou LE, Pullan ST, Lemey P, Suchard MA, Ehichioya DU, Pahlmann M, Thielebein A, Hinzmann J, Oestereich L, Wozniak DM, Efthymiadis K, Schachten D, Koenig F, Matjeschk J, Lorenzen S, Lumley S, Ighodalo Y, Adomeh DI, Olokor T, Omomoh E, Omiunu R, Agbukor J, Ebo B, Aiyepada J, Ebhodaghe P, Osiemi B, Ehikhametalor S, Akhilomen P, Airende M, Esumeh R, Muoebonam E, Giwa R, Ekanem A, Igenegbale G, Odigie G, Okonofua G, Enigbe R, Oyakhilome J, Yerumoh EO, Odia I, Aire C, Okonofua M, Atafo R, Tobin E, Asogun D, Akpede N, Okokhere PO, Rafiu MO, Iraoyah KO, Iruolagbe CO, Akhideno P, Erameh C, Akpede G, Isibor E, Naidoo D, Hewson R, Hiscox JA, Vipond R, Carroll MW, Ihekweazu C, Formenty P, Okogbenin S, Ogbaini-Emovon E, Günther S, Duraffour S
  • Science. 363(6422):74-77
  • 2019-01-04

• Structural and functional characterization of the Sin Nombre virus L protein

  • Meier K, Thorkelsson SR, Durieux Trouilleton Q, Vogel D, Yu D, Kosinski J, Cusack S, Malet H, Grünewald K, Quemin ERJ, Rosenthal M.
  • PLoS Pathog. 2023 Aug 7;19(8):e1011533. doi: 10.1371/journal.ppat.1011533. eCollection 2023 Aug.
  • 2023-08-07

• Passive Transfer of Animal-Derived Polyclonal Hyperimmune Antibodies Provides Protection of Mice from Lethal Lassa Virus Infection

  • Lisa Oestereich, Helena Müller-Kräuter, Elisa Pallasch, Thomas Strecker
  • Viruses 2023, 15(7), 1436
  • 2023-06-26

• Seroepidemiology of Lassa virus in pregnant women in Southern Nigeria: A prospective hospital-based cohort study

  • Kayem ND, Okogbenin S, Okoeguale J, Momoh M, Njoku A, Eifediyi R, Enodiana X, Ngwu H, Irhiogbe W, Ighodalo Y, Olokor T, Odigie G, Castle L, Duraffour S, Oestereich L, Dahal P, Ariana P, Gunther S, Horby P.
  • PLoS Negl Trop Dis. 2023 May 22;17(5):e0011354. doi: 10.1371/journal.pntd.0011354. eCollection 2023 May.
  • 2023-05-22

• A validated protocol to UV-inactivate SARS-CoV-2 and herpesvirus-infected cells

  • Soh TK, Pfefferle S, Wurr S, von Possel R, Oestereich L, Rieger T, Uetrecht C, Rosenthal M, Bosse JB.
  • PLoS One. 18(5):e0274065
  • 2023-05-10

• Focussed Assessment with Sonography in acute Lassa Fever (FASLa): Development of a point-of-care protocol and description of common ultrasound findings

  • Erameh CO, Koch T, Edeawe OI, Oestereich L, Omansen T, Jochum J, Adomeh DI, Ikponmwonsa O, Aire C, Pahlmann M, Asogun DA, Ogbaini-Emovon E, Okogbenin SA, Günther S, Ramharter M, Akideno PE, Kreuels B.
  • J Infect. 87(1):27-33
  • 2023-04-17

• Transplacental transfer of Lassa IgG antibodies in pregnant women in Southern Nigeria: A prospective hospital-based cohort study

  • Kayem ND, Okogbenin S, Okoeguale J, Eigbefoh J, Ikheloa J, Eifediyi R, Enodiana X, Olorogbogo OE, Aikpokpo I, Ighodalo Y, Olokor T, Odigie G, Castle L, Duraffour S, Oestereich L, Dahal P, Ariana P, Gunther S, Horby P.
  • PLoS Negl Trop Dis. 2023 Apr 13;17(4):e0011209. doi: 10.1371/journal.pntd.0011209. eCollection 2023 Apr.
  • 2023-04-13

• A prospective, multi-site, cohort study to estimate incidence of infection and disease due to Lassa fever virus in West African countries (the Enable Lassa research programme)-Study protocol

  • Penfold S, Adegnika AA, Asogun D, Ayodeji O, Azuogu BN, Fischer WA 2nd, Garry RF, Grant DS, Happi C, N'Faly M, Olayinka A, Samuels R, Sibley J, Wohl DA, Accrombessi M, Adetifa I, Annibaldis G, Camacho A, Dan-Nwafor C, Deha ARE, DeMarco J, Duraffour S, Goba A, Grais R, Günther S, Honvou ÉJJP, Ihekweazu C, Jacobsen C, Kanneh L, Momoh M, Ndiaye A, Nsaibirni R, Okogbenin S, Ochu C, Ogbaini E, Logbo ÉPMA, Sandi JD, Schieffelin JS, Verstraeten T, Vielle NJ, Yadouleton A, Yovo EK; Enable Protocol authorship group.
  • PLoS One. 2023 Mar 30;18(3):e0283643. doi: 10.1371/journal.pone.0283643. eCollection 2023.
  • 2023-03-30

• Circulation of Lassa virus across the endemic Edo-Ondo axis, Nigeria, with cross-species transmission between multimammate mice.

  • Adesina AS, Oyeyiola A, Obadare A, Igbokwe J, Abejegah C, Akhilomen P, Bangura U, Asogun D, Tobin E, Ayodeji O, Osoniyi O, Davis C, Thomson EC, Pahlmann M, Günther S, Fichet-Calvet E, Olayemi A.
  • Emerg Microbes Infect.
  • 2023-03-22

• Tumor cell integrin β4 and tumor stroma E-/P-selectin cooperatively regulate tumor growth in vivo

  • Genduso S, Freytag V, Schetler D, Kirchner L, Schiecke A, Maar H, Wicklein D, Gebauer F, Bröker K, Stürken C, Milde-Langosch K, Oliveira-Ferrer L, Ricklefs FL, Ewald F, Wolters-Eisfeld G, Riecken K, Unrau L, Krause L, Bohnenberger H, Offermann A, Perner S, Sebens S, Lamszus K, Diehl L, Linder S, Jücker M, Schumacher U, Lange T.
  • J Hematol Oncol. 2023 Mar 17;16(1):23. doi: 10.1186/s13045-023-01413-9.
  • 2023-03-07

• Isolation of Cells from Glioblastoma Multiforme Grade 4 Tumors for Infection with Zika Virus prME and ME Pseudotyped HIV-1

  • Pöhlking C, Beier S, Formanski JP, Friese M, Schreiber M, Schwalbe B
  • Int J Mol Sci. 24(5):4467
  • 2023-02-24

• Structural insights into viral genome replication by the severe fever with thrombocytopenia syndrome virus L protein

  • Williams HM, Thorkelsson SR, Vogel D, Milewski M, Busch C, Cusack S, Grünewald K, Quemin ERJ, Rosenthal M.
  • Nucleic Acids Res. 51(3):1424-1442
  • 2023-02-22

• An RNA to rule them all: Critical steps in Lassa virus ribonucleoparticle assembly and recruitment

  • Sänger L, Williams HM, Yu D, Vogel D, Kosinski J, Rosenthal M*, Uetrecht C*
  • BioRxiv Preprint
  • 2023-02-09

• Influence of Landscape Patterns on Exposure to Lassa Fever Virus, Guinea

  • Longet S, Leggio C, Bore JA, Key S, Tipton T, Hall Y, Koundouno FR, Bower H, Bhattacharyya T, Magassouba N, Günther S, Henao-Restrapo AM, Rossman JS, Konde MK, Fornace K, Carroll MW. . . doi: 10.3201/eid2902.212525. PMID: 36692336; PMCID: PMC9881776.
  • Emerg Infect Dis. 29(2):304-313
  • 2023-02-01

• The mechanism of genome replication and transcription in bunyaviruses.

  • Malet H, Williams HM, Cusack S, Rosenthal M.
  • PLoS Pathog. 2023 Jan 12;19(1):e1011060. doi: 10.1371/journal.ppat.1011060.
  • 2023-01-12

• AlphaPulldown – a Python package for protein-protein interaction screens using AlphaFold-Multimer.

