Our publications
2022
Pharmacokinetics of ribavirin in the treatment of Lassa fever: An observational clinical study at the Irrua Specialist Teaching Hospital, Edo State, Nigeria
- Mirjam Groger, Peter Akhideno, Christine J Kleist, Femi O Babatunde, Osahogie Edeawe, Julia Hinzmann, ThankGod Akhigbe, Joy Nwatuzor, Gloria Eifediyi, Jonas Müller, Mette Hinrichs, Meike Pahlmann, Francisca Naana Sarpong, Christine Wagner, Anke Thielebein, Louis Aihonwalan, Till Koch, Maria Riedner, Ephraim Ogbaini-Emovon, Sylvanus Okogbenin, Stephan Günther, Sebastian G Wicha, Michael Ramharter, Lisa Oestereich, Sophie Duraffour, Cyril Erameh
- Clin Infect Dis. ciac578:online
Effectiveness of pyronaridine-artesunate against Plasmodium malariae, Plasmodium ovale spp, and mixed-Plasmodium infections: a post-hoc analysis of the CANTAM-Pyramax trial.
- Mirjam Groger, Gaston Tona Lutete, Ghyslain Mombo-Ngoma, Nsengi Y Ntamabyaliro, Gauthier Kahunu Mesia, Trésor Bodjick Muena Mujobu, Lia Betty Dimessa Mbadinga, Rella Zoleko Manego, Diane Egger-Adam, Isabelle Borghini-Fuhrer, Jangsik Shin, Robert Miller, Sarah Arbe-Barnes, Stephan Duparc, Michael Ramharter
- The Lancet Microbe. online
Challenges in the clinical development pathway for triple and multiple drug combinations in the treatment of uncomplicated falciparum malaria.
- Quique Bassat, Oumou Maïga-Ascofaré, Jürgen May, Jerôme Clain, Ghyslain Mombo-Ngoma, Mirjam Groger, Ayôla A. Adegnika, Jean-Claude Dejon Agobé, Abdoulaye Djimde, Johannes Mischlinger, Michael Ramharter on behalf of ASAAP and Multimal Consortia
- Malaria Journal. 21:61.
2021
Diagnostic performance of capillary and venous blood samples in the detection of Loa loa and Mansonella perstans microfilaraemia using light microscopy.
- Johannes Mischlinger, Rella Zoleko Manego, Ghyslain Mombo-Ngoma, Dorothea Ekoka Mbassi, Nina Hackbarth, Franck-Aurelien Ekoka Mbassi, Saskia Dede Davi, Ruth Kreuzmair, Luzia Veletzky, Jennifer Hergeth, Wilfrid Nzebe Ndoumba, Paul Pitzinger, Mirjam Groger, Pierre Blaise Matsiegui, Ayola Akim Adegnika, Selidji Todagbe Agnandji, Bertrand Lell, Michael Ramharter
- PLOS Neglected Tropical Diseases. 15(8): e0009623
Pyronaridine-artesunate real-world safety, tolerability, and effectiveness in malaria patients in 5 African countries: A single-arm, open-label, cohort event monitoring study.
- Gaston Tona Lutete, Ghyslain Mombo-Ngoma, Serge-Brice Assi, Jude D. Bigoga, Felix Koukouikila-Koussounda, Nsengi Y. Ntamabyaliro, Francine Ntoumi, Selidji T. Agnandji, Mirjam Groger, Jangsik Shin, Isabelle Borghini-Fuhrer, Sarah Arbe-Barnes, Stephen J. Allen, Peter G. Kremsner, Robert Miller, Stephan Duparc, Michael Ramharter, the CANTAM study group
- PLOS Medicine. 18(6):e1003669
2020
Prospective observational study on the pharmacokinetic properties of the Irrua ribavirin regimen used in routine clinical practice in patients with Lassa fever in Nigeria.
- Cyril Erameh, Osahogie Edeawe, Peter Akhideno, Gloria Eifediyi, Till F Omansen, Christine Wagner, Francisca Sarpong, Till Koch, Sebastian Wicha, Florian Kurth, Sophie Duraffour, Lisa Oestereich, Meike Pahlmann, Sylvanus Okogbenin, Ephraim Ogbaini-Emovon, Stephan Günther, Michael Ramharter, Mirjam Groger
- BMJ open. 10(4):e036936
2019
Reply to Lin et al.
- Groger M, Ramharter M
- Clinical Infectious Diseases. 70(9):2019–2020
Ribavirin for the treatment of Lassa fever: A systematic review and meta-analysis.
- Kirsten Alexandra Eberhardt, Johannes Mischlinger, Sabine Jordan, Mirjam Groger, Stephan Günther, Michael Ramharter
- International Journal of Infectious Diseases. 87 (2019) 15–20
Prospective clinical and molecular evaluation of potential plasmodium ovale curtisi and wallikeri relapses in a high-transmission setting.
