The BNITM offers various molecular biological and serological detection methods for the diagnosis of tick-bite fever and spotted fever (Examination orders bacterial disease, only in German). These diseases, triggered by various rickettsiae, often appear clinically as fever, headache, rash and a necrotic skin area, the eschar.
If these symptoms occur after a tick bite in the tropics, subtropics or also here in Germany, it is called tick-bite fever, which can be transmitted by different tick species.
Different tick-bite fever rickettsiae can trigger this disease. In Central Europe, for example, Rickettsia aeschlimannii, Rickettsia helvetica, Rickettsia slovaca, Rickettsia raoultii, Rickettsia monacensis are common. If infected in the Mediterranean region, Mediterranean tick-bite fever may be present due to Rickettsia conorii; if infected in South Africa, for example, African tick-bite fever may be present due to Rickettsia africae.