  • Yu D, Chojnowski G, Rosenthal M, Kosinski J.
  • Bioinformatics. 2023 Jan 1;39(1):btac749. doi: 10.1093/bioinformatics/btac749.
  • 2023-01-01

• The East African Community's mobile laboratory network's rapid response during the first 2 weeks of the Ebola Sudan virus disease (SVD) outbreak in Uganda and pandemic preparedness activities in South Sudan, Rwanda, Tanzania, Burundi, Kenya

  • Gehre F, Lagu H, Achol E, Omari N, Ochido G, Duraffour S, Hinzmann J, Kezakarayagwa E, Kabatesi F, Nkeshimana A, Nyandwi J, Samson DD, Nykwec GA, Lokore ML, Deng LL, Kelly ME, Mkama PBM, Magesa A, Beyanga M, Roba A, Ndia M, Lokamar P, Kiiru J, Kabanda A, Mukagatare I, Kabalisa E, Rutayisire R, Sewanyana I, Nambozo EJ, Muyigi T, Pimundu G, May J, Katende M, Nabadda S, Nzeyimana E, Affara M.
  • BMJ Glob Health. 2022 Dec;7(12):e011073. doi: 10.1136/bmjgh-2022-011073.
  • 2022-12-16

• Lessons from the pandemic: Responding to emerging zoonotic viral diseases-a Keystone Symposia report

  • Cable J, Fauci A, Dowling WE, Günther S, Bente DA, Yadav PD, Madoff LC, Wang LF, Arora RK, Van Kerkhove M, Chu MC, Jaenisch T, Epstein JH, Frost SDW, Bausch DG, Hensley LE, Bergeron É, Sitaras I, Gunn MD, Geisbert TW, Muñoz-Fontela C, Krammer F, de Wit E, Nordenfelt P, Saphire EO, Gilbert SC, Corbett KS, Branco LM, Baize S, van Doremalen N, Krieger MA, Clemens SAC, Hesselink R, Hartman D.
  • Ann N Y Acad Sci. 1518(1):209-225
  • 2022-12-01

• An introduction to the Marburg virus vaccine consortium, MARVAC

  • Cross RW, Longini IM, Becker S, Bok K, Boucher D, Carroll MW, Díaz JV, Dowling WE, Draghia-Akli R, Duworko JT, Dye JM, Egan MA, Fast P, Finan A, Finch C, Fleming TR, Fusco J, Geisbert TW, Griffiths A, Günther S, Hensley LE, Honko A, Hunegnaw R, Jakubik J, Ledgerwood J, Luhn K, Matassov D, Meshulam J, Nelson EV, Parks CL, Rustomjee R, Safronetz D, Schwartz LM, Smith D, Smock P, Sow Y, Spiropoulou CF, Sullivan NJ, Warfield KL, Wolfe D, Woolsey C, Zahn R, Henao-Restrepo AM, Muñoz-Fontela C, Marzi A.
  • PLoS Pathog. 18(10)
  • 2022-10-13

• Clinical efficacy and in vitro neutralization capacity of monoclonal antibodies for severe acute respiratory syndrome coronavirus 2 delta and omicron variants

  • Brehm TT, Pfefferle S, von Possel R, Karolyi M, Zoufaly A, Wichmann D, Kobbe R, Emmerich P, Nörz D, Aepfelbacher M, Schulze Zur Wiesch J, Addo MM, Schmiedel S, Lütgehetmann M.
  • J Med Virol. 94(10):5038-5043
  • 2022-10-01

• Predicting the evolution of the Lassa virus endemic area and population at risk over the next decades

  • Klitting R, Kafetzopoulou LE, Thiery W, Dudas G, Gryseels S, Kotamarthi A, Vrancken B, Gangavarapu K, Momoh M, Sandi JD, Goba A, Alhasan F, Grant DS, Okogbenin S, Ogbaini-Emovo E, Garry RF, Smither AR, Zeller M, Pauthner MG, McGraw M, Hughes LD, Duraffour S, Günther S, Suchard MA, Lemey P, Andersen KG, Dellicour S.
  • Nat Commun. 2022 Sep 27;13(1):5596. doi: 10.1038/s41467-022-33112-3.
  • 2022-09-27

• Two Cases of Lassa Fever Successfully Treated with Ribavirin and Adjunct Dexamethasone for Concomitant Infections

  • Okogbenin S, Erameh C, Okoeguale J, Edeawe O, Ekuaze E, Iraoyah K, Agho J, Groger M, Kreuels B, Oestereich L, Babatunde FO, Akhideno P, Günther S, Ramharter M, Omansen T.
  • Emerg Infect Dis. 2022 Oct;28(10):2060-2063. doi: 10.3201/eid2810.220625.
  • 2022-09-23

• Understanding Host-Virus Interactions: Assessment of Innate Immune Responses in Mastomys natalensis Cells after Arenavirus Infection

  • Brinkmann NM, Hoffmann C, Wurr S, Pallasch E, Hinzmann J, Ostermann E, Brune W, Eskes ME, Jungblut L, Günther S, Unrau L, Oestereich L.
  • Viruses. 2022 Sep 8;14(9):1986. doi: 10.3390/v14091986.
  • 2022-09-23

• Avatar Mice Underscore the Role of the T Cell-Dendritic Cell Crosstalk in Ebola Virus Disease and Reveal Mechanisms of Protection in Survivors

  • Rottstegge M, Tipton T, Oestereich L, Ruibal P, Nelson EV, Olal C, Port JR, Seibel J, Pallasch E, Bockholt S, Koundouno FR, Boré JA, Rodríguez E, Escudero-Pérez B, Günther S, Carroll MW, Muñoz-Fontela C.
  • J Virol. 2022 Sep 28;96(18):e0057422. doi: 10.1128/jvi.00574-22. Epub 2022 Sep 8.
  • 2022-09-08

• Anti-SARS-CoV-2 antibodies in breast milk during lactation after infection or vaccination: A cohort study

  • Olearo F, Radmanesh LS, Felber N, von Possel R, Emmerich P, Pekarek N, Pfefferle S, Nörz D, Hansen G, Diemert A, Aepfelbacher M, Hecher K, Lütgehetmann M, Arck PC, Tallarek AC.
  • J Reprod Immunol. 153:103685
  • 2022-09-01

• Rapid Adaptation of Established High-Throughput Molecular Testing Infrastructure for Monkeypox Virus Detection

  • Nörz D, Tang HT, Emmerich P, Giersch K, Fischer N, Schmiedel S, Addo MM, Aepfelbacher M, Pfefferle S, Lütgehetmann M. . . doi: 10.3201/eid2809.220917. Epub 2022 Jul 29. PMID: 35905463; PMCID: PMC9423910.
  • Emerg Infect Dis. 28(9):1765-1769
  • 2022-09-01

• Establishment of Recombinant Trisegmented Mopeia Virus Expressing Two Reporter Genes for Screening of Mammarenavirus Inhibitors

  • Oestereich L, Wurr S, Becker-Ziaja B, Bockholt S, Pahlmann M, Cadar D, Kümmerer BM, Günther S, Kerber R
  • Viruses. 2022 Aug 25;14(9):1869
  • 2022-08-18

• Pharmacokinetics of Ribavirin in the Treatment of Lassa Fever: An Observational Clinical Study at the Irrua Specialist Teaching Hospital, Edo State, Nigeria

  • Groger M, Akhideno P, Kleist CJ, Babatunde FO, Edeawe O, Hinzmann J, Akhigbe T, Nwatuzor J, Eifediyi G, Müller J, Hinrichs M, Pahlmann M, Sarpong FN, Wagner C, Thielebein A, Aihonwalan L, Koch T, Riedner M, Ogbaini-Emovon E, Okogbenin S, Günther S, Wicha SG, Ramharter M, Oestereich L, Duraffour S, Erameh C.
  • Clin Infect Dis. 76(3):e841-e848
  • 2022-07-26

• Detection of Marburg Virus Disease in Guinea

  • Koundouno FR, Kafetzopoulou LE, Faye M, Renevey A, Soropogui B, Ifono K, Nelson EV, Kamano AA, Tolno C, Annibaldis G, Millimono SL, Camara J, Kourouma K, Doré A, Millimouno TE, Tolno FMB, Hinzmann J, Soubrier H, Hinrichs M, Thielebein A, Herzer G, Pahlmann M, Ki-Zerbo GA, Formenty P, Legand A, Wiley MR, Faye O, Diagne MM, Sall AA, Lemey P, Bah A, Günther S, Keita S, Duraffour S, Magassouba N. doi: 10.1056/NEJMc2120183. PMID: 35767445; PMCID: PMC7613962.
  • N Engl J Med. 386(26):2528-2530
  • 2022-06-30

• Detection of Lassa Virus-Reactive IgG Antibodies in Wild Rodents: Validation of a Capture Enzyme-Linked Immunological Assay

  • Soubrier H, Bangura U, Hoffmann C, Olayemi A, Adesina AS, Günther S, Oestereich L, Fichet-Calvet E.
  • Viruses. 2022 May 7;14(5):993. doi: 10.3390/v14050993.
  • 2022-05-28

• Fcγ-Receptor-Based Enzyme-Linked Immunosorbent Assays for Sensitive, Specific, and Persistent Detection of Anti-SARS-CoV-2 Nucleocapsid Protein IgG Antibodies in Human Sera

  • Deschermeier C, Ehmen C, von Possel R, Murawski C, Rushton B, Amuasi J, Sarpong N, Maiga-Ascofaré O, Rakotozandrindrainy R, Asogun D, Ighodalo Y, Oestereich L, Duraffour S, Pahlmann M, Emmerich P.
  • J Clin Microbiol. 60(6):e0007522
  • 2022-05-16

• Virus persistence after recovery from acute Lassa fever in Nigeria: a 2-year interim analysis of a prospective longitudinal cohort study

  • Thielebein A, Ighodalo Y, Taju A, Olokor T, Omiunu R, Esumeh R, Ebhodaghe P, Ekanem A, Igenegbale G, Giwa R, Renevey A, Hinzmann J, Müller J, Pallasch E, Pahlmann M, Guedj J, Nwatuzor J, Femi Babatunde O, Adomeh DI, Asogun D, Akpede N, Okogbenin S, Günther S, Oestereich L, Duraffour S, Ogbaini-Emovon E.
  • Lancet Microbe. 2022 Jan;3(1):e32-e40. doi: 10.1016/S2666-5247(21)00178-6. Epub 2021 Nov 8.
  • 2022-05-11

• Access and benefit-sharing by the European Virus Archive in response to COVID-19

  • Sett S, Dos Santos Ribeiro C, Prat C, Haringhuizen G; European Virus Archive principal investigators; Scholz AH. . . doi: 10.1016/S2666-5247(21)00211-1. Epub 2021 Nov 16. Erratum in: Lancet Microbe. 2022 Jan;3(1):e8. PMID: 34806057; PMCID: PMC8594928.
  • Lancet Microbe. 3(4):e316-e323
  • 2022-04-01

• Conformational changes in Lassa virus L protein associated with promoter binding and RNA synthesis activity.