- Mirjam Groger, Luzia Veletzky, Albert Lalremruata, Chiara Cattaneo, Johannes Mischlinger, Rella Manego Zoleko, Johanna Kim, Anna Klicpera, Elias L. Meyer, Daniel Blessborn, Markus Winterberg, Ayola A. Adegnika, Selidji T. Agnandji, Peter G. Kremsner, Benjamin Mordmüller, Ghyslain Mombo-Ngoma, Hans-Peter Fuehrer, and Michael Ramharter
- Clinical Infectious Diseases. 69(12):2119–26
FDG-PET/MRI imaging for the management of alveolar echinococcosis: initial clinical experience at a reference centre in Austria.
- Felix Lötsch, Fredrik Waneck, Mirjam Groger, Herbert Auer, Klaus Kaczirek, Ivo Rausch, Wolfgang Wadsak, Marcus Hacker, Heimo Lagler, Michael Ramharter, Georgios Karanikas
- Tropical Medicine & International Health. 24(6):336-670.
2018
Validity and reliability of methods to microscopically detect and quantify malaria parasitaemia.
- Johannes Mischlinger, Paul Pitzinger, Luzia Veletzky, Mirjam Groger, Rella Zoleko-Manego, Ayola A. Adegnika, Selidji T. Agnandji, Bertrand Lell, Peter G. Kremsner, Ghyslain Mombo-Ngoma, Benjamin Mordmüller, Michael Ramharter
- Tropical Medicine & International Health. 23(9):980-991
Preliminary Evidence for the Absence of Cystic Echinococcosis in Gabon: A Cross-Sectional Pilot Survey in Humans and Definitive Hosts.
- Felix Lötsch, Ghyslain Mombo-Ngoma, Johannes Mischlinger, Mirjam Groger, Luzia Veletzky, Ayôla Akim Adegnika, Bertrand Lell, Selidji Todagbe Agnandji, Marielle Bouyou-Akotet, Markus Obermüller, Marion Wassermann, Renate Schneider, Herbert Auer, Michael Ramharter
- The American Journal of Tropical Medicine and Hygiene. 99(1):97-101
Use of Capillary Blood Samples Leads to Higher Parasitemia Estimates and Higher Diagnostic Sensitivity of Microscopic and Molecular Diagnostics of Malaria than Venous Blood Samples.
- Johannes Mischlinger, Paul Pitzinger, Luzia Veletzky, Mirjam Groger, Rella Zoleko-Manego, Ayola A Adegnika, Selidji T Agnandji, Bertrand Lell, Peter G Kremsner, Egbert Tannich, Ghyslain Mombo-Ngoma, Benjamin Mordmüller, Michael Ramharter
- The Journal of Infectious Diseases. 2018(8):1296-1305
Detection of the Malaria causing Plasmodium Parasite in Saliva from Infected Patients using Topoisomerase I Activity as a Biomarker.
- Marianne Smedegaard Hede, Søren Fjelstrup, Felix Lötsch, Rella Manego Zoleko, Anna Klicpera, Mirjam Groger, Johannes Mischlinger, Lilian Endame, Luzia Veletzky, Ronja Neher, Anne Katrine Wrist Simonsen, Eskild Petersen, Ghyslain Mombo-Ngoma, Magnus Stougaard, Yi-Ping Ho, Rodrigo Labouriau, Michael Ramharter, Birgitta Ruth Knudsen
- Scientific Reports. 8:4122
Prospective Clinical Trial Assessing Species-Specific Efficacy of Artemether-Lumefantrine for the Treatment of Plasmodium malariae, Plasmodium ovale, and Mixed Plasmodium Malaria in Gabon.
- Mirjam Groger, Luzia Veletzky, Albert Lalremruata, Chiara Cattaneo, Johannes Mischlinger, Rella Zoleko-Manego, Lilian Endamne, Show All (19 Authors), Anna Klicpera, Johanna Kim, The Nguyen, Lena Flohr, Jonathan Remppis, Pierre-Blaise Matsiegui, Ayôla A. Adegnika, Selidji T. Agnandji, Peter G. Kremsner, Benjamin Mordmüller, Ghyslain Mombo-Ngoma, Michael Ramharter
- Antimicrobial Agents and Chemotherapy. 62(3):e01758-17
Molecular evidence for relapse of an imported Plasmodium ovale wallikeri infection.
- Luzia Veletzky, Mirjam Groger, Heimo Lagler, Julia Walochnik, Herbert Auer, Hans-Peter Fuehrer, Michael Ramharter
- Malaria Journal. 17:78
2017
Efficacy and safety of fosmidomycin-piperaquine as non-artemisinin-based combination therapy for uncomplicated falciparum malaria - A single-arm, age-de-escalation proof of concept study in Gabon.
- Ghyslain Mombo-Ngoma, Jonathan Remppis, Moritz Sievers, Rella Zoleko Manego, Lilian Endamne, Lumeka Kabwende, Luzia Veletzky, The Trong Nguyen, Mirjam Groger, Felix Lötsch, Johannes Mischlinger, Lena Flohr, Johanna Kim, Chiara Cattaneo, David Hutchinson, Stephan Duparc, Joerg Moehrle, Thirumalaisamy P Velavan, Bertrand Lell, Michael Ramharter, Ayola Akim Adegnika, Benjamin Mordmüller, Peter G Kremsner
- Clinical Infectious Diseases. 66(12):1823-1830
A randomised, double-blind clinical phase II trial of the efficacy, safety, tolerability and pharmacokinetics of a single dose combination treatment with artefenomel and piperaquine in adults and children with uncomplicated Plasmodium falciparum malaria.