  • Kouba T*, Vogel D*, Thorkelsson SR*, Quemin ERJ, Williams HM, Milewski M, Busch C, Günther S, Grünewald K, Rosenthal M#, Cusack S#. |Note: * equal contributing first authors, # equal contributing senior authors & co-corresponding authors
  • Nat Commun. 2021 Dec 2;12(1):7018. doi: 10.1038/s41467-021-27305-5.
  • 2021-12-02

• Conserved E1B-55K SUMOylation in different human adenovirus species is a potent regulator of intracellular localization

  • Kolbe V, Ip WH, Kieweg-Thompson L, Lang J, Gruhne J, Meyer T, Wilkens B, Schie M, Thünauer R, Schreiner S, Bertzbach LD, Rodríguez E, Dobner T
  • J Virol. 2022 Feb 9;96(3):e0083821. doi: 10.1128/JVI.00838-21
  • 2021-11-17

• Smad7 Deficiency in Myeloid Cells Does Not Affect Liver Injury, Inflammation or Fibrosis after Chronic CCl(4) Exposure in Mice

  • Unrau L, Endig J, Goltz D, Sprezyna P, Ulrich H, Hagenstein J, Geers B, Kaftan K, Heukamp LC, Tiegs G, Diehl L.
  • Int J Mol Sci. 2021 Oct 27;22(21):11575. doi: 10.3390/ijms222111575.
  • 2021-11-13

• Comparative sensitivity evaluation for 122 CE-marked rapid diagnostic tests for SARS-CoV-2 antigen, Germany, September 2020 to April 2021

  • Scheiblauer H, Filomena A, Nitsche A, Puyskens A, Corman VM, Drosten C, Zwirglmaier K, Lange C, Emmerich P, Müller M, Knauer O, Nübling CM. . :2100441. doi: 10.2807/1560-7917.ES.2021.26.44.2100441. Erratum in: Euro Surveill. 2022 Jan;27(3): PMID: 34738515; PMCID: PMC8569926.
  • Euro Surveill. 26(44)
  • 2021-11-01

• Establishment of a specimen panel for the decentralised technical evaluation of the sensitivity of 31 rapid diagnostic tests for SARS-CoV-2 antigen, Germany, September 2020 to April 2021

  • Puyskens A, Krause E, Michel J, Nübling CM, Scheiblauer H, Bourquain D, Grossegesse M, Valusenko R, Corman VM, Drosten C, Zwirglmaier K, Wölfel R, Lange C, Kramer J, Friesen J, Ignatius R, Müller M, Schmidt-Chanasit J, Emmerich P, Schaade L, Nitsche A.
  • Euro Surveill. 26(44):2100442
  • 2021-11-01

• Neutralization of Dengue Virus Serotypes by Sera from Dengue-Infected Individuals Is Preferentially Directed to Heterologous Serotypes and Not against the Autologous Serotype Present in Acute Infection

  • Auerswald H, Kann S, Klepsch L, Hülsemann J, Rudnik I, Schreiber S, Buchy P, Schreiber M.
  • Viruses. 13(10):1957
  • 2021-09-29

• Hepatitis C Virus sub-Saharan Africa Network. Hepatitis C virus in sub-Saharan Africa: a long road to elimination

  • Shah R, Agyei-Nkansah A, Alikah F, Asamoah-Akuoko L, Bagou YCO, Dhiblawe A, Ehichioya D, Finch PJ, Katsidzira L, Kodjoh N, Kpossou RA, Lakoh S, Makuza JD, Marowa L, Ndububa DA, Mbendi CN, Nyirenda M, Ocama P, Opio CK, Seremba E, Shindano TA, Thomson EC
  • Lancet Gastroenterol Hepatol. 6(9):693-694
  • 2021-09-01

• Impact of Dose, Duration, and Immune Status on Efficacy of Ultrashort Telacebec Regimens in Mouse Models of Buruli Ulcer.

  • Komm O, Almeida DV, Converse PJ, Omansen TF, Nuermberger EL.
  • Antimicrob Agents Chemother. 2021 Oct 18;65(11):e0141821. doi: 10.1128/AAC.01418-21. Epub 2021 Aug 30.
  • 2021-08-30

• Hantavirus Replication Cycle – An Updated Structural Virology Perspective.

  • Meier K, Thorkelsson SR, Quemin E*, Rosenthal M*
  • Viruses
  • 2021-08-06

• The East African Community (EAC) mobile laboratory networks in Kenya, Burundi, Tanzania, Rwanda, Uganda, and South Sudan-from project implementation to outbreak response against Dengue, Ebola, COVID-19, and epidemic-prone diseases

  • Affara M, Lagu HI, Achol E, Karamagi R, Omari N, Ochido G, Kezakarayagwa E, Kabatesi F, Nkeshimana A, Roba A, Ndia MN, Abudo MU, Kabanda A, Mpabuka E, Mwikarago EI, Kutjok PE, Samson DD, Deng LL, Moremi N, Kelly ME, Mkama PBM, Magesa A, Balinandi SK, Pimundu G, Nabadda SN, Puradiredja DI, Hinzmann J, Duraffour S, Gabriel M, Ruge G, Loag W, Ayiko R, Sonoiya SS, May J, Katende MJ, Gehre F.
  • BMC Med. 2021 Jul 9;19(1):160. doi: 10.1186/s12916-021-02028-y.
  • 2021-07-09

• Experimental Morogoro Virus Infection in Its Natural Host, Mastomys natalensis

  • Hoffmann C, Wurr S, Pallasch E, Bockholt S, Rieger T, Günther S, Oestereich L.
  • Viruses. 2021 May 7;13(5):851. doi: 10.3390/v13050851.
  • 2021-06-02

• Validation of Inactivation Methods for Arenaviruses

  • Olschewski S, Thielebein A, Hoffmann C, Blake O, Müller J, Bockholt S, Pallasch E, Hinzmann J, Wurr S, Neddersen N, Rieger T, Günther S, Oestereich L.
  • Viruses. 2021 May 24;13(6):968. doi: 10.3390/v13060968.
  • 2021-06-02

• Factors associated with progression to death in patients with Lassa fever in Nigeria: an observational study

  • Strampe J, Asogun DA, Speranza E, Pahlmann M, Soucy A, Bockholt S, Pallasch E, Becker-Ziaja B, Duraffour S, Bhadelia N, Ighodalo Y, Oyakhilome J, Omomoh EO, Olokor T, Adomeh DI, Ikponwonsa O, Aire C, Tobin E, Akpede N, Okokhere PO, Okogbenin SA, Akpede GO, Muñoz-Fontela C, Ogbaini-Emovon E, Günther S, Connor JH, Oestereich L.
  • Lancet Infect Dis. 21(6):876-886
  • 2021-06-01

• X-ray screening identifies active site and allosteric inhibitors of SARS-CoV-2 main protease.

  • Günther S†*, Reinke PYA†, Fernández-García Y, Lieske J, Lane TJ, Ginn HM, Koua FHM, Ehrt C, Ewert W, Oberthuer D, Yefanov O, Meier S, Lorenzen K, Krichel B, Kopicki JD, Gelisio L, Brehm W, Dunkel I, Seychell B, Gieseler H, Norton-Baker B, Escudero-Pérez B, Domaracky M, Saouane S, Tolstikova A, White TA, Hänle A, Groessler M, Fleckenstein H, Trost F, Galchenkova M, Gevorkov Y, Li C, Awel S, Peck A, Barthelmess M, Schlünzen F, Lourdu Xavier P, Werner N, Andaleeb H, Ullah N, Falke S, Srinivasan V, França BA, Schwinzer M, Brognaro H, Rogers C, Melo D, Zaitseva-Doyle JJ, Knoska J, Peña-Murillo GE, Mashhour AR, Hennicke V, Fischer P, Hakanpää J, Meyer J, Gribbon P, Ellinger B, Kuzikov M, Wolf M, Beccari AR, Bourenkov G, von Stetten D, Pompidor G, Bento I, Panneerselvam S, Karpics I, Schneider TR, Garcia-Alai MM, Niebling S, Günther C, Schmidt C, Schubert R, Han H, Boger J, Monteiro DCF, Zhang L, Sun X, Pletzer-Zelgert J, Wollenhaupt J, Feiler CG, Weiss MS, Schulz EC, Mehrabi P, Karničar K, Usenik A, Loboda J, Tidow H, Chari A, Hilgenfeld R, Uetrecht C, Cox R, Zaliani A, Beck T, Rarey M, Günther S, Turk D, Hinrichs W, Chapman HN, Pearson AR, Betzel C, Meents A* |Note: † equal contributing first authors, * equal contributing corresponding authors.
  • Science. 372(6542): 642-646. doi:10.1126/science.abf7945.
  • 2021-04-02

• Errors in the deposited SFTSV L protein structure.

  • Cusack S, Rosenthal M.
  • Nat Microbiol. 2021 May;6(5):549-550. doi: 10.1038/s41564-021-00901-3.
  • 2021-05-06

• The niche of One Health approaches in Lassa fever surveillance and control

  • Arruda LB, Haider N, Olayemi A, Simons D, Ehichioya D, Yinka-Ogunleye A, Ansumana R, Thomason MJ, Asogun D, Ihekweazu C, Fichet-Calvet E, Kock RA. . . doi: 10.1186/s12941-021-00431-0. PMID: 33894784; PMCID: PMC8067790.
  • Ann Clin Microbiol Antimicrob. 20(1):29
  • 2021-04-24

• Reduced Nucleoprotein Availability Impairs Negative-Sense RNA Virus Replication and Promotes Host Recognition.

  • Nilsson-Payant BE, Blanco-Melo D, Uhl S, Escudero-Pérez B, Olschewski S, Thibault P, Panis M, Rosenthal M, Muñoz-Fontela C, Lee B, tenOever BR.
  • J Virol. 2021 Apr 12;95(9):e02274-20. doi: 10.1128/JVI.02274-20.
  • 2021-04-12

• SARS-CoV-2 Reinfection in a Healthcare Worker Despite the Presence of Detectable Neutralizing Antibodies

  • Brehm TT, Pfefferle S, von Possel R, Kobbe R, Nörz D, Schmiedel S, Grundhoff A, Olearo F, Emmerich P, Robitaille A, Günther T, Braun P, Andersen G, Knobloch JK, Addo MM, Lohse AW, Aepfelbacher M, Fischer N, Schulze Zur Wiesch J, Lütgehetmann M. . . doi: 10.3390/v13040661. PMID: 33921216; PMCID: PMC8070424.
  • Viruses. 13(4):661
  • 2021-04-12

• Lassa fever outcomes and prognostic factors in Nigeria (LASCOPE): a prospective cohort study

  • Duvignaud A, Jaspard M, Etafo IC, Gabillard D, Serra B, Abejegah C, le Gal C, Abidoye AT, Doutchi M, Owhin S, Séri B, Vihundira JK, Bérerd-Camara M, Schaeffer J, Danet N, Augier A, Ogbaini-Emovon E, Salam AP, Ahmed LA, Duraffour S, Horby P, Günther S, Adedosu AN, Ayodeji OO, Anglaret X, Malvy D; LASCOPE study group.
  • Lancet Glob Health. 2021 Apr;9(4):e469-e478. doi: 10.1016/S2214-109X(20)30518-0.
  • 2021-03-19

• Handling and accuracy of four rapid antigen tests for the diagnosis of SARS-CoV-2 compared to RT-qPCR

  • Olearo F, Nörz D, Heinrich F, Sutter JP, Roedl K, Schultze A, Wiesch JSZ, Braun P, Oestereich L, Kreuels B, Wichmann D, Aepfelbacher M, Pfefferle S, Lütgehetmann M.
  • J Clin Virol. 2021 Apr;137:104782. doi: 10.1016/j.jcv.2021.104782. Epub 2021 Mar 3.
  • 2021-03-12

• Limited specificity of commercially available SARS-CoV-2 IgG ELISAs in serum samples of African origin

  • Emmerich P, Murawski C, Ehmen C, von Possel R, Pekarek N, Oestereich L, Duraffour S, Pahlmann M, Struck N, Eibach D, Krumkamp R, Amuasi J, Maiga-Ascofaré O, Rakotozandrindrainy R, Asogun D, Ighodalo Y, Kann S, May J, Tannich E, Deschermeier C.
  • Trop Med Int Health. 26(6):621-631
  • 2021-03-05

• Heterologous arenavirus vector prime-boost overrules self-tolerance for efficient tumor-specific CD8 T cell attack

  • Bonilla WV, Kirchhammer N, Marx AF, Kallert SM, Krzyzaniak MA, Lu M, Darbre S, Schmidt S, Raguz J, Berka U, Vincenti I, Pauzuolis M, Kerber R, Hoepner S, Günther S, Magnus C, Merkler D, Orlinger KK, Zippelius A, Pinschewer DD. . . doi: 10.1016/j.xcrm.2021.100209. PMID: 33763654; PMCID: PMC7974551.
  • Cell Rep Med. 2(3):100209
  • 2021-03-03

• First Serological Evidence of West Nile Virus Among Equines and Birds in Kosovo, 2018-2019

  • Rexhepi A, Sherifi K, Berxholi K, Xhekaj B, Muja-Bajraktari N, Özkul A, von Possel R, Emmerich P. . . doi: 10.1089/vbz.2020.2673. Epub 2020 Oct 21. PMID: 33090084.
  • Vector Borne Zoonotic Dis. 21(2):116-120
  • 2021-02-01

• N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease

  • Koudelka T, Boger J, Henkel A, Schönherr R, Krantz S, Fuchs S, Rodríguez E, Redecke L, Tholey A
  • Proteomics. 2021 Jan;21(2):e2000246. doi: 10.1002/pmic.202000246
  • 2021-01-01

• Human Diversity of Killer Cell Immunoglobulin-Like Receptors and Human Leukocyte Antigen Class I Alleles and Ebola Virus Disease Outcomes

  • Wawina-Bokalanga T, Vanmechelen B, Lhermitte V, Martí-Carreras J, Vergote V, Koundouno FR, Akoi-Boré J, Thom R, Tipton T, Steeds K, Moussa KB, Amento A, Laenen L, Duraffour S, Gabriel M, Ruibal P, Hall Y, Kader-Kondé M, Günther S, Baele G, Muñoz-Fontela C, Van Weyenbergh J, Carroll MW, Maes P.
  • Emerg Infect Dis. 2021 Jan;27(1):76-84. doi: 10.3201/eid2701.202177.
  • 2020-12-22

• Diketo acids inhibit the cap-snatching endonuclease of several Bunyavirales.

  • Fernández-García Y†*, Ter Horst S†, Bassetto M, Brancale A, Neyts J, Rogolino D, Sechi M, Carcelli M, Günther S, Rocha-Pereira J* |Note: † equal contributing first authors, * equal contributing corresponding authors.
  • Antiviral Research. 183: 104947. doi:10.1016/j.antiviral.2020.104947.
  • 2020-09-24

• Enhanced efficacy of endonuclease inhibitor baloxavir acid against orthobunyaviruses when used in combination with ribavirin.

  • Ter Horst S†, Fernandez-Garcia Y†*, Bassetto M, Günther S, Brancale A, Neyts J, Rocha-Pereira J* |Note: † equal contributing first authors, * equal contributing corresponding authors.
  • Journal of Antimicrobial Chemotherapy. 75(11): 3189–3193. doi:10.1093/jac/dkaa337.
  • 2020-08-07

• Evaluating case definitions for Ebola virus disease

  • Ramharter M, Günther S. . . doi: 10.1016/S1473-3099(20)30272-3. Epub 2020 Jun 25. PMID: 32593319; PMCID: PMC7316455.
  • Lancet Infect Dis. 20(11):1224-1226
  • 2020-11-01

• Longitudinal antibody and T cell responses in Ebola virus disease survivors and contacts: an observational cohort study

  • Thom R, Tipton T, Strecker T, Hall Y, Akoi Bore J, Maes P, Raymond Koundouno F, Fehling SK, Krähling V, Steeds K, Varghese A, Bailey G, Matheson M, Kouyate S, Coné M, Moussa Keita B, Kouyate S, Richard Ablam A, Laenen L, Vergote V, Guiver M, Timothy J, Atkinson B, Ottowell L, Richards KS, Bosworth A, Longet S, Mellors J, Pannetier D, Duraffour S, Muñoz-Fontela C, Sow O, Koivogui L, Newman E, Becker S, Sprecher A, Raoul H, Hiscox J, Henao-Restrepo AM, Sakoba K, Magassouba N, Günther S, Kader Konde M, Carroll MW.
  • Lancet Infect Dis. 2021 Apr;21(4):507-516. doi: 10.1016/S1473-3099(20)30736-2. Epub 2020 Oct 13.
  • 2020-10-16

• A Sporadic and Lethal Lassa Fever Case in Forest Guinea, 2019

  • Magassouba N, Koivogui E, Conde S, Kone M, Koropogui M, Soropogui B, Kekoura I, Hinzmann J, Günther S, Keita S, Duraffour S, Fichet-Calvet E.
  • Viruses. 2020 Sep 23;12(10):1062. doi: 10.3390/v12101062.
  • 2020-09-26

• Animal models for COVID-19

  • Muñoz-Fontela C, Dowling WE, Funnell SGP, Gsell PS, Riveros-Balta AX, Albrecht RA, Andersen H, Baric RS, Carroll MW, Cavaleri M, Qin C, Crozier I, Dallmeier K, de Waal L, de Wit E, Delang L, Dohm E, Duprex WP, Falzarano D, Finch CL, Frieman MB, Graham BS, Gralinski LE, Guilfoyle K, Haagmans BL, Hamilton GA, Hartman AL, Herfst S, Kaptein SJF, Klimstra WB, Knezevic I, Krause PR, Kuhn JH, Le Grand R, Lewis MG, Liu WC, Maisonnasse P, McElroy AK, Munster V, Oreshkova N, Rasmussen AL, Rocha-Pereira J, Rockx B, Rodríguez E, Rogers TF, Salguero FJ, Schotsaert M, Stittelaar KJ, Thibaut HJ, Tseng CT, Vergara-Alert J, Beer M, Brasel T, Chan JFW, García-Sastre A, Neyts J, Perlman S, Reed DS, Richt JA, Roy CJ, Segalés J, Vasan SS, Henao-Restrepo AM, Barouch DH
  • Nature. 2020 Oct;586(7830):509-515. doi: 10.1038/s41586-020-2787-6
  • 2020-09-23

• Variation around the dominant viral genome sequence contributes to viral load and outcome in patients with Ebola virus disease

  • Dong X, Munoz-Basagoiti J, Rickett NY, Pollakis G, Paxton WA, Günther S, Kerber R, Ng LFP, Elmore MJ, Magassouba N, Carroll MW, Matthews DA, Hiscox JA
  • Genome Biol. 21(1):238
  • 2020-09-07