- Fiona Macintyre, Yeka Adoke, Alfred B. Tiono, Tran Thanh Duong, Ghyslain Mombo-Ngoma, Marielle Bouyou-Akotet, Halidou Tinto, Quique Bassat, Saadou Issifou, Marc Adamy, Helen Demarest, Stephan Duparc, Didier Leroy, Bart E. Laurijssens, Sophie Biguenet, Afizi Kibuuka, Antoinette Kitoto Tshefu, Melnick Smith, Chanelle Foster, Illse Leipoldt, Peter G. Kremsner, Bui Quang Phuc, Alphonse Ouedraogo & Michael Ramharter on behalf of the OZ-Piperaquine Study Group
- BMC Medicine. 15:181
A systematic review of the clinical presentation, treatment and relapse characteristics of human Plasmodium ovale malaria.
- Mirjam Groger, Hannah S. Fischer, Luzia Veletzky, Albert Lalremruata, Michael Ramharter
- Malaria Journal. 16:112
2016
Seroprevalence of Toxocara spp. in a rural population in Central African Gabon.
- Felix Lötsch, Markus Obermüller, Johannes Mischlinger, Ghyslain Mombo-Ngom, Mirjam Groger, Akim Ayola Adegnika, Selidji Todagbe Agnandji, Renate Schneider, Herbert Auer, Michael Ramharter
- Parasitology International. 65(6):623-634
Intra-cystic concentrations of albendazole-sulphoxide in human cystic echinococcosis: a systematic review and analysis of individual patient data.
- Felix Lötsch, Judith Naderer, Tomislava Skuhala, Mirjam Groger, Herbert Auer, Klaus Kaczirek, Fredrik Waneck, Michael Ramharter
- Parasitology Research. 115:2995-3001
Effect of mild medical hypothermia on in vitro growth of Plasmodium falciparum and the activity of anti-malarial drugs.
- Khalid Rehman, Ulrich Sauerzopf, Luzia Veletzky, Felix Lötsch, Mirjam Groger, Michael Ramharter
- Malaria Journal. 15:162
2015
Streptococcus agalactiae Serotype Distribution and Antimicrobial Susceptibility in Pregnant Women in Gabon, Central Africa.
- Sabine Belard, Nicole Toepfner, Mesküre Capan-Melser, Ghyslain Mombo-Ngoma, Rella Zoleko-Manego, Mirjam Groger, Pierre-Blaise Matsiegui, Selidji T. Agnandji, Ayôla A. Adegnika, Raquel González, Peter G. Kremsner, Clara Menendez, Michael Ramharter, Reinhard Berner
- Scientific Reports. 5:17281
Epidemiology of Human Herpes Virus 8 in Pregnant Women and their Newborns--A cross-sectional delivery survey in Central Gabon.
- Mesküre Capan-Melser, GhyslainMombo-Ngoma, Daisy Akerey-Diop, Arti Basra, Rella Manego-Zoleko, Heike Würbel, Felix Lötsch, Mirjam Groger, Michael Skoll, Julia Schwing, Ulla Schipulle, Pierre-Blaise Matsiegui, Raquel González, Clara Menendez, Peter G.Kremsner, Ayôla A.Adegnika, Selidji T. Agnandji, Michael Ramharter
- International Journal of Infectious Diseases. 39:16-19
Adherence of patients to long-term medication: a cross-sectional study of antihypertensive regimens in Austria.
- Felix Lötsch, Lorenz Auer-Hackenberg, Mirjam Groger, Khalid Rehman, Valerie Morrison, Emily Holmes, Sahdia Parveen, Catrin Plumpton, Wendy Clyne, Sabina de Geest, Fabienne Dobbels, Bernard Vrijens, Przemyslaw Kardas, Dyfrig Hughes, Michael Ramharter
- Wiener klinische Wochenschrift. 127(2015):379-384
Evaluation of intermittent preventive treatment of malaria against group B Streptococcus colonization in pregnant women: a nested analysis of a randomized controlled clinical trial of sulfadoxine/pyrimethamine versus mefloquine.
- Mesküre Capan-Melser, Ghyslain Mombo Ngoma, Daisy Akerey-Diop, Arti Basra, Heike Würbel, Mirjam Groger, Jean R. Mackanga, Rella Zoleko-Manego, Ulla Schipulle, Julia Schwing, Felix Lötsch, Khalid Rehman, Pierre-Blaise Matsiegui, Selidji T. Agnandji, Ayôla A. Adegnika, Sabine Bélard, Raquel González, Peter G. Kremsner, Clara Menendez, Michael Ramharter
- Journal of Antimicrobial Chemotherapy. 70(6):1898-1902