• Mütter-Screening in einem COVID-19-Niedrig-Pandemiegebiet: Bestimmung SARS-CoV-2-spezifischer Antikörper bei 401 Rostocker Müttern mittels ELISA und Immunfluoreszenz-Bestätigungstest [Screening of Mothers in a COVID-19 Low-Prevalence Region: Determination of SARS-CoV-2 Antibodies in 401 Mothers from Rostock by ELISA and Confirmation by Immunofluorescence]

  • Reisinger EC, von Possel R, Warnke P, Geerdes-Fenge HF, Hemmer CJ, Pfefferle S, Löbermann M, Littmann M, Emmerich P
  • Dtsch Med Wochenschr. 145(17):e96-e100
  • 2020-08-01

• Clinical Management of Argentine Hemorrhagic Fever using Ribavirin and Favipiravir, Belgium, 2020

  • Veliziotis I, Roman A, Martiny D, Schuldt G, Claus M, Dauby N, Van den Wijngaert S, Martin C, Nasreddine R, Perandones C, Mahieu R, Swaan C, Van Praet S, Konopnicki D, Morales MA, Malvy D, Stevens E, Dechamps P, Vlieghe E, Vandenberg O, Günther S, Gérard M
  • Emerg Infect Dis. 26(7):1562-1566
  • 2020-07-01

• Lassa fever clinical course and setting a standard of care for future randomized trials: A protocol for a cohort study of Lassa-infected patients in Nigeria (LASCOPE)

  • Duvignaud A, Jaspard M, Etafo IC, Serra B, Abejegah C, Gabillard D, Doutchi M, Alabi JF, Adedokun MA, Akinpelu AO, Oyegunle OO, Etafo J, Dede AO, Onyechi MN, Ireneh MU, Gbenga-Ayeni O, Fadiminiyi KG, Ehigbor PI, Ouattara E, Levy-Marchal C, Karcher S, N'guessan-Koffi L, Ahyi I, Amani E, Diabaté M, Siloué B, Schaeffer J, Augier A, Ogbaini-Emovon E, Salam AP, Horby P, Ahmed LA, Günther S, Adedosu AN, Anglaret X, Ayodeji OO, Malvy D
  • Travel Med Infect Dis. 36:101557
  • 2020-07-01

• Structural and functional characterization of the severe fever with thrombocytopenia syndrome virus L protein

  • Vogel D, Thorkelsson SR, Quemin ERJ, Meier K, Kouba T, Gogrefe N, Busch C, Reindl S, Günther S, Cusack S, Grünewald K, Rosenthal M
  • Nucleic Acids Res. 48(10):5749-5765
  • 2020-06-04

• Safety, reactogenicity, and immunogenicity of a chimpanzee adenovirus vectored Ebola vaccine in adults in Africa: a randomised, observer-blind, placebo-controlled, phase 2 trial

  • Tapia MD, Sow SO, Ndiaye BP, Mbaye KD, Thiongane A, Ndour CT, Mboup S, Ake JA, Keshinro B, Akintunde GA, Kinge TN, Vernet G, Bigna JJ, Oguche S, Koram KA, Asante KP, Hogrefe WR, Günther S, Naficy A, De Ryck I, Debois M, Bourguignon P, Jongert E, Ballou WR, Koutsoukos M, Roman F, Zaire EBola Research Alliance group
  • Lancet Infect Dis. 20(6):707-718
  • 2020-06-01

• Field evaluation of a Pan-Lassa rapid diagnostic test during the 2018 Nigerian Lassa fever outbreak

  • Boisen ML, Uyigue E, Aiyepada J, Siddle KJ, Oestereich L, Nelson DKS, Bush DJ, Rowland MM, Heinrich ML, Eromon P, Kayode AT, Odia I, Adomeh DI, Muoebonam EB, Akhilomen P, Okonofua G, Osiemi B, Omoregie O, Airende M, Agbukor J, Ehikhametalor S, Aire CO, Duraffour S, Pahlmann M, Böhm W, Barnes KG, Mehta S, Momoh M, Sandi JD, Goba A, Folarin OA, Ogbaini-Emovan E, Asogun DA, Tobin EA, Akpede GO, Okogbenin SA, Okokhere PO, Grant DS, Schieffelin JS, Sabeti PC, Günther S, Happi CT, Branco LM, Garry RF.
  • Sci Rep. 10(1):8724
  • 2020-05-26

• Structural insights into reptarenavirus cap-snatching machinery

  • Rosenthal M, Gogrefe N, Vogel D, Reguera J, Rauschenberger B, Cusack S, Günther S, Reindl S
  • PLoS Pathog. 13(5):e1006400
  • 2017-05-15

• Relapsing cutaneous leishmaniasis in a patient requiring TNF-α-inhibitor Infliximab for Takayasu-arteritis: Case report and review of the literature.

  • Heinemann M, Omansen TF, Hennigs A, Völker K, Menz A, Addo MM, Schmiedel S.
  • Travel Med Infect Dis. 2020 Sep-Oct;37:101700. doi: 10.1016/j.tmaid.2020.101700. Epub 2020 Apr 25.
  • 2020-04-25

• 2018 Ebola virus disease outbreak in Équateur Province, Democratic Republic of the Congo: a retrospective genomic characterisation

  • Mbala-Kingebeni P, Pratt CB, Wiley MR, Diagne MM, Makiala-Mandanda S, Aziza A, Di Paola N, Chitty JA, Diop M, Ayouba A, Vidal N, Faye O, Faye O, Karhemere S, Aruna A, Nsio J, Mulangu F, Mukadi D, Mukadi P, Kombe J, Mulumba A, Duraffour S, Likofata J, Pukuta E, Caviness K, Bartlett ML, Gonzalez J, Minogue T, Sozhamannan S, Gross SM, Schroth GP, Kuhn JH, Donaldson EF, Delaporte E, Sanchez-Lockhart M, Peeters M, Muyembe-Tamfum JJ, Alpha Sall A, Palacios G, Ahuka-Mundeke S.
  • Lancet Infect Dis. 2019 Jun;19(6):641-647. doi: 10.1016/S1473-3099(19)30124-0. Epub 2019 Apr 15.
  • 2020-04-20

• Zikavirus prME Envelope Pseudotyped Human Immunodeficiency Virus Type-1 as a Novel Tool for Glioblastoma-Directed Virotherapy

  • Kretschmer M, Kadlubowska P, Hoffmann D, Schwalbe B, Auerswald H, Schreiber M. . :1000. doi: 10.3390/cancers12041000. PMID: 32325703; PMCID: PMC7226176.
  • Cancers (Basel). 12(4)
  • 2020-04-18

• Prospective observational study on the pharmacokinetic properties of the Irrua ribavirin regimen used in routine clinical practice in patients with Lassa fever in Nigeria

  • Erameh C, Edeawe O, Akhideno P, Eifediyi G, Omansen TF, Wagner C, Sarpong F, Koch T, Wicha S, Kurth F, Duraffour S, Oestereich L, Pahlmann M, Okogbenin S, Ogbaini-Emovon E, Günther S, Ramharter M, Groger M.
  • BMJ Open. 10(4):e036936
  • 2020-04-16

• West Nile Virus Epidemic in Germany Triggered by Epizootic Emergence, 2019

  • Ziegler U, Santos PD, Groschup MH, Hattendorf C, Eiden M, Höper D, Eisermann P, Keller M, Michel F, Klopfleisch R, Müller K, Werner D, Kampen H, Beer M, Frank C, Lachmann R, Tews BA, Wylezich C, Rinder M, Lachmann L, Grünewald T, Szentiks CA, Sieg M, Schmidt-Chanasit J, Cadar D, Lühken R
  • Viruses. 2020 Apr 15;12(4):448. doi: 10.3390/v12040448
  • 2020-04-15

• The Cap-Snatching Mechanism of Bunyaviruses

  • Olschewski S, Cusack S, Rosenthal M
  • Trends Microbiol. 28(4):293-303
  • 2020-04-01

• Density dependence and persistence of Morogoro arenavirus transmission in a fluctuating population of its reservoir host

  • Mariën J, Borremans B, Verhaeren C, Kirkpatrick L, Gryseels S, Goüy de Bellocq J, Günther S, Sabuni CA, Massawe AW, Reijniers J, Leirs H
  • J Anim Ecol. 89(2):506-518
  • 2020-02-01

• Acute Abdomen in Pediatric Patients With Lassa Fever: Prevalence and Response to Nonoperative Management

  • Akpede GO, Adetunji AE, Udefiagbon EO, Eluehike SO, Odike AI, Ewah-Odiase RO, Omosofe FO, Akerele JM, Atafo RO, Okonofua MO, Onyeke I, Oyedeji OA, Mbanefo K, Ogbaini-Emovon E, Okokhere PO, Günther S, Dongo AE
  • J Pediatric Infect Dis Soc. 8(6):519-524
  • 2019-12-27

• Lassa Fever: Epidemiology, Clinical Features, Diagnosis, Management and Prevention

  • Asogun DA, Günther S, Akpede GO, Ihekweazu C, Zumla A
  • Infect Dis Clin North Am. 33(4):933-951
  • 2019-12-01

• Tigray Orthohantavirus Infects Two Related Rodent Species Adapted to Different Elevations in Ethiopia

  • Meheretu Y, Stanley WT, Craig EW, Goüy de Bellocq J, Bryja J, Leirs H, Pahlmann M, Günther S.
  • Vector Borne Zoonotic Dis. 19(12):950-953
  • 2019-12-01

• Structure and function of the Toscana virus cap-snatching endonuclease.

  • Jones R, Lessoued S, Meier K, Devignot S, Barata-García S, Mate M, Bragagnolo G, Weber F, Rosenthal M, Reguera J.
  • Nucleic Acids Res. 2019 Oct 4. pii: gkz838. doi: 10.1093/nar/gkz838. [Epub ahead of print] PubMed PMID: 31584100.
  • 2019-10-04

• Lassa Virus in Pygmy Mice, Benin, 2016-2017

  • Yadouleton A, Agolinou A, Kourouma F, Saizonou R, Pahlmann M, Bedié SK, Bankolé H, Becker-Ziaja B, Gbaguidi F, Thielebein A, Magassouba N, Duraffour S, Baptiste JP, Günther S, Fichet-Calvet E
  • Emerg Infect Dis. 25(10):1977-1979
  • 2019-10-01

• Corrigendum: Caseload and Case Fatality of Lassa Fever in Nigeria, 2001-2018: A Specialist Center's Experience and Its Implications

  • Akpede GO, Asogun DA, Okogbenin SA, Dawodu SO, Momoh MO, Dongo AE, Ike C, Tobin E, Akpede N, Ogbaini-Emovon E, Adewale AE, Ochei O, Onyeke F, Okonofua MO, Atafo RO, Odia I, Adomeh DI, Odigie G, Ogbeifun C, Muoebonam E, Ihekweazu C, Ramharter M, Colubri A, Sabeti PC, Happi CT, Günther S, Agbonlahor DE
  • Front Public Health. 7:251
  • 2019-09-13

• Highly diversified shrew hepatitis B viruses corroborate ancient origins and divergent infection patterns of mammalian hepadnaviruses

  • Rasche A, Lehmann F, König A, Goldmann N, Corman VM, Moreira-Soto A, Geipel A, van Riel D, Vakulenko YA, Sander AL, Niekamp H, Kepper R, Schlegel M, Akoua-Koffi C, Souza BFCD, Sahr F, Olayemi A, Schulze V, Petraityte-Burneikiene R, Kazaks A, Lowjaga KAAT, Geyer J, Kuiken T, Drosten C, Lukashev AN, Fichet-Calvet E, Ulrich RG, Glebe D, Drexler JF
  • Proc Natl Acad Sci U S A. 116(34):17007-17012
  • 2019-08-20

• Phylogeography of Lassa Virus in Nigeria

  • Ehichioya DU, Dellicour S, Pahlmann M, Rieger T, Oestereich L, Becker-Ziaja B, Cadar D, Ighodalo Y, Olokor T, Omomoh E, Oyakhilome J, Omiunu R, Agbukor J, Ebo B, Aiyepada J, Ebhodaghe P, Osiemi B, Ehikhametalor S, Akhilomen P, Airende M, Esumeh R, Muoebonam E, Giwa R, Ekanem A, Igenegbale G, Odigie G, Okonofua G, Enigbe R, Omonegho Yerumoh E, Pallasch E, Bockholt S, Kafetzopoulou LE, Duraffour S, Okokhere PO, Akpede GO, Okogbenin SA, Odia I, Aire C, Akpede N, Tobin E, Ogbaini-Emovon E, Lemey P, Adomeh DI, Asogun DA, Günther S.
  • J Virol. 2019 Oct 15;93(21):e00929-19. doi: 10.1128/JVI.00929-19. Print 2019 Nov 1.
  • 2019-08-16

• Retrospective Cohort Study of Lassa Fever in Pregnancy, Southern Nigeria

  • Okogbenin S, Okoeguale J, Akpede G, Colubri A, Barnes KG, Mehta S, Eifediyi R, Okogbo F, Eigbefoh J, Momoh M, Rafiu M, Adomeh D, Odia I, Aire C, Atafo R, Okonofua M, Pahlman M, Becker-Ziaja B, Asogun D, Okokhere P, Happi C, Günther S, Sabeti PC, Ogbaini-Emovon E.
  • Emerg Infect Dis. 25(8):1494–500
  • 2019-08-01

• Caseload and Case Fatality of Lassa Fever in Nigeria, 2001-2018: A Specialist Center's Experience and Its Implications

  • Akpede GO, Asogun DA, Okogbenin SA, Dawodu SO, Momoh MO, Dongo AE, Ike C, Tobin E, Akpede N, Ogbaini-Emovon E, Adewale AE, Ochei O, Onyeke F, Okonofua MO, Atafo RO, Odia I, Adomeh DI, Odigie G, Ogbeifun C, Muebonam E, Ihekweazu C, Ramharter M, Colubri A, Sarbeti PC, Happi CT, Günther S, Agbonlahor DE
  • Front Public Health. 7:170
  • 2019-06-25

• Rift Valley fever virus minigenome system for investigating the role of L protein residues in viral transcription and replication.

  • Jérôme H, Rudolf M, Lelke M, Pahlmann M, Busch C, Bockholt S, Wurr S, Günther S, Rosenthal M, Kerber R.
  • J Gen Virol. 2019 Jun 6. doi: 10.1099/jgv.0.001281.
  • 2019-06-06

• Structure of a functional cap-binding domain in Rift Valley fever virus L protein.

  • Gogrefe N, Reindl S, Günther S, Rosenthal M.
  • PLoS Pathog. 2019 May 28;15(5):e1007829. doi: 10.1371/journal.ppat.1007829.
  • 2019-05-28

• Lymphocytic choriomeningitis virus meningitis after needlestick injury: a case report

  • Dräger S, Marx AF, Pigny F, Cherpillod P, Eisermann P, Sendi P, Widmer AF
  • Antimicrob Resist Infect Control. 8:77
  • 2019-05-20

• Biochemical characterization of the Lassa virus L protein.

  • Vogel D, Rosenthal M, Gogrefe N, Reindl S, Günther S.
  • J Biol Chem. 2019 Mar 29. pii: jbc.RA118.006973. doi: 10.1074/jbc.RA118.006973. [Epub ahead of print]
  • 2019-03-29

• The Dengue ED3 Dot Assay, a Novel Serological Test for the Detection of Denguevirus Type-Specific Antibodies and Its Application in a Retrospective Seroprevalence Study

  • Auerswald H, Klepsch L, Schreiber S, Hülsemann J, Franzke K, Kann S, Y B, Duong V, Buchy P, Schreiber M
  • Viruses. 11(4):304
  • 2019-03-27

• Ebola virus disease

  • Malvy D, McElroy AK, de Clerck H, Günther S, van Griensven J
  • Lancet. 393(10174):936-948
  • 2019-03-02

• Laboratory Findings, Compassionate Use of Favipiravir, and Outcome in Patients With Ebola Virus Disease, Guinea, 2015-A Retrospective Observational Study

  • Kerber R, Lorenz E, Duraffour S, Sissoko D, Rudolf M, Jaeger A, Cisse SD, Camara AM, Miranda O, Castro CM, Akoi Bore J, Raymond Koundouno F, Repits J, Afrough B, Becker-Ziaja B, Hinzmann J, Mertens M, Vitoriano I, Hugh Logue C, Böttcher JP, Pallasch E, Sachse A, Bah A, Cabeza-Cabrerizo M, Nitzsche K, Kuisma E, Michel J, Holm T, Zekeng EG, Cowley LA, Garcia-Dorival I, Hetzelt N, Baum JHJ, Portmann J, Carter L, Yenamaberhan RL, Camino A, Enkirch T, Singethan K, Meisel S, Mazzarelli A, Kosgei A, Kafetzopoulou L, Rickett NY, Patrono LV, Ghebreghiorghis L, Arnold U, Colin G, Juchet S, Marchal CL, Kolie JS, Beavogui AH, Wurr S, Bockholt S, Krumkamp R, May J, Stoecker K, Fleischmann E, Ippolito G, Carroll MW, Koivogui L, Magassouba N, Keita S, Gurry C, Drury P, Diallo B, Formenty P, Wölfel R, Di Caro A, Gabriel M, Anglaret X, Malvy D, Günther S.
  • J Infect Dis. 2019 Jun 19;220(2):195-202. doi: 10.1093/infdis/jiz078.
  • 2019-02-22

• Crimean-Congo Hemorrhagic Fever, Kosovo, 2013-2016

  • Ahmeti S, Berisha L, Halili B, Ahmeti F, von Possel R, Thomé-Bolduan C, Michel A, Priesnitz S, Reisinger EC, Günther S, Krüger A, Sherifi K, Jakupi X, Hemmer CJ, Emmerich P
  • Emerg Infect Dis. 25(2):321-324
  • 2019-02-01

• Metagenomic sequencing at the epicenter of the Nigeria 2018 Lassa fever outbreak

  • Kafetzopoulou LE, Pullan ST, Lemey P, Suchard MA, Ehichioya DU, Pahlmann M, Thielebein A, Hinzmann J, Oestereich L, Wozniak DM, Efthymiadis K, Schachten D, Koenig F, Matjeschk J, Lorenzen S, Lumley S, Ighodalo Y, Adomeh DI, Olokor T, Omomoh E, Omiunu R, Agbukor J, Ebo B, Aiyepada J, Ebhodaghe P, Osiemi B, Ehikhametalor S, Akhilomen P, Airende M, Esumeh R, Muoebonam E, Giwa R, Ekanem A, Igenegbale G, Odigie G, Okonofua G, Enigbe R, Oyakhilome J, Yerumoh EO, Odia I, Aire C, Okonofua M, Atafo R, Tobin E, Asogun D, Akpede N, Okokhere PO, Rafiu MO, Iraoyah KO, Iruolagbe CO, Akhideno P, Erameh C, Akpede G, Isibor E, Naidoo D, Hewson R, Hiscox JA, Vipond R, Carroll MW, Ihekweazu C, Formenty P, Okogbenin S, Ogbaini-Emovon E, Günther S, Duraffour S
  • Science. 363(6422):74-77
  • 2019-01-04

• T-Cell Receptor Diversity and the Control of T-Cell Homeostasis Mark Ebola Virus Disease Survival in Humans

  • Speranza E, Ruibal P, Port JR, Feng F, Burkhardt L, Grundhoff A, Günther S, Oestereich L, Hiscox JA, Connor JH, Muñoz-Fontela C
  • J Infect Dis. 2018 Nov 22;218(suppl_5):S508-S518. doi: 10.1093/infdis/jiy352
  • 2018-11-22

• Immunogenicity of a novel tetravalent dengue envelope protein domain III-based antigen in mice

  • Fahimi H, Sadeghizadeh M, Hassan ZM, Auerswald H, Schreiber M
  • EXCLI J. 17:1054-1068
  • 2018-11-05

• Mücken und Zecken als Krankheitsvektoren: der Einfluss der Klimaerwärmung [Mosquitoes and Ticks: The Influence of Global Warming in the Transmission of Infectious Diseases in Germany]

  • Hemmer CJ, Emmerich P, Loebermann M, Frimmel S, Reisinger EC
  • Dtsch Med Wochenschr. 143(23):1714-1722
  • 2018-11-01

• Biochemical and structural studies reveal differences and commonalities among cap-snatching endonucleases from segmented negative-strand RNA viruses.

  • Holm T, Kopicki JD, Busch C, Olschewski S, Rosenthal M, Uetrecht C, Günther S, Reindl S.
  • J Biol Chem. 2018 Oct 22. pii: jbc.RA118.004373. doi: 10.1074/jbc.RA118.004373.
  • 2018-10-22

• Role of the C Terminus of Lassa Virus L Protein in Viral mRNA Synthesis.

  • Lehmann M, Pahlmann M, Jerome H, Busch C, Lelke M, Günther S.
  • J Virol. 2014 Aug;88(15):8713-7. doi: 10.1128/JVI.00652-14.
  • 2018-08-15

• Kinetics of Soluble Mediators of the Host Response in Ebola Virus Disease

  • Kerber R, Krumkamp R, Korva M, Rieger T, Wurr S, Duraffour S, Oestereich L, Gabriel M, Sissoko D, Anglaret X, Malvy D, May J, Županc TA, Muñoz-Fontela C, Günther S.
  • J Infect Dis. 2018 Nov 22;218(suppl_5):S496-S503. doi: 10.1093/infdis/jiy429.
  • 2018-08-14

• Widespread arenavirus occurrence and seroprevalence in small mammals, Nigeria

  • Olayemi A, Oyeyiola A, Obadare A, Igbokwe J, Adesina AS, Onwe F, Ukwaja KN, Ajayi NA, Rieger T, Günther S, Fichet-Calvet E.
  • Parasit Vectors. 11(1):416
  • 2018-07-13

• Acute Lassa Virus Encephalitis with Lassa Virus in the Cerebrospinal Fluid but Absent in the Blood: A Case Report with a Positive Outcome

  • Okokhere PO, Erameh CO, Alikah F, Akhideno PE, Iruolagbe CO, Osazuwa OO, Bankole IA, Adomeh DI, Odia I, Aire CO, Oyakhilome J, Agbukor J, Atafo RO, Asogun DA, Happi CT, Sabeti PC, Günther S, Akpede GO
  • Case Rep Neurol. 10(2):150-158
  • 2018-07-03

• Clinical and laboratory predictors of Lassa fever outcome in a dedicated treatment facility in Nigeria: a retrospective, observational cohort study

  • Okokhere P, Colubri A, Azubike C, Iruolagbe C, Osazuwa O, Tabrizi S, Chin E, Asad S, Ediale E, Rafiu M, Adomeh D, Odia I, Atafo R, Aire C, Okogbenin S, Pahlman M, Becker-Ziaja B, Asogun D, Fradet T, Fry B, Schaffner SF, Happi C, Akpede G, Günther S, Sabeti PC
  • Lancet Infect Dis. 18(6):684-695
  • 2018-06-01

• Antibodies to the Glycoprotein GP2 Subunit Cross-React between Old and New World Arenaviruses

  • Amanat F, Duehr J, Oestereich L, Hastie KM, Ollmann Saphire E, Krammer F
  • mSphere. 3(3):e00189-18
  • 2018-05-02

• A one-step multiplex real-time RT-PCR for the universal detection of all currently known CCHFV genotypes

  • Sas MA, Vina-Rodriguez A, Mertens M, Eiden M, Emmerich P, Chaintoutis SC, Mirazimi A, Groschup MH
  • J Virol Methods. 255:38-43
  • 2018-05-01

• Development and evaluation of antibody-capture immunoassays for detection of Lassa virus nucleoprotein-specific immunoglobulin M and G

  • Gabriel M, Adomeh DI, Ehimuan J, Oyakhilome J, Omomoh EO, Ighodalo Y, Olokor T, Bonney K, Pahlmann M, Emmerich P, Lelke M, Brunotte L, Ölschläger S, Thomé-Bolduan C, Becker-Ziaja B, Busch C, Odia I, Ogbaini-Emovon E, Okokhere PO, Okogbenin SA, Akpede GO, Schmitz H, Asogun DA, Günther S.
  • PLoS Negl Trop Dis. 12(3)
  • 2018-03-29

• Field investigation with real-time virus genetic characterisation support of a cluster of Ebola virus disease cases in Dubréka, Guinea, April to June 2015

  • Pini A, Zomahoun D, Duraffour S, Derrough T, Charles M, Quick J, Loman N, Cowley L, Leno M, Ouedraogo N, Thiam O, Hernández-Romieu A, Iko A, Keita H, Konate D, Soumah AA, Bouchouar E, Ileka-Priouzeau S, Keita S, Diallo B, Cisse F, Jansa J, Carroll M, Günther S, Severi E, Formenty P.
  • Euro Surveill. 2018 Mar;23(12):17-00140. doi: 10.2807/1560-7917.ES.2018.23.12.17-00140.
  • 2018-03-29

• Antiviral efficacy of favipiravir against Ebola virus: A translational study in cynomolgus macaques

  • Guedj J, Piorkowski G, Jacquot F, Madelain V, Nguyen THT, Rodallec A, Gunther S, Carbonnelle C, Mentré F, Raoul H, de Lamballerie X
  • PLoS Med. 15(3):e1002535
  • 2018-03-27

• Arenavirus infection correlates with lower survival of its natural rodent host in a long-term capture-mark-recapture study

  • Mariën J, Sluydts V, Borremans B, Gryseels S, Vanden Broecke B, Sabuni CA, Katakweba AAS, Mulungu LS, Günther S, de Bellocq JG, Massawe AW, Leirs H
  • Parasit Vectors. 11(1):90
  • 2018-02-08

• Erratum for Madelain et al., "Favipiravir Pharmacokinetics in Nonhuman Primates and Insights for Future Efficacy Studies of Hemorrhagic Fever Viruses"

  • Madelain V, Guedj J, Mentré F, Nguyen THT, Jacquot F, Oestereich L, Kadota T, Yamada K, Taburet AM, de Lamballerie X, Raoul H
  • Antimicrob Agents Chemother. 2017 Dec 21;62(1). pii: e02093-17. doi: 10.1128/AAC.02093-17. Print 2018 Jan
  • 2017-12-21

• Expression and purification of the surface proteins from Andes virus.

  • Beltrán-Ortiz CE, Starck-Mendez MF, Fernández Y, Farnós O, González EE, Rivas CI, Camacho F, Zuñiga FA, Toledo JR, Sánchez O.
  • Protein Expression and Purification. 139: 63-70. doi:10.1016/j.pep.2015.09.013.
  • 2017-07-27

• Determining Ribavirin's mechanism of action against Lassa virus infection

  • Carrillo-Bustamante P, Nguyen THT, Oestereich L, Günther S, Guedj J, Graw F
  • Sci Rep. 2017 Sep 15;7(1):11693. doi: 10.1038/s41598-017-10198-0
  • 2017-09-15

• Deep Sequencing of RNA from Blood and Oral Swab Samples Reveals the Presence of Nucleic Acid from a Number of Pathogens in Patients with Acute Ebola Virus Disease and Is Consistent with Bacterial Translocation across the Gut

  • Carroll MW, Haldenby S, Rickett NY, Pályi B, Garcia-Dorival I, Liu X, Barker G, Bore JA, Koundouno FR, Williamson ED, Laws TR, Kerber R, Sissoko D, Magyar N, Di Caro A, Biava M, Fletcher TE, Sprecher A, Ng LFP, Rénia L, Magassouba N, Günther S, Wölfel R, Stoecker K, Matthews DA, Hiscox JA
  • mSphere. 2(4):e00325-17
  • 2017-08-23

• Schwere Gelbfieber-impfassoziierte Erkrankung: ein Fallbericht und aktuelle Übersicht [Severe Yellow fever vaccine-associated disease: a case report and current overview]

  • Slesak G, Gabriel M, Domingo C, Schäfer J
  • Dtsch Med Wochenschr. 142(16):1219-1222. German.
  • 2017-08-01

• Novel Cross-Reactive Monoclonal Antibodies against Ebolavirus Glycoproteins Show Protection in a Murine Challenge Model

  • Duehr J, Wohlbold TJ, Oestereich L, Chromikova V, Amanat F, Rajendran M, Gomez-Medina S, Mena I, tenOever BR, García-Sastre A, Basler CF, Munoz-Fontela C, Krammer F
  • J Virol. 2017 Jul 27;91(16). pii: e00652-17. doi: 10.1128/JVI.00652-17. Print 2017 Aug 15
  • 2017-07-27

• Autochthonous Crimean-Congo Hemorrhagic Fever in Spain

  • Negredo A, de la Calle-Prieto F, Palencia-Herrejón E, Mora-Rillo M, Astray-Mochales J, Sánchez-Seco MP, Bermejo Lopez E, Menárguez J, Fernández-Cruz A, Sánchez-Artola B, Keough-Delgado E, Ramírez de Arellano E, Lasala F, Milla J, Fraile JL, Ordobás Gavín M, Martinez de la Gándara A, López Perez L, Diaz-Diaz D, López-García MA, Delgado-Jimenez P, Martín-Quirós A, Trigo E, Figueira JC, Manzanares J, Rodriguez-Baena E, Garcia-Comas L, Rodríguez-Fraga O, García-Arenzana N, Fernández-Díaz MV, Cornejo VM, Emmerich P, Schmidt-Chanasit J, Arribas JR; Crimean Congo Hemorrhagic Fever@Madrid Working Group
  • N Engl J Med. 377(2):154-161
  • 2017-07-13

• Prevalence of Lassa Virus Disease (LVD) in Nigerian children with fever or fever and convulsions in an endemic area

  • Akhuemokhan OC, Ewah-Odiase RO, Akpede N, Ehimuan J, Adomeh DI, Odia I, Olomu SC, Pahlmann M, Becker-Ziaja B, Happi CT, Asogun DA, Okogbenin SA, Okokhere PO, Dawodu OS, Omoike IU, Sabeti PC, Günther S, Akpede GO . doi: 10.1371/journal.pntd.0005711. PMID: 28671959; PMCID: PMC5510890.
  • PLoS Negl Trop Dis. 11(7):e0005711
  • 2017-07-03

• Different features of Vδ2 T and NK cells in fatal and non-fatal human Ebola infections

  • Cimini E, Viola D, Cabeza-Cabrerizo M, Romanelli A, Tumino N, Sacchi A, Bordoni V, Casetti R, Turchi F, Martini F, Bore JA, Koundouno FR, Duraffour S, Michel J, Holm T, Zekeng EG, Cowley L, Garcia Dorival I, Doerrbecker J, Hetzelt N, Baum JHJ, Portmann J, Wölfel R, Gabriel M, Miranda O, Díaz G, Díaz JE, Fleites YA, Piñeiro CA, Castro CM, Koivogui L, Magassouba N, Diallo B, Ruibal P, Oestereich L, Wozniak DM, Lüdtke A, Becker-Ziaja B, Capobianchi MR, Ippolito G, Carroll MW, Günther S, Di Caro A, Muñoz-Fontela C, Agrati C
  • PLoS Negl Trop Dis. 2017 May 30;11(5):e0005645. doi: 10.1371/journal.pntd.0005645. eCollection 2017 May
  • 2017-05-30

• Structural insights into reptarenavirus cap-snatching machinery

  • Rosenthal M, Gogrefe N, Vogel D, Reguera J, Rauschenberger B, Cusack S, Günther S, Reindl S
  • PLoS Pathog. 13(5):e1006400
  • 2017-05-15

• External quality assessment study for ebolavirus PCR-diagnostic promotes international preparedness during the 2014 - 2016 Ebola outbreak in West Africa

  • Ellerbrok H, Jacobsen S, Patel P, Rieger T, Eickmann M, Becker S, Günther S, Naidoo D, Schrick L, Keeren K, Targosz A, Teichmann A, Formenty P, Niedrig M
  • PLoS Negl Trop Dis. 11(5):e0005570
  • 2017-05-01

• No measurable adverse effects of Lassa, Morogoro and Gairo arenaviruses on their rodent reservoir host in natural conditions

  • Mariën J, Borremans B, Gryseels S, Soropogui B, De Bruyn L, Bongo GN, Becker-Ziaja B, de Bellocq JG, Günther S, Magassouba N, Leirs H, Fichet-Calvet E. . . doi: 10.1186/s13071-017-2146-0. PMID: 28449693; PMCID: PMC5408478.
  • Parasit Vectors. 10(1):210
  • 2017-04-27

• How to treat Ebola virus infections? A lesson from the field

  • Duraffour S, Malvy D, Sissoko D.
  • Curr Opin Virol. 2017 Jun;24:9-15. doi: 10.1016/j.coviro.2017.03.003. Epub 2017 Apr 11.
  • 2017-04-15

• Virus genomes reveal factors that spread and sustained the Ebola epidemic

  • Dudas G, Carvalho LM, Bedford T, Tatem AJ, Baele G, Faria NR, Park DJ, Ladner JT, Arias A, Asogun D, Bielejec F, Caddy SL, Cotten M, D'Ambrozio J, Dellicour S, Di Caro A, Diclaro JW, Duraffour S, Elmore MJ, Fakoli LS, Faye O, Gilbert ML, Gevao SM, Gire S, Gladden-Young A, Gnirke A, Goba A, Grant DS, Haagmans BL, Hiscox JA, Jah U, Kugelman JR, Liu D, Lu J, Malboeuf CM, Mate S, Matthews DA, Matranga CB, Meredith LW, Qu J, Quick J, Pas SD, Phan MVT, Pollakis G, Reusken CB, Sanchez-Lockhart M, Schaffner SF, Schieffelin JS, Sealfon RS, Simon-Loriere E, Smits SL, Stoecker K, Thorne L, Tobin EA, Vandi MA, Watson SJ, West K, Whitmer S, Wiley MR, Winnicki SM, Wohl S, Wölfel R, Yozwiak NL, Andersen KG, Blyden SO, Bolay F, Carroll MW, Dahn B, Diallo B, Formenty P, Fraser C, Gao GF, Garry RF, Goodfellow I, Günther S, Happi CT, Holmes EC, Kargbo B, Keïta S, Kellam P, Koopmans MPG, Kuhn JH, Loman NJ, Magassouba N, Naidoo D, Nichol ST, Nyenswah T, Palacios G, Pybus OG, Sabeti PC, Sall A, Ströher U, Wurie I, Suchard MA, Lemey P, Rambaut A.
  • Nature. 2017 Apr 20;544(7650):309-315. doi: 10.1038/nature22040. Epub 2017 Apr 12.
  • 2017-04-14

• Interferon β-1a for the treatment of Ebola virus disease: A historically controlled, single-arm proof-of-concept trial

  • Konde MK, Baker DP, Traore FA, Sow MS, Camara A, Barry AA, Mara D, Barry A, Cone M, Kaba I, Richard AA, Beavogui AH, Günther S; European Mobile Laboratory Consortium; Pintilie M, Fish EN
  • PLoS One. 12(2):e0169255
  • 2017-02-22

• Transcriptomic signatures differentiate survival from fatal outcomes in humans infected with Ebola virus

  • Liu X, Speranza E, Muñoz-Fontela C, Haldenby S, Rickett NY, Garcia-Dorival I, Fang Y, Hall Y, Zekeng EG, Lüdtke A, Xia D, Kerber R, Krumkamp R, Duraffour S, Sissoko D, Kenny J, Rockliffe N, Williamson ED, Laws TR, N'Faly M, Matthews DA, Günther S, Cossins AR, Sprecher A, Connor JH, Carroll MW, Hiscox JA.
  • Genome Biol. 2017 Jan 19;18(1):4. doi: 10.1186/s13059-016-1137-3.
  • 2017-01-20

• Ebola virus infection kinetics in chimeric mice reveal a key role of T cells as barriers for virus dissemination

  • Lüdtke A, Ruibal P, Wozniak DM, Pallasch E, Wurr S, Bockholt S, Gómez-Medina S, Qiu X, Kobinger GP, Rodríguez E, Günther S, Krasemann S, Idoyaga J, Oestereich L, Muñoz-Fontela C
  • TBA
  • 2017-01-10

• Ebola Virus Persistence in Breast Milk After No Reported Illness: A Likely Source of Virus Transmission From Mother to Child

  • Sissoko D, Keïta M, Diallo B, Aliabadi N, Fitter DL, Dahl BA, Akoi Bore J, Raymond Koundouno F, Singethan K, Meisel S, Enkirch T, Mazzarelli A, Amburgey V, Faye O, Alpha Sall A, Magassouba N, Carroll MW, Anglaret X, Malvy D, Formenty P, Bruce Aylward R, Keïta S, Harouna Djingarey M, Loman NJ, Günther S, Duraffour S.
  • Clin Infect Dis. 2017 Feb 15;64(4):513-516. doi: 10.1093/cid/ciw793.
  • 2017-01-07

• Persistence and clearance of Ebola virus RNA from seminal fluid of Ebola virus disease survivors: a longitudinal analysis and modelling study

  • Sissoko D, Duraffour S, Kerber R, Kolie JS, Beavogui AH, Camara AM, Colin G, Rieger T, Oestereich L, Pályi B, Wurr S, Guedj J, Nguyen THT, Eggo RM, Watson CH, Edmunds WJ, Bore JA, Koundouno FR, Cabeza-Cabrerizo M, Carter LL, Kafetzopoulou LE, Kuisma E, Michel J, Patrono LV, Rickett NY, Singethan K, Rudolf M, Lander A, Pallasch E, Bockholt S, Rodríguez E, Di Caro A, Wölfel R, Gabriel M, Gurry C, Formenty P, Keïta S, Malvy D, Carroll MW, Anglaret X, Günther S
  • Lancet Glob Health. 2017 Jan;5(1):e80-e88. doi: 10.1016/S2214-109X(16)30243-1
  • 2017-01-